The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000228
RNA/Protein Symbol 1:DHPS
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: WDR83 mRNA
RNA/Protein Category 2: other
Validated Method:
Tissue:  
PMID: 22491477 
Detail description:

Here, we found that the protein-coding gene, deoxyhypusine synthase (DHPS), as the NAT of WDR83, concordantly regulated the expression of WDR83 mRNA and protein. Conversely, WDR83 also regulated DHPS by antisense pairing in a concordant manner. WDR83 and DHPS were capable of forming an RNA duplex at overlapping 3` untranslated regions and this duplex increased their mutual stability, which was required for the bidirectional regulation. 

The Predicated Binding Sites between DHPS and WDR83
By miRanda Structure Match Score Energy Score DHPS Location WDR83 Location
The Predicated Binding Sites between DHPS and WDR83
By RIsearch Structure DHPS Location WDR83 Location Score
Query:    3' CGUCUCUAGAAUAAGAUGGUAUCUGAAG---UCCUU 5'
          ||:|| |||||    |:|     ||       ||||
Target:   5' GCGGA-AUCUUUGGGUGCG---AACCCACAUUGGAA 3'
1317-1349 4-35 -10.90
The Predicated Binding Sites of WDR83
RBPBD
RsiteDB
BindN
BindN+
RNAbindR
Pprint
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.