The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00003055
RNA/Protein Symbol 1:MIR23A(miR-23a)
RNA/Protein Category 1: miRNA
RNA/Protein Symbol 2: MYH1 mRNA(Myh 1)
RNA/Protein Category 2: mRNA
Validated Method: Luciferase reporter assay
Tissue:  
PMID: 22771720 
Detail description:

Using bioinformatics analyses, miR-23a is predicted to target multiple adult fast myosin heavy chain (Myh) genes, including Myh 1, 2 and 4. Luciferase reporter assays show that miR-23a directly targets the 3' untranslated regions (UTRs) of these mRNAs. 

The Predicated Binding Sites between MIR23A and MYH1
By miRanda Structure Match Score Energy Score MIR23A Location MYH1 Location
The Predicated Binding Sites between MIR23A and MYH1
By RIsearch Structure MIR23A Location MYH1 Location Score 
Query:    3' GGGUU---CCUGGGGA---UGGGAUUU 5'
          ::||      |||:|     ::|||||
Target:   5' UUCAUGUUUUACCUCACUGUUUCUAAA 3'
2-22 47-73 -9.13
The Predicated Binding Sites of MYH1
RBPBD 

					

					

						RsiteDB
						
					

						BindN
						
							 

								
					

					

						BindN+
						
							 

								
					

					

					    RNAbindR
						
                              
	 
								
					

					

					    Pprint
						
                            

								
					



				 
	
            			
	

	
    
	
	  
	 

      

	  
Visualization:
	  
	  

	  Select the center nodes:
	   First Node
	   Second Node
	  Both the Nodes	
 
      
Select the Level of Neighbour:
	   First Neighbour
	   Second Neighbour  
	  

	        
	  

	 
	 
	


 
	 

	  The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
	  the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes. 
	  
The 'First Neighbour' represents the sub-network of direct interacting with the center node, 
	  the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. 
	  Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
	 


	  

	   
	
	

  





	

		

           			
				
	
                   The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
 
				   The Binding page: representing the predicted binding sites and/or constants.
 
				   The Network page: representing the interaction sub-network of interacting RNA/Protein.