The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000067
RNA/Protein Symbol 1:antisense c-myc RNA
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: MYC mRNA(c-myc)
RNA/Protein Category 2: mRNA
Validated Method:
Tissue: HeLa cells//Burkitt lymphoma BL-60 cells//Diploid fibroblasts 
PMID: 7990819 
Detail description:

These data imply that the c-myc antisense transcripts might take part in the regulation of human c-myc gene expression. 

The Predicated Binding Sites between antisense c-myc RNA and MYC
By miRanda Structure Match Score Energy Score antisense c-myc RNA Location MYC Location
The Predicated Binding Sites between antisense c-myc RNA and MYC
By RIsearch Structure antisense c-myc RNA Location MYC Location Score
The Predicated Binding Sites of MYC
RBPBD
RsiteDB
BindN
>sp|P01106|MYC_HUMAN Myc proto-oncogene protein OS=Homo sapiens GN=MYC PE=1 SV=1

Sequence:    MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPP
Prediction:  -----+-+++-+------------------------+----------------------+
Confidence:  869375365634354363735484889965723222422622263224643697674244

Sequence:    LSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPD
Prediction:  -++++++++-+--+--------+--+-+++-+-+--------------------------
Confidence:  287688864253257862252585242455252526748789589987778468897588

Sequence:    DETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQD
Prediction:  ------------------+---+----+--+++-++++++++++++-++--++++-----
Confidence:  876793599989996676455465625446568249778698865946722566563747

Sequence:    LSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVL
Prediction:  ---------------------+++++++-+--++-++++--+--++++++++++------
Confidence:  926662478776997635722678698426236634665236366575787657454899

Sequence:    HEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRC
Prediction:  ---+-++++++++---------------+++++++++++++++++++++++++-----+-
Confidence:  785526577765524378898979625258859799999786878688965652667264

Sequence:    HVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHN
Prediction:  +-+++--++--++++++++++-++-+----+--+--++++++++++++-++++-+++--+
Confidence:  546642345326789975974378382325585623456897986967256663777227

Sequence:    VLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLL
Prediction:  +--++++++-++----------------+--+-----+-+-+------------------
Confidence:  522659887277435582969648434464366778255555782726454378587544

Sequence:    RKRREQLKHKLEQLRNSCA
Prediction:  ++++++-+------+----
Confidence:  7588782732652864357


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|P01106|MYC_HUMAN Myc proto-oncogene protein OS=Homo sapiens GN=MYC PE=1 SV=1

Sequence:    MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPP
Prediction:  -----+--++-----------------------------------++--++--------+
Confidence:  327253333622555566827685989888856673454632452541154264454234

Sequence:    LSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPD
Prediction:  ++++++------------------------------------------------------
Confidence:  487884115466857777464514526646767689899999899978787487699887

Sequence:    DETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQD
Prediction:  --------------+---+---+----+--+++--+-++++++++++++--+++------
Confidence:  784581236623554233415545535533337226134344644634422434123888

Sequence:    LSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVL
Prediction:  ---------------------+-+++----------------------------------
Confidence:  747875856365756752512415451211232265575978898788688778999999

Sequence:    HEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRC
Prediction:  ----------------------------++--+++++++++-++-++++-+-------+-
Confidence:  999999999999999999999989825245165377548532443335613132325143

Sequence:    HVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHN
Prediction:  +-+-+++++------+---++-++-+--------+-++++++++++++-+----+++-++
Confidence:  425355434343531325333364245535283242344784676834231224486277

Sequence:    VLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLL
Prediction:  ++-++++++-+-----------------+--+----++----------------------
Confidence:  341858875443667692889357333372153157445382743625572256575655

Sequence:    RKRREQLKHKLEQLRNSCA
Prediction:  ++-------------+-+-
Confidence:  6332725345872713434


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>P01106|MYC
Sequence:    MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPP
Prediction:  -----+----------------------------------------------------++
Confidence:  131215203411100010000100000000000000000011421330031001011455

Sequence:    LSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPD
Prediction:  +++++-------------------------------------------------------
Confidence:  677752110100100000000000000000000000000000000000000000000000

Sequence:    DETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQD
Prediction:  ----------+++++++++++-+----+--+++-+++--+----------+---------
Confidence:  000101101066556988867352144524558478613532241232117324314100

Sequence:    LSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVL
Prediction:  ----------+-----++------------------------------------------
Confidence:  020000210254234265042301100000000100000000000000000000000000

Sequence:    HEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRC
Prediction:  --------------------------------------------------+------++-
Confidence:  000000000000000000000000010122111132202001110132435232112552

Sequence:    HVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHN
Prediction:  ----+--++++++------+--++-+-+--+--+++-++++++++++++-+-+-++++++
Confidence:  202363488656522220352167152533820695498999899976745374887788

Sequence:    VLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLL
Prediction:  --+++++++-++-+-+-+-------++-+--+----++--+----------+--------
Confidence:  436889986376453616211220165383363344881352112110134500112242

Sequence:    RKRREQLKHKLEQLRNSCA
Prediction:  --+++++-++-++-+++++-
Confidence:  44875754762584778870

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPP
Prediction:  --+---+--+-+------------------------------------------------
Confidence:  233223411523200010000000000000000000000000001221000000001031

Sequence:    LSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPD
Prediction:  ++--+-++----------------------------------------------------
Confidence:  361143533312211001100121011101202100000000000000000000000000

Sequence:    DETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQD
Prediction:  ------++------++++--+------+++-+++----++--++---------+------
Confidence:  000002340000126575323021012443144423123422441322323223211010

Sequence:    LSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVL
Prediction:  -----------------+--++--------------------------------------
Confidence:  101000000000000125234531010200000000000000000000000000000000

Sequence:    HEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRC
Prediction:  ---------------------------+++++++++++++-++---+------+---++-
Confidence:  000000000000000000000000001699878869555533530233212304303533

Sequence:    HVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHN
Prediction:  --+-+-+-+++++-+-------++-+++-+++++++++++++++++++++++++++++++
Confidence:  135332637447524200020369253523645734498899999989945566579889

Sequence:    VLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLL
Prediction:  +++++++---++----------------+--+-+---+-------------+--------
Confidence:  858995512254001002000000010363243511230111110200322410101022

Sequence:    RKRREQLKHKLEQLRNSCA
Prediction:  -++++++-++----+++++
Confidence:  2475343166223367773

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.