The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-30
ncRNA Category:miRNA
Interaction Gene Symbol: Tcf3
Death Pathway:apoptosis
Expression Direction of ncRNA:down
Species:Mus musculus
Tissue:leukocyte cella
PMID: 22342458
Detail Description:

Beside the role in apoptosis, A1, like Bcl-2, Mcl-1 or Bcl-xL can interact with Beclin1, thereby inhibiting induction of autophagy, possibly via the disruption of Beclin1/hVps34 complexes .In this animal model, we have expressed an shRNA targeting all A1 isoforms, embedded in the microRNA-30 (miR30) backbone, under control of the hematopoiesis-specific Vav-gene promoter. 

Select the ncRNA symbol and transcript of gene
Mature of miR-30    Transcript of Tcf3    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.