Detail

Detail-Interactions:
RAID ID:	RPI00001613
RNA/Protein Symbol 1:	TERC(htr)
RNA/Protein Category 1:	snoRNA
RNA/Protein Symbol 2:	PNN
RNA/Protein Category 2:	Protein
Validated Method:	quantitative fluorescent reverse transcription polymerase chain reaction
Tissue:	bladder cancer cell line biu-102
PMID:	20556588
Detail description:	The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

Detail-Interactions:

RAID ID:

RPI00001613

RNA/Protein Symbol 1:

TERC(htr)

RNA/Protein Category 1:

snoRNA

RNA/Protein Symbol 2:

PNN

RNA/Protein Category 2:

Protein

Validated Method:

quantitative fluorescent reverse transcription polymerase chain reaction

Tissue:

bladder cancer cell line biu-102

PMID:

20556588

Detail description:

The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

>sp|Q9H307|PININ_HUMAN Pinin OS=Homo sapiens GN=PNN PE=1 SV=4 Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: -----++------+-+---+------++-+-+--+--+--+-+------+++++++-+-- Confidence: 978787453426546733553744466645374253673757478572368889592725 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -++--+++-++++++-+--+---++++++++++++++++++------++---+-+---++ Confidence: 867235652469858264544655845689999989975445644465522452544288 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: ++++++---------+++++++++-------+-++-+--++--+++++++++-------+ Confidence: 999788245276443477989887745897656462524552278998986543449574 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ----++--++-++------+-+++--+-----------------------++-++++++- Confidence: 533366228645554335274784276765649566384565565472665437785652 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: ------+--+----------+--------++--------+-++++++++++-+-----+- Confidence: 662957554553326634327252536466474576593536496898868245326673 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: --++------+--++-------------------------------++--+--------- Confidence: 235752233463344575755332332696976865766389678344426334324334 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ------------+++++++++----------------------------+--+-+---+- Confidence: 553838876448756466645256699999999889359999978634286345442242 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: -++----------------++-++-+---------+----+--+-+----------++++ Confidence: 445584689998986723365264263262554645433252352524254454236556 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: +-+-+-+++-------+++++-------------+-+------------------+---- Confidence: 525444455222452265565434748978342344526473544622642653858439 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: ----------++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 697698262249899999999999999999999999999999999999899999999999 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++- Confidence: 999999999999999999999989989999999999999999999899979999978873 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: +++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 697899999898989978999999999987678789999999999989988999999 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>sp|Q9H307|PININ_HUMAN Pinin OS=Homo sapiens GN=PNN PE=1 SV=4 Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: -----+-------+-+-+-+----+-++-+-+-++--+--+------+-++++++++++- Confidence: 545486343427634543351452567625172371381445168443168889794732 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -++--++++++++++++-------++-+++++++-++----------++----------- Confidence: 764245434558747373722572631459888914515377735353422626477632 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: +-+------------+++++++++---------------------+-+++---------- Confidence: 636321657273123356758574644675438114457438613615453567658874 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ----+----+-++------+-++----------------------------+-+-+---- Confidence: 664551221453463347156434673786559858587773263373771345242222 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: ------+-----------------------+--------------++------------- Confidence: 662866453135447776561754858793386596384321211361222646246714 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: ------------------------------------------------------------ Confidence: 665599997567633987787551432685666976988899999445772747875447 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ------------+---++------------------------------------------ Confidence: 888977987787452263142238896899879888658989998998529979554545 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: ------------------------------------------------------------ Confidence: 886888699899997848977877544253797785755746415376587566342422 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: ----------------------------------------------+--------+---- Confidence: 353635245464855443777679949989996766365245632341322662538276 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: -----------------++-++--+-+--+-+++-++-----+--+-+-+++---+--++ Confidence: 599676574341212224313411465313253326311216324344243342242246 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: +++++++-----------+-----------+++++--+-+++-++++++----+----+- Confidence: 586776621153233521514236552423435541151346165355421226142145 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: -++++++++--++-+++++-+++++++++----+++++++++++++-++++++++++ Confidence: 163653454223714644726568436552321446346765853437564877799 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>Q9H307|PNN Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: ------------------------+-++-++++++++++-+++------++++++++++- Confidence: 112100100000120331023134716725595786697467843444376678765553 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -+--------++++++++-+---++-----------------------------+---+- Confidence: 363112133368888876353305711122200000000000000001142134733453 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: +-+-+-----------+-+++++++++++-++-++--++--------------------- Confidence: 645364202112213264679799668854883682256002122411430113440214 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ------------------++-+----++++++----------------------++-+++ Confidence: 321231324234411122563534337775771311101000011012001314752677 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: -++++-+----------------------------------------------------- Confidence: 267553744111001002220000000012100000000000011101000000000000 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: ------------------------------------------------------------ Confidence: 000000000000010000000000000000000000000000000000000000000000 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: ------------------------------------------------------------ Confidence: 001000000000020020000000000000000000000000000000000000000000 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000010100 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: -----------------++++++++++++-++-++++-+--------------------- Confidence: 101221214131132248889999989774664777535332423211110001000102 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: +-++---+-------------+-+++++++++++++++++++++++-++-+++-+----- Confidence: 635742352443332112312535755757898999997868758837736774533312 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: ------------+-------------------------++++-+++-++--+--+++- Confidence: 2312311323326003111323434234211220143156554556375246235570 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: -----+------------------+--+-++++++++++-+----++++++++++++++- Confidence: 233224010000000121223211403334364786364141201345798898796852 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -++---+++++++-+-++-+++--++++++++++++++--------------------+- Confidence: 045330446776824343144423745678969984751321011200121031112242 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: +-+-++-+-----+-+++++++++++----++-----------+++-+++-+-------- Confidence: 414353240102233484557477543301443200000013343424451322030000 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ----+-------------++--+++----------------------------+-+---- Confidence: 000143310002201200550334413101000000001100011202102104240020 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: ------+-----------------------------+----++++++++++-+-----++ Confidence: 001103311210330001003332200003000002412233455876545342322133 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: +-++--+---+---------------------------------------+--------- Confidence: 334412533253011001012202011202000000000000000221123220100020 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ---------------++--+-----------------------------------+---- Confidence: 101010000000311442231010000000000000000000000000020222233232 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: ---------------------+-++----------------------------------- Confidence: 022000000000000011212413432210001011100111010000200000002220 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: ------------------------------------------------------------ Confidence: 221010010000002011100000000000000000010120100000000000000000 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: ------------++++++++++++++++++++++++++++++++-------+++-+++++ Confidence: 100000001122546695979899989999897968666655433332233343353445 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: ++-+-++++++++++++-+--++--+++-+++++++++++++++++++++++++++++++ Confidence: 443534444455334443423443354435584969999999999999886997965666 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: +++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 576577799987976986889689558697786679679998998979778767576 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest).

