Detail-Interactions: | |
RAID ID: | RRI00000046 |
---|---|
RNA/Protein Symbol 1: | PTENP1 |
RNA/Protein Category 1: | lncRNA |
RNA/Protein Symbol 2: | MIR20A(miR-20a) |
RNA/Protein Category 2: | miRNA |
Validated Method: | Dual Luciferase reporter assay, RT-PCR, Western blot |
Tissue: | |
PMID: | 20577206 |
Detail description: | In DU145 prostate cancer cells, PTEN-targeting microRNAs miR-19b and miR-20a suppress both PTEN and PTENP1 mRNA abundance (Fig. 1d, Supplementary Fig. 3a). |
The Predicated Binding Sites between MIR20A and PTENP1 | |||||
By miRanda | Structure | Match Score | Energy Score | MIR20A Location | PTENP1 Location |
Query: 3' gaUGGACGUGA-UAUU-----CGUGAAAu 5' |:: | |:| |||| ||||||| Ref: 5' caAUUAGGAUUAAUAAAGAUGGCACUUUc 3' |
143.00 | -8.77 | 2-22 | 2230-2258 | |
Query: 3' gaUGGACGUGAUAUUCGUGAAAu 5' :|:||: | | |||:||| Ref: 5' cuGCUUGUUGUUUUCGCAUUUUu 3' |
137.00 | -14.73 | 2-22 | 2617-2639 | |
Query: 3' gauggacGUGAUAUUCGUGAAau 5' | || | |||||| Ref: 5' aucauacCCCUUU--GCACUUgu 3' |
121.00 | -10.38 | 3-17 | 2380-2400 |
The Predicated Binding Sites between MIR20A and PTENP1 | ||||
By RIsearch | Structure | MIR20A Location | PTENP1 Location | Score |
Query: 3' AAAGU-GCUUAUAGUGCAGGUAG 5' |||| ||| ||||||:|| Target: 5' UUUCUUCGA-----ACGUCCGUC 3' |
2-23 | 3011-3028 | -16.95 |
The Predicated Binding Sites of PTENP1 | |
RBPBD | |
RsiteDB | |
BindN | |
BindN+ | |
RNAbindR | |
Pprint |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.