ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-30

MI0000144	MIPF0000005	GCGACUGUAAACAUCCUCGACUGGAAGCUGUGAAGCCACAAAUGGGCUUUCAGUCGGAUGUUUGCAGCUGC	MIMAT0000128 mmu-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG	Landgraf et al. confirm that the 5' mature miRNA product is thepredominant one .
MI0000144	MIPF0000005	GCGACUGUAAACAUCCUCGACUGGAAGCUGUGAAGCCACAAAUGGGCUUUCAGUCGGAUGUUUGCAGCUGC	MIMAT0000129 mmu-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC	Landgraf et al. confirm that the 5' mature miRNA product is thepredominant one .
MI0000145	MIPF0000005	CUAAGCCAAGUUUCAGUUCAUGUAAACAUCCUACACUCAGCUGUCAUACAUGCGUUGGCUGGGAUGUGGAUGUUUACGUCAGCUGUCUUGGAGUAU	MIMAT0000130 mmu-miR-30b-5p	UGUAAACAUCCUACACUCAGCU
MI0000145	MIPF0000005	CUAAGCCAAGUUUCAGUUCAUGUAAACAUCCUACACUCAGCUGUCAUACAUGCGUUGGCUGGGAUGUGGAUGUUUACGUCAGCUGUCUUGGAGUAU	MIMAT0004524 mmu-miR-30b-3p	CUGGGAUGUGGAUGUUUACGUC
MI0000548	MIPF0000005	GAGUGACAGAUAUUGUAAACAUCCUACACUCUCAGCUGUGAAAAGUAAGAAAGCUGGGAGAAGGCUGUUUACUCUCUCUGCCUU	MIMAT0000514 mmu-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned and mapped to chromosome 4 in reference (MIR:MI0000547). A search of more recent mouse genome assemblies suggeststhe presence of a second locus encoding miR-30c on chromosome 1,represented by this entry.
MI0000547	MIPF0000005	ACCAUGUUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0004616 mmu-miR-30c-1-3p	CUGGGAGAGGGUUGUUUACUCC
MI0000548	MIPF0000005	GAGUGACAGAUAUUGUAAACAUCCUACACUCUCAGCUGUGAAAAGUAAGAAAGCUGGGAGAAGGCUGUUUACUCUCUCUGCCUU	MIMAT0005438 mmu-miR-30c-2-3p	CUGGGAGAAGGCUGUUUACUCU	miR-30c was cloned and mapped to chromosome 4 in reference (MIR:MI0000547). A search of more recent mouse genome assemblies suggeststhe presence of a second locus encoding miR-30c on chromosome 1,represented by this entry.
MI0000549	MIPF0000005	AAGUCUGUGUCUGUAAACAUCCCCGACUGGAAGCUGUAAGCCACAGCCAAGCUUUCAGUCAGAUGUUUGCUGCUACUGGCUC	MIMAT0000515 mmu-miR-30d-5p	UGUAAACAUCCCCGACUGGAAG
MI0000549	MIPF0000005	AAGUCUGUGUCUGUAAACAUCCCCGACUGGAAGCUGUAAGCCACAGCCAAGCUUUCAGUCAGAUGUUUGCUGCUACUGGCUC	MIMAT0017011 mmu-miR-30d-3p	CUUUCAGUCAGAUGUUUGCUGC
MI0000259	MIPF0000005	GGGCAGUCUUUGCUACUGUAAACAUCCUUGACUGGAAGCUGUAAGGUGUUGAGAGGAGCUUUCAGUCGGAUGUUUACAGCGGCAGGCUGCCA	MIMAT0000248 mmu-miR-30e-5p	UGUAAACAUCCUUGACUGGAAG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000259	MIPF0000005	GGGCAGUCUUUGCUACUGUAAACAUCCUUGACUGGAAGCUGUAAGGUGUUGAGAGGAGCUUUCAGUCGGAUGUUUACAGCGGCAGGCUGCCA	MIMAT0000249 mmu-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

