The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00003043
RNA/Protein Symbol 1:MIR218-2(miR-218)
RNA/Protein Category 1: miRNA
RNA/Protein Symbol 2: MMP9 mRNA(MMP-9)
RNA/Protein Category 2: mRNA
Validated Method:
Tissue:  
PMID: 22766851 
Detail description:

Importantly, western blot assays demonstrated that miR-218 can reduce protein levels of LEF1 and MMP-9. 

The Predicated Binding Sites between MIR218-2 and MMP9
By miRanda Structure Match Score Energy Score MIR218-2 Location MMP9 Location
The Predicated Binding Sites between MIR218-2 and MMP9
By RIsearch Structure MIR218-2 Location MMP9 Location Score
Query:    3' GCUUGAUCUAA--CCAU 5'
          ||::: :|:|   |||:
Target:   5' CGGGUCGGGUGGAGGUG 3'
5-19 113-129 -6.95
The Predicated Binding Sites of MMP9
RBPBD
RsiteDB
BindN
BindN+
RNAbindR
Pprint
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.