The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000095
RNA/Protein Symbol 1:IGF2-AS
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: IGF2 mRNA
RNA/Protein Category 2: mRNA
Validated Method:
Tissue:  
PMID: 12702581 
Detail description:

We have examined the expression of IGF2 and IGF2-AS in normal tissue, breast and ovarian tumors, and 25 informative, well-characterized Wilms` tumors and determined the relationship between IGF2 and IGF2-AS imprinting. 

The Predicated Binding Sites between IGF2-AS and IGF2
By miRanda Structure Match Score Energy Score IGF2-AS Location IGF2 Location
The Predicated Binding Sites between IGF2-AS and IGF2
By RIsearch Structure IGF2-AS Location IGF2 Location Score
The Predicated Binding Sites of IGF2
RBPBD
RsiteDB
BindN
>sp|P01344|IGF2_HUMAN Insulin-like growth factor II OS=Homo sapiens GN=IGF2 PE=1 SV=1

Sequence:    MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Prediction:  ------+-------------------+-+------------------+--+-++--++++
Confidence:  888455727789969998938655527362256777887595777976455557228978

Sequence:    RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Prediction:  ++++--------+------------++++++++-++--+-------+----+-------+
Confidence:  985846877879457776897435667686585464324675525473474565424226

Sequence:    QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Prediction:  +++++-++------+-++-+---------+-+++-+-----------+--------++++
Confidence:  778783885623368587474573785755247728365574324345334332236576


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|P01344|IGF2_HUMAN Insulin-like growth factor II OS=Homo sapiens GN=IGF2 PE=1 SV=1

Sequence:    MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Prediction:  -----++-------------------------+--+--+-------------++---+++
Confidence:  327243425789999998999788765773323113755695897842312334332535

Sequence:    RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Prediction:  ++++---------------------++-++-+--+--------+--+----+-------+
Confidence:  864634755244242255597224543374272331223674344252134423123217

Sequence:    QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Prediction:  +++++-++--+---+-++-++--+--------++-+-----------+-------+++++
Confidence:  476691881333367396274463385861634325454485412235122434155356


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>P01344|IGF2
Sequence:    MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Prediction:  -+++++++--------------------------++----------------++++++++
Confidence:  355857752011000000000000001003432156000000000013422167677769

Sequence:    RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Prediction:  +++++----------------------------------------------+++++++++
Confidence:  989772234411412102101223120121121021330100011211321766887879

Sequence:    QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Prediction:  ++++++++++++++++++++++-++----------+--------------------+-++
Confidence:  998999999899999899888926614020023248423412243123020111015256

Sequence:    
Prediction:  -
Confidence:  0

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Prediction:  -++++----------------------------------------+-++---++++++++
Confidence:  234440222000000000000000000000000000000000000403412059899999

Sequence:    RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Prediction:  ++++++--++++-----+----+--+--+--+-------------------+--+--+++
Confidence:  996977225444310103001043143141353230023201000003110512522367

Sequence:    QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Prediction:  +++++++++++++-++++++++++---------+-+-+-----------+---+-+---+
Confidence:  888577895654524598597434211013203425230000030112243323242333

Sequence:    
Prediction:  
Confidence:  

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.