The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RRI00000013
RNA/Protein Symbol 1:CDK4PS
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: MIR34A(miR-34a)
RNA/Protein Category 2: miRNA
Validated Method: Dual Luciferase reporter assay, RT-PCR
Tissue:  
PMID: 20577206 
Detail description:

Further examples of such conservation include: miR-34 family binding site on CDK4PS (Supplementary Fig. 12); miR-182 binding site on FOXO3B (Supplementary Fig. 13); miR-17 family binding site on E2F3P1 (Supplementary Fig. 14); miR-143 and let-7 family binding sites on KRAS1P (Supplementary Fig. 15). 

The Predicated Binding Sites between MIR34A and CDK4PS
By miRanda Structure Match Score Energy Score MIR34A Location CDK4PS Location 
   Query:    3' uguuGGUCGAUUCU-GUGACGGu 5'
                    ||| : :| | |||| || 
   Ref:      5' guucCCAUUAGAAAUCACUCCCa 3'
117.00 -13.32 2-19 272-294 
   Query:    3' uguuggUCGAUUCUGUGACGGu 5'
                      |||  |  :|||||: 
   Ref:      5' agagggAGCACAACUACUGCUg 3'
116.00 -10.75 2-17 833-854 
   Query:    3' ugUUGGUCG-AUUCU----GUGACGGu 5'
                  |||:  |  ||||    |||| || 
   Ref:      5' gaAACUCUCAAAAGAGUUCCACUCCCa 3'
110.00 -14.51 2-21 217-243
The Predicated Binding Sites between MIR34A and CDK4PS
By RIsearch Structure MIR34A Location CDK4PS Location Score 
Query:    3' UGGCAGUGUCUUAGCUGGUUGU 5'
          ||||||: |||   |:  :|||
Target:   5' ACCGUCGAAGAUAAGGAAGACA 3'
1-22 953-974 -18.15
The Predicated Binding Sites of CDK4PS
RBPBD 

					

					

						RsiteDB
						
					

						BindN
						
							 

								
					

					

						BindN+
						
							 

								
					

					

					    RNAbindR
						
                              
	 
								
					

					

					    Pprint
						
                            

								
					



				 
	
            			
	

	
    
	
	  
	 

      

	  
Visualization:
	  
	  

	  Select the center nodes:
	   First Node
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Select the Level of Neighbour:
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	  The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
	  the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes. 
	  
The 'First Neighbour' represents the sub-network of direct interacting with the center node, 
	  the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. 
	  Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
	 


	  

	   
	
	

  





	

		

           			
				
	
                   The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
 
				   The Binding page: representing the predicted binding sites and/or constants.
 
				   The Network page: representing the interaction sub-network of interacting RNA/Protein.