The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000023
RNA/Protein Symbol 1:GJA1P1(CONNEXIN 43 pseudogene)
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: MIR206(miR-206)
RNA/Protein Category 2: miRNA
Validated Method: Dual Luciferase reporter assay, RT-PCR
Tissue:  
PMID: 20577206 
Detail description:

Alignments of gene and pseudogenes sequences show that microRNA-binding sites are well conserved; for example, the miR-145 binding site on OCT4 and its pseudogenes OCT4-pg1, 3, 4 and 5 (Supplementary Fig. 11a); miR-1 family binding sites on CONNEXIN 43 (CX43) and its pseudogene (Supplementary Fig. 11b). 

The Predicated Binding Sites between MIR206 and GJA1P1
By miRanda Structure Match Score Energy Score MIR206 Location GJA1P1 Location 
   Query:    3' ggUGUGUGAAGGAA-UGUAAGGu 5'
                  ||  |:|| :|| ||||||| 
   Ref:      5' uuACUAAUUUGUUUGACAUUCCa 3'
159.00 -17.46 2-21 3058-3080 
   Query:    3' ggugugugaaggaaUGUAAGGu 5'
                              ||||||| 
   Ref:      5' aagucccugcuaaaACAUUCCa 3'
140.00 -13.36 2-9 1920-1941 
   Query:    3' gguGU-GUGAAGGAAU-GUAAGGu 5'
                   || |||||::| | |||||| 
   Ref:      5' uacCAUCACUUUUUCAUCAUUCCu 3'
134.00 -22.95 2-20 2136-2159
The Predicated Binding Sites between MIR206 and GJA1P1
By RIsearch Structure MIR206 Location GJA1P1 Location Score 
Query:    3' GGAAUG--UAAGGAAGUGUGUGG 5'
          ||||     ||||  |||:||||
Target:   5' CCUUUAGUUUUCCGACACGCACC 3'
2-22 1297-1319 -20.44
The Predicated Binding Sites of GJA1P1
RBPBD 

					

					

						RsiteDB
						
					

						BindN
						
							 

								
					

					

						BindN+
						
							 

								
					

					

					    RNAbindR
						
                              
	 
								
					

					

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Visualization:
	  
	  

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	  The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
	  the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes. 
	  
The 'First Neighbour' represents the sub-network of direct interacting with the center node, 
	  the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. 
	  Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
	 


	  

	   
	
	

  





	

		

           			
				
	
                   The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
 
				   The Binding page: representing the predicted binding sites and/or constants.
 
				   The Network page: representing the interaction sub-network of interacting RNA/Protein.