| Detail-Interactions: | |
| RAID ID: | RPI00001616 |
|---|---|
| RNA/Protein Symbol 1: | TERC(htr) |
| RNA/Protein Category 1: | snoRNA |
| RNA/Protein Symbol 2: | TERT(hTRT) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | |
| Tissue: | lung cancer tissue |
| PMID: | 11783109 |
| Detail description: | Telomerase activity, hTR expression and hTRT/hEST2 are frequently detected at higher levels in NSCLC than the pericancerous normal tissues. |
| The Predicated Binding Sites between TERC and TERT | |||||
| By miRanda | Structure | Match Score | Energy Score | TERC Location | TERT Location |
| The Predicated Binding Sites between TERC and TERT | ||||
| By RIsearch | Structure | TERC Location | TERT Location | Score |
| The Predicated Binding Sites of TERT | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|O14746|TERT_HUMAN Telomerase reverse transcriptase OS=Homo sapiens GN=TERT PE=1 SV=1 Sequence: MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPW Prediction: --+--+-+--++--+++-+---------++--++--+---+--+---+------------ Confidence: 538328283695348543649659724967555563766257354565888959998974 Sequence: DARPPPAAPSFRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVR Prediction: --+--+-+-+-+----------+---+---+--+-------------+--+-+--+++-+ Confidence: 667435252547373793599959836653645628689989885649225244365657 Sequence: SYLPNTVTDALRGSGAWGLLLRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGA Prediction: ++--+--+---+-+-------++-----------+------------+------------ Confidence: 766253852468353734669448878989799959988999952474386655823755 Sequence: ATQARPPPHASGPRRRLGCERAWNHSVREAGVPLGLPAPGARRRGGSASRSLPLPKRPRR Prediction: -++-+++++++++++++--++-++---+----------+++++++++++++-++++++++ Confidence: 367395556696788942257464328737574756337759998896896265899799 Sequence: GAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAEEATSLEGALSGTRHSHPSVG Prediction: +-+++--++---+-++-+++++++++-+--------+--------+---+++++++++-- Confidence: 525762274242644638669898862755676236733226227423465785765724 Sequence: RQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGDKEQLRPSFLLSSLRPSLTGARRL Prediction: +-+++++++++++++-+-------+-------+++--+++-+--------+-+-+--++- Confidence: 724445668999769242247324653323464554286556525732267252625767 Sequence: VETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVT Prediction: -------++-+++++-++-++-+-++---+-------------------------+---+ Confidence: 754876557455646289359252753364797979984452552677823244676564 Sequence: PAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGS Prediction: -------+-+++-+-----------++--+--+-++++-------+---++------+-+ Confidence: 366332582755244443454323375745555445543282889754955883345526 Sequence: RHNERRFLRNTKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEI Prediction: ++++++--++-++--+--+--+--------+---+-----++------------+-+--- Confidence: 956587238526645555534763834835463946563857223345835432575778 Sequence: LAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRE Prediction: -----------------+--------+--+-+-----+--+++--+---+++-++----- Confidence: 996997799597997995469384534425364455242547673724785446972725 Sequence: LSEAEVRQHREARPALLTSRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKA Prediction: ------+--+--+----+-+-+---+----+-----------+++++++++++-+++-+- Confidence: 944536622724823346287737453436768969937764886886895692857764 Sequence: LFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTI Prediction: -------++-++------------------+----+-+-+---------+---+------ Confidence: 863684269398242556388877784283625777777533356837959774463525 Sequence: PQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHL Prediction: ---+---------+---++--++--------+---++--+++-----------+------ Confidence: 437583499937853227726743667326553268644644522734625385499949 Sequence: QETSPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTL Prediction: ------+---------+-++-++---------------+-+-+++-+-------+--+-- Confidence: 542347669989743252755557776999399965678582657644356334467428 Sequence: LCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNL Prediction: -----------------++------------------+--+---+---+----------- Confidence: 963872557744953376563578399999999474752762578369837665775739 Sequence: RKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTF Prediction: ++---+-------------------------------++-+-++-++++-+++-+-+--- Confidence: 552684779899775526583879588887999886364274744677639775835537 Sequence: NRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLP Prediction: -+--+-++++++------+-+-----------+-++--+-----------+--------- Confidence: 374282797597274468765542889694834755755393399883835846899487 Sequence: FHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLL Prediction: -----------------------+---+-+----+---+----+--+------------- Confidence: 873474255277628936362774368466232364347332245354894799899888 Sequence: KLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTILD Prediction: +--+-+--+-----+-++-+++-+++-++----------------------- Confidence: 5626366259466446972688358725522726857673365324624898 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|O14746|TERT_HUMAN Telomerase reverse transcriptase OS=Homo sapiens GN=TERT PE=1 SV=1 Sequence: MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPW Prediction: --+--+-+------+-----------------++--+------+---+------------ Confidence: 117515263612686112138779676922625632488549432444258549653865 Sequence: DARPPPAAPSFRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVR Prediction: --------------------------+---++-++------------------------- Confidence: 653584885462122342679837824432752654122867775964685648451284 Sequence: SYLPNTVTDALRGSGAWGLLLRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGA Prediction: ----------------------+---------------------+--------------- Confidence: 329747988882412636888647377679798839585958955355253122727997 Sequence: ATQARPPPHASGPRRRLGCERAWNHSVREAGVPLGLPAPGARRRGGSASRSLPLPKRPRR