The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000044
RNA/Protein Symbol 1:PTENP1
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: MIR19B1(miR-19b)
RNA/Protein Category 2: miRNA
Validated Method: Dual Luciferase reporter assay, RT-PCR, Western blot
Tissue:  
PMID: 20577206 
Detail description:

In DU145 prostate cancer cells, PTEN-targeting microRNAs miR-19b and miR-20a suppress both PTEN and PTENP1 mRNA abundance (Fig. 1d, Supplementary Fig. 3a). 

The Predicated Binding Sites between MIR19B1 and PTENP1
By miRanda Structure Match Score Energy Score MIR19B1 Location PTENP1 Location 
   Query:    3' cgaCCUACGUUUGG-ACGUUUUga 5'
                   | |  :||||: |||||||  
   Ref:      5' acaGAAAUUAAACUAUGCAAAAau 3'
139.00 -11.19 3-21 3187-3210 
   Query:    3' cgaccuACGUUUGGACGUUUUGa 5'
                      | | | ||||||:|:| 
   Ref:      5' agccauUUCCAUCCUGCAGAGCc 3'
129.00 -16.33 2-18 686-708 
   Query:    3' cgACCUACGUUUG--GACGUUUUGa 5'
                  || | |||| :  |||:|||:| 
   Ref:      5' guUGCA-GCAAUUCACUGUAAAGCu 3'
126.00 -18.23 2-22 1124-1147
The Predicated Binding Sites between MIR19B1 and PTENP1
By RIsearch Structure MIR19B1 Location PTENP1 Location Score 
Query:    3' AGUUUUGCAGGUU--------UGCAUC--CAGC 5'
          ||: |||||||:          ||||   ||||
Target:   5' UCG-AACGUCCGUCGUGUACUUCGUAAGUGUCG 3'
1-23 2992-3023 -19.32
The Predicated Binding Sites of PTENP1
RBPBD 

					

					

						RsiteDB
						
					

						BindN
						
							 

								
					

					

						BindN+
						
							 

								
					

					

					    RNAbindR
						
                              
	 
								
					

					

					    Pprint
						
                            

								
					



				 
	
            			
	

	
    
	
	  
	 

      

	  
Visualization:
	  
	  

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	  The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
	  the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes. 
	  
The 'First Neighbour' represents the sub-network of direct interacting with the center node, 
	  the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. 
	  Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
	 


	  

	   
	
	

  





	

		

           			
				
	
                   The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
 
				   The Binding page: representing the predicted binding sites and/or constants.
 
				   The Network page: representing the interaction sub-network of interacting RNA/Protein.