The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.

The Predicated Binding Sites between TERC and PNN
By miRanda	Structure	Match Score	Energy Score	TERC Location	PNN Location

The Predicated Binding Sites between TERC and PNN
By RIsearch	Structure	TERC Location	PNN Location	Score

The Predicated Binding Sites of PNN
RBPBD
RsiteDB
BindN	>sp\|Q9H307\|PININ_HUMAN Pinin OS=Homo sapiens GN=PNN PE=1 SV=4 Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: -----++------+-+---+------++-+-+--+--+--+-+------+++++++-+-- Confidence: 978787453426546733553744466645374253673757478572368889592725 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -++--+++-++++++-+--+---++++++++++++++++++------++---+-+---++ Confidence: 867235652469858264544655845689999989975445644465522452544288 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: ++++++---------+++++++++-------+-++-+--++--+++++++++-------+ Confidence: 999788245276443477989887745897656462524552278998986543449574 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ----++--++-++------+-+++--+-----------------------++-++++++- Confidence: 533366228645554335274784276765649566384565565472665437785652 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: ------+--+----------+--------++--------+-++++++++++-+-----+- Confidence: 662957554553326634327252536466474576593536496898868245326673 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: --++------+--++-------------------------------++--+--------- Confidence: 235752233463344575755332332696976865766389678344426334324334 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ------------+++++++++----------------------------+--+-+---+- Confidence: 553838876448756466645256699999999889359999978634286345442242 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: -++----------------++-++-+---------+----+--+-+----------++++ Confidence: 445584689998986723365264263262554645433252352524254454236556 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: +-+-+-+++-------+++++-------------+-+------------------+---- Confidence: 525444455222452265565434748978342344526473544622642653858439 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: ----------++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 697698262249899999999999999999999999999999999999899999999999 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++- Confidence: 999999999999999999999989989999999999999999999899979999978873 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: +++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 697899999898989978999999999987678789999999999989988999999 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
BindN+	>sp\|Q9H307\|PININ_HUMAN Pinin OS=Homo sapiens GN=PNN PE=