Prediction: ----++++++++++++-+-++-+++++---------+++++++++++--+---+++++++ Confidence: 622284466566355524147164354165676442347769976554163315858576 Sequence: GAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAEEATSLEGALSGTRHSHPSVG Prediction: -------+-+-----+-+-+++--------------+------------+-+-------- Confidence: 355622141332132515245512324376564435357466865344343523214123 Sequence: RQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGDKEQLRPSFLLSSLRPSLTGARRL Prediction: --++---++++-++----------+--+++--+-+--+++-++-+--+--+-+------- Confidence: 224421244641432235664424433443434133144714313324144232226459 Sequence: VETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVT Prediction: ----------------++-+++++++++------------++--+-+--++--------- Confidence: 879989965845462248269469644463459658741357224235943242226436 Sequence: PAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGS Prediction: -------+-------------------------------------+-------------+ Confidence: 887564243224625764577457726784995444624362279477934984884424 Sequence: RHNERRFLRNTKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEI Prediction: ++-+++--++-----+---+-+----------------+----------+-+-++----- Confidence: 541444344462636341246545944772261522544723544241252423333498 Sequence: LAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRE Prediction: -----------------+------------------++--++---+---+---+------ Confidence: 899796799788884874338183623552322424444633174345753183267889 Sequence: LSEAEVRQHREARPALLTSRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKA Prediction: ------++-+---------+-+--++-++-++--+--+----+---+-++-++-++---- Confidence: 847613441545255542264813481744733343141223512142463582663814 Sequence: LFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTI Prediction: -----+--+-++-+-----------------------+-----------+----+---+- Confidence: 713674267153332555245534241245263853752234453524849262423463 Sequence: PQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHL Prediction: ------------------------------++-+-++-+++------------------- Confidence: 234147379678848535279121476324361636733532656967885493899989 Sequence: QETSPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTL Prediction: ------+------+--------------------------------------+-+----- Confidence: 787235346738444325253359969999878634761822111413412232428328 Sequence: LCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNL Prediction: ----------------------------------------------------------+- Confidence: 987875769769977786255689248489999852624935992786357345581647 Sequence: RKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTF Prediction: --------------------------------------+---+---+-----------+- Confidence: 311374688798686424643778767852857662824322523142424867272445 Sequence: NRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLP Prediction: -+--+-+++--++-------+--------+------------------------------ Confidence: 132331477234485438366524677573512522857183599774953736585742 Sequence: FHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLL Prediction: ---+-+--------------+---+--+-+------------------------------ Confidence: 332543332357539925693282446527122227324442466377898898448586 Sequence: KLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTILD Prediction: --++++-+--------+----+-++-----+--------------------- Confidence: 1747662425478457423225336233143623857598423437646786 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>O14746|TERT Sequence: MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPW Prediction: +++++++++++++-++-----------------------+-------------------- Confidence: 788999788557536534430241221012000111401513434224200421000012 Sequence: DARPPPAAPSFRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVR Prediction: --------------++-+----+-------+++++++++++------------------- Confidence: 112101100104425536342453143133787878778563231001000101000000 Sequence: SYLPNTVTDALRGSGAWGLLLRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGA Prediction: ----------------------------------------------------+------- Confidence: 130241112002230022002030012000101113101110124432212284033010 Sequence: ATQARPPPHASGPRRRLGCERAWNHSVREAGVPLGLPAPGARRRGGSASRSLPLPKRPRR Prediction: ----+--+--++-++++++++++++++++++++++-+++++++++++++++-++++++++ Confidence: 010154354456378777777886686665586874679889998865667468879655 Sequence: GAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAEEATSLEGALSGTRHSHPSVG Prediction: ----++-++++++++++++++++----+--------------------+---+------- Confidence: 433376458656865888787653333542313332210200022131531154232123 Sequence: RQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGDKEQLRPSFLLSSLRPSLTGARRL Prediction: --++--++--------------+-+-++++-++++++++++++++++++--++-++-++- Confidence: 225544551332221242124374535578458756787977688658923862764652 Sequence: VETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVT Prediction: --------+-------++++++++++++-+++--+--++-+++++++--+++++------ Confidence: 120010025210312378899999989826861372369499587784399866332312 Sequence: PAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGS Prediction: --------------------------------------++--++-+----+---++++++ Confidence: 112100121011001000000000022001101120126511661621046004655878 Sequence: RHNERRFLRNTKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEI Prediction: +++++++-++-+++++++++-+++--+---+---------+-+-++++++--+++---+- Confidence: 799656548727856767884756145104501122242352646575564356523351 Sequence: LAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRE Prediction: -----------------+--+---------+--+--+++-++------------------ Confidence: 013101200010014027425401442133742632675456411121013101111140 Sequence: LSEAEVRQHREARPALLTSRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKA Prediction: -------+----+++--+++-+---+-++++++-++++++++++++++-+-++++++-+- Confidence: 131141154444876237563813454976877385899857857675463875778374 