Palm2,Sdccag3,Slain1,Pcdhb22,Zbtb34,Acap2,Tnik,Rps6ka5,Sema6d,Ehbp1,Mtmr6,Scn8a,Rsf1,Becn1,Ppargc1b
more » Palm2,Sdccag3,Slain1,Pcdhb22,Zbtb34,Acap2,Tnik,Rps6ka5,Sema6d,Ehbp1,Mtmr6,Scn8a,Rsf1,Becn1,Ppargc1b,Obfc2a,Arglu1,Gja6,Cacng7,Aff4,C1ql3,Ppp3r1,Setd5,Epb4.1,Snx27,Nfatc3,Azin1,Peli1,Btbd3,Zhx3,Jakmip2,Hmgcll1,Sema6a,Inhba,Araf,Abcb1b,Zfp174,Plxna2,Samd4,Fam49a,Pigk,Tnrc6a,Cars,Cdk19,Alg2,Scn2a1,Adam22,Slc7a1,Nlgn1,Ddit4,Mtdh,Sec61a2,Tcf7,Ipcef1,Kif21a,Qser1,Ythdc1,Nr3c1,Zkscan3,Slc7a5,Pcdhga11,Snip1,Lrrc55,P4ha2,Pggt1b,Setd1b,Dap,Ap1s2,Slc29a3,Celf2,Stxbp6,Ept1,Sox4,1190002N15Rik,Itpa,Lix1,Sh3rf1,Arid1a,Zbtb39,Pdzd8,Homer2,Acap3,Rtn4r,Ythdf3,Atp8b2,Grk4,Adar,Bach1,Ak1,Tnrc6c,Chd7,Slc6a15,Snx18,Gpcpd1,Zfp9,Mier3,Ppfibp1,Fam123b,Ppp2r4,Afap1,Kpna3,Cep350,8430427H17Rik,Bcl7c,Blcap,Pcdh17,D730040F13Rik,Mt1,Cox4i1,Ifngr1,Robo2,Prdm1,Kcnj6,Myh10,Spag9,Pitpnc1,Fam43a,Rabgap1l,Pfn2,Csda,Rev3l,Unc5c,Oprl1,Pitpna,Lhx1,Osmr,Spast,Pttg1ip,Insig2,Helz,Gabrb2,Yeats4,Usp45,Map3k5,Slc36a4,Med17,Csnk1g1,Samd8,Cd164,Khnyn,Tspan2,Tmc7,Gigyf2,Cdc37l1,Kif5c,AK010878,Arl6ip1,Nipa2,Klf2,Arid4b,D3Bwg0562e,Lsamp,Pmaip1,Shmt1,B4galt6,Slc39a10,Vps26b,Usp2,Ddx17,Enc1,Ccnjl,Gpm6b,Celf5,Baz2b,Tcp11l2,Nacc2,Ptgfrn,Grm5,Fam40a,Nsg1,Pde7a,Skp1a,Odz3,Fam109a,Znrf1,Antxr1,Mcf2l,Trip12,Zmym2,Slc30a4,Ski,Ptprz1,Igsf11,Epb4.1l1,Ywhag,Col9a3,Xpr1,Dio2,Fam155a,Nfat5,Twsg1,Cpeb4,Igf1r,Map3k1,Arid5b,Tcf3,Nek4,Lpgat1,Ankrd17,Qk,Pafah1b2,Vezt,Wdr82,Galnt7,Zdhhc21,Slc25a14,Nras,Srsf7,Gpt2,Eif4g2,Ccne2,Whsc1l1,Dnajc3,Plekha1,Mycn,Pank3,Atp6v1g2,4933439F18Rik,Jph4,Pnn,4930402H24Rik,Lhfpl2,Snai1,Vopp1,Rc3h2,Sfmbt1,Rmnd5a,Slc35e1,Csnk2a1,Tspan7,Wasl,Nhsl2,Herc2,Dag1,Acp2,AF064781,Grb10,Cotl1,Smap1,Klhdc2,Gnpat,Grk5,Gpr63,Omg,Nid1,Kcnc2,Mcl1,Gria2,Phactr3,Sgtb,Lrp8,Ankrd52,Coasy,Ptp4a2,Lancl1,Myh9,Zdhhc20,Fam117b,Papolg,Arpp19,Arfip1,Lrrc57,Bdp1,Gnai2,Adamts3,Peg3,Nr2c1,Avl9,Zfp36l1,B4galt5,Capn7,Dlg5,Camk2n1,Arl15,Pitpnm2,Frmpd1,Trim37,Akt3,Scn1a,Sv2b,Neto2,Riok3,Hsdl2,Ppm1l,Bdnf,Mecp2,Ide,Egfr,Camk2d,St8sia4,Vat1l,Egln2,Gpr125,Cry2,Aicda,Ncam1,Slc35a5,Zfp655,Slc6a6,Epha4,Runx1,Fndc3b,Kif5b,Rnf157,Pde4dip,Gnao1,Dlgap2,Mbnl1,Atp2a2,Hells,Adarb1,Pnkd,Hipk1,Tspyl1,Magi2,Gpm6a,Akap2,C330019G07Rik,Ppp3ca,Cyb5b,Abat,Slc7a11,Adam9,Fam49b,Trp53inp1,Nsd1,Neto1,Rgs8,Mtf1,C130071C03Rik,Trim44,Zfhx3,Fnip1,Pgm2l1,Rnf24,BC029127,Ucp2,Nfib,Lig3,Eno2,Gpr30,Glce,Cpox,Apc,Adnp,Daglb,Ptprd,Fnip2,Necab1,Scara5,Lemd3,Pgam5,Sobp,Fem1b,Rps6ka3

