The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000064
RNA/Protein Symbol 1:antisense N-myc RNA
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: MYCN mRNA(N-myc)
RNA/Protein Category 2: mRNA
Validated Method: Double RNase protection assay procedure
Tissue: SCLC cell lines//Neuroblastoma cell line 
PMID: 1695323 
Detail description:

N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts. 

The Predicated Binding Sites between antisense N-myc RNA and MYCN
By miRanda Structure Match Score Energy Score antisense N-myc RNA Location MYCN Location
The Predicated Binding Sites between antisense N-myc RNA and MYCN
By RIsearch Structure antisense N-myc RNA Location MYCN Location Score
The Predicated Binding Sites of MYCN
RBPBD
RsiteDB
BindN
>sp|P04198|MYCN_HUMAN N-myc proto-oncogene protein OS=Homo sapiens GN=MYCN PE=1 SV=2

Sequence:    MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPP
Prediction:  --+-++++------+--------------------------++----------------+
Confidence:  645367655424774556647849457738899895854435624425844697674244

Sequence:    LSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGF
Prediction:  -+-++-----++--+------------------------------+--------------
Confidence:  362584232345245249469999989372385678777645334543499989996544

Sequence:    SAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELA
Prediction:  --+-+--+----+-++-+-+++++++-+++-++--+++++-++-+-+--+----------
Confidence:  258247374423545439258855982875255328856927524252294235757688

Sequence:    HPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPG
Prediction:  ------------------++----------+---------+---------------++++
Confidence:  379878988999976452562332734525642444254464545542534232324988

Sequence:    GRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTIT
Prediction:  ++++++--++--+++---+-+-------------------+-++++++++++--++-+-+
Confidence:  898685225733677322554344555677798998979745568999889923555556

Sequence:    VRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLK
Prediction:  -+-+----++++-++----------------+--++++------+++++-+++-+++--+
Confidence:  674625324559277225693488452343354455565224325457839782667257

Sequence:    SVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKV
Prediction:  +---++-++++++++++++++++++++---+++++++++-------------+--+--+-
Confidence:  546347389686976677888988457232558887485226282869648746474566

Sequence:    VILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC
Prediction:  ----+--------------------+-+-+--+--------+--
Confidence:  77825624273272757769896445273732556227426724


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|P04198|MYCN_HUMAN N-myc proto-oncogene protein OS=Homo sapiens GN=MYCN PE=1 SV=2

Sequence:    MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPP
Prediction:  ----+-+--++---+-------------------------------++-++--------+
Confidence:  642443425333434236467768278838897773888752123144256153443244

Sequence:    LSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGF
Prediction:  -++++---------------------------------------------------+---
Confidence:  275573234445769538789999999889998798879999795584258823455233

Sequence:    SAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELA
Prediction:  +-+----+----+----+------------------+-+--+------------------
Confidence:  435429343535443134343263336223412311435165123324223246699895

Sequence:    HPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPG
Prediction:  -------------------+----------------------------------------
Confidence:  788678725675776372451342343323353777678766569987998999999777

Sequence:    GRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTIT
Prediction:  ----------------------------------------+--+++++++++--+-----
Confidence:  857869999999999999999999999999999999969744157647555661425142

Sequence:    VRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLK
Prediction:  -+-+-----+++++++++---+--++-+++++-------------++++-++-------+
Confidence:  462335152589685553262654441465562415124223421536726333231134

Sequence:    SVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKV
Prediction:  +++++++++++++++-+----+++-+++++++++++-+-----------------+--+-
Confidence:  443656596485944241121596287343867875444557491899477623372253

Sequence:    VILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC
Prediction:  ---++----------------------+-------------+--
Confidence:  25743637272362657336656563552336155258516415


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>P04198|MYCN
Sequence:    MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPP
Prediction:  ---+----------------------------------------+-+------------+
Confidence:  123511211122123101000000100000000000000121345262132001010335

Sequence:    LSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGF
Prediction:  --++--------------------------------------------------------
Confidence:  345543210000000000000000000000000000000000001000000021102321

Sequence:    SAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELA
Prediction:  ------------+----+-+----------------------------+--+-------+
Confidence:  201010110233512235153200101112112324422421121122732742344236

Sequence:    HPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPG
Prediction:  -------+++++++++-+------------------------------------------
Confidence:  301211157557767716330100000000000000000000000000000000000000

Sequence:    GRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTIT
Prediction:  -------------------------------------------+++--------------
Confidence:  000000000000000000000000000000000000010143457543332311132211

Sequence:    VRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLK
Prediction:  --------------------+------+++++++++--------+-----------+--+
Confidence:  020000000102242121216423023657988785340012016122303110428216

Sequence:    SVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKV
Prediction:  +--+++++++++++++++++++++++++++++++++-++++-+-+-------++-+--+-
Confidence:  742769899799988877587998999757999996488664737311330165284464

Sequence:    VILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC
Prediction:  -++++--+---------++------++++++++++++--+-+++-
Confidence:  465782373132120136600123465569878658844848760

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPP
Prediction:  -++---++--------------------------------+---+---------------
Confidence:  233213430023001121000000000000000000000030233131000000000011

Sequence:    LSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGF
Prediction:  -+--+--------------------------------------------+------++++
Confidence:  352031200000000000000000000000000000000000011000130000125446

Sequence:    SAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELA
Prediction:  +---------+++------------------------------+-++-------------
Confidence:  322023031355522123221201110000000112120322242453212110001110

Sequence:    HPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPG
Prediction:  ---------------+--+++----+----------------------------------
Confidence:  000010000000132523783212231211000000000000000000000000000000

Sequence:    GRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTIT
Prediction:  ------------------------------------------++++++++++++------
Confidence:  010000010000000000000000000000000000000012578656556443221210

Sequence:    VRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLK
Prediction:  ---------+++--+-++--++++++-+-+-+++++-+------+--++-+++-----++
Confidence:  020202011344334253124543453425244653340020023134715441223235

Sequence:    SVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKV
Prediction:  -+++++++++++++++++++++++++++++++++---++----------------+--+-
Confidence:  354889698789969645567689989757984502243011002000000010253242

Sequence:    VILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC
Prediction:  +-----------+--+--+--------+++++++-++------+
Confidence:  42123011212141042252010102334864432441001224

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.