Sequence: LFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTI Prediction: -++--+----------+-+---+-----+-++-----+-+--+++------+-+++++++ Confidence: 165006213321433164612453222353752333254534755342133528877596 Sequence: PQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHL Prediction: ++++-----------------+++-----+++++++++++++--+--------------- Confidence: 897821310010002112442676212446878878999888135014111311200010 Sequence: QETSPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTL Prediction: --------------------------------------+-+++++++-++++++++-++- Confidence: 000132431000011123111121010201220032417256757674888899973861 Sequence: LCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNL Prediction: ------------------------+---------------------------------+- Confidence: 000000000000000003313200520021000013121002000101311131112152 Sequence: RKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTF Prediction: -+--------------------------++-+---+--+---+--++-----+-+++-+- Confidence: 251104100100110121011011334256253415135321624554243472576354 Sequence: NRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLP Prediction: +++++++++++++--------------+++-+++++--++-------------------+ Confidence: 678887899868920441134244211668476667317814431213032122321345 Sequence: FHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLL Prediction: -++++++++++--+----------+--+++----------------+++--+---++--+ Confidence: 378876776762472333004203732878443221122323122356503543475425 Sequence: KLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTILD Prediction: ++++++++++++++++++++++-++++-+++--------++++++--++---- Confidence: 88899999999888977765882588547652120223277786732751130 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPW Prediction: --++-+++--+-----+-----------++-++++++--++-+++--+------------ Confidence: 124425762152112142100020010047339759721443553006101020000000 Sequence: DARPPPAAPSFRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVR Prediction: -------------------------++-+++-----------------+-+++------- Confidence: 000101020200001102110012058334830220011000000032337442100001 Sequence: SYLPNTVTDALRGSGAWGLLLRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGA Prediction: -------------++---++-++-----------+------------------------- Confidence: 200020000002135133340352002000100140000000000000000013010000 Sequence: ATQARPPPHASGPRRRLGCERAWNHSVREAGVPLGLPAPGARRRGGSASRSLPLPKRPRR Prediction: -------++++++++++++++++++++++++--+++++++++++++++++-++--++-++ Confidence: 000011245346336766567497645554422445557547645653542352246244 Sequence: GAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAEEATSLEGALSGTRHSHPSVG Prediction: ++-+---+----+--++++++-+-+-+++---+------------------++++-+--+ Confidence: 353321130312523453456242404541104301100010001011002455424324 Sequence: RQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGDKEQLRPSFLLSSLRPSLTGARRL Prediction: +--++-+++----+------------------++++-----+----------++++-++- Confidence: 533533665222033201000000100010014554213004211000000234352440 Sequence: VETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVT Prediction: -------------+++++--++++++--------+---++----+++--++++------- Confidence: 000011101011235366336358732101123051004411005571284541012112 Sequence: PAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGS Prediction: -----------------------------+--++++--+---+---+----------++- Confidence: 110110010110123111001001122105005344224102300032000002103742 Sequence: RHNERRFLRNTKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEI Prediction: ++++++--++------------------------+++++++-+++--+-+-+-+------ Confidence: 566569304720110010110000000000003256455431353234363316200001 Sequence: LAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRE Prediction: -----------------------+----------+-++---------------------- Confidence: 000000000010000003000103110002300242542300001011000000000000 Sequence: LSEAEVRQHREARPALLTSRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKA Prediction: ------------+--+-+-+-+-++++++++--+++++++++++-++++++++--+---- Confidence: 000211002102420314340604698676923454667557753665683562243121 Sequence: LFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTI Prediction: ----------++-+++-+-----------------+++-----+++++-+---+++++-- Confidence: 101002321254143504102100000100002008552122276866061208547430 Sequence: PQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHL Prediction: ------+---+----------+--+--+++-+++-++++++------------------- Confidence: 000100601331013100100313511386344635753543111000002000000010 Sequence: QETSPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTL Prediction: ---------------++++++++----------++---+-+++--++++++++++----- Confidence: 110000000000002356454440002000002450004156930458753446500000 Sequence: LCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNL Prediction: ------------------------+------------++------+------+++++--- Confidence: 000000000000000123301000400000000011043022001402012344554010 Sequence: RKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTF Prediction: -+---+-------------------------------+------------+--+---+++ Confidence: 252004112301001020220100010010010300040001301023233125313444 Sequence: NRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLP Prediction: +++-++++++-++-------+---+--+--+++-++-+++-------+-----------+ Confidence: 443365465435622220004102300532333236044613000024123000000014 Sequence: FHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLL Prediction: ------+--+-+--------+--+-----++-+++++----------------------- Confidence: 011011331323130000024333000304414444321000001120000000300000 Sequence: KLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTILD Prediction: ---+---------++++---+---+--------------------------- Confidence: 1024221031002344432051004111001100001000000200030000 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.