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

mmu04360	Axon guidance	Epha4,Unc5c,Gnai2,Sema6a,Robo2,Nfatc3,Nras,Plxna2,Ppp3ca,Nfat5,Ppp3r1,Sema6d,	2.11E-5
mmu04720	Long-term potentiation	Gria2,Grm5,Araf,Camk2d,Nras,Rps6ka3,Ppp3ca,Ppp3r1,	2.46E-4
mmu04530	Tight junction	Csnk2a1,Myh10,Magi2,Gnai2,Myh9,Nras,Akt3,Csda,Epb4.1l1,Epb4.1,	7.00E-4
mmu04730	Long-term depression	Gria2,Grm5,Gnai2,Araf,Igf1r,Nras,Gnao1,	1.82E-2
mmu04722	Neurotrophin signaling pathway	Rps6ka5,Bdnf,Map3k5,Camk2d,Nras,Ywhag,Rps6ka3,Map3k1,Akt3,	2.32E-2

mmu05213	Endometrial cancer	Egfr,Tcf7,Araf,Nras,Apc,Akt3,	2.34E-2
mmu04114	Oocyte meiosis	Ccne2,Igf1r,Camk2d,Skp1a,Ywhag,Rps6ka3,Ppp3ca,Ppp3r1,	4.63E-2
mmu04310	Wnt signaling pathway	Csnk2a1,Tcf7,Nfatc3,Camk2d,Skp1a,Apc,Ppp3ca,Nfat5,Ppp3r1,	5.37E-2
mmu05215	Prostate cancer	Egfr,Ccne2,Tcf7,Araf,Igf1r,Nras,Akt3,	5.58E-2
mmu05214	Glioma	Egfr,Araf,Igf1r,Camk2d,Nras,Akt3,	5.80E-2
mmu04520	Adherens junction	Egfr,Csnk2a1,Snai1,Wasl,Tcf7,Igf1r,	1.18E-1
mmu04370	VEGF signaling pathway	Nfatc3,Nras,Ppp3ca,Akt3,Nfat5,Ppp3r1,	1.18E-1
mmu04662	B cell receptor signaling pathway	Nfatc3,Nras,Ppp3ca,Akt3,Nfat5,Ppp3r1,	1.45E-1
mmu05221	Acute myeloid leukemia	Tcf7,Araf,Nras,Runx1,Akt3,	1.92E-1
mmu05210	Colorectal cancer	Egfr,Tcf7,Araf,Igf1r,Apc,Akt3,	1.94E-1
mmu04010	MAPK signaling pathway	Egfr,Cacng7,Rps6ka5,Bdnf,Map3k5,Nras,Rps6ka3,Ppp3ca,Map3k1,Akt3,Ppp3r1,	2.11E-1
mmu04650	Natural killer cell mediated cytotoxicity	Ifngr1,Araf,Nfatc3,Nras,Ppp3ca,Nfat5,Ppp3r1,	2.28E-1
mmu05218	Melanoma	Egfr,Araf,Igf1r,Nras,Akt3,	3.92E-1
mmu05219	Bladder cancer	Egfr,Rps6ka5,Araf,Nras,	3.98E-1
mmu04660	T cell receptor signaling pathway	Nfatc3,Nras,Ppp3ca,Akt3,Nfat5,Ppp3r1,	6.23E-1
mmu04914	Progesterone-mediated oocyte maturation	Gnai2,Araf,Igf1r,Rps6ka3,Akt3,	6.76E-1
mmu04012	ErbB signaling pathway	Egfr,Araf,Camk2d,Nras,Akt3,	7.24E-1
mmu04144	Endocytosis	Egfr,Acap3,Grk5,Grk4,Igf1r,Acap2,Wwp1,Smap1,	7.29E-1
mmu05223	Non-small cell lung cancer	Egfr,Araf,Nras,Akt3,	7.38E-1
mmu05014	Amyotrophic lateral sclerosis (ALS)	Gria2,Map3k5,Ppp3ca,Ppp3r1,	8.38E-1
mmu04810	Regulation of actin cytoskeleton	Egfr,Myh10,Wasl,Pfn2,Araf,Myh9,Nras,Apc,	9.78E-1
mmu04120	Ubiquitin mediated proteolysis	Herc2,Trim37,Skp1a,Trip12,Map3k1,Wwp1,	9.99E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0050804	regulation of synaptic transmission	Gria2,Mecp2,Bdnf,Grm5,Gnai2,Nlgn1,Nras,Ywhag,Ppp3ca,	5.50E-4
GO:0051969	regulation of transmission of nerve impulse	Gria2,Mecp2,Bdnf,Grm5,Gnai2,Nlgn1,Nras,Ywhag,Ppp3ca,	8.62E-4
GO:0031644	regulation of neurological system process	Gria2,Mecp2,Bdnf,Grm5,Gnai2,Nlgn1,Nras,Ywhag,Ppp3ca,	1.23E-2
GO:0000904	cell morphogenesis involved in differentiation	Ptprz1,Antxr1,Epha4,Bdnf,Myh10,Sema6a,Kif5c,Robo2,Myh9,Apc,Ppp3r1,Rtn4r,	2.09E-2
GO:0044057	regulation of system process	Gria2,Mecp2,Bdnf,Grm5,Gnai2,Nlgn1,Nras,Ywhag,Ppp3ca,Atp2a2,Gnao1,	4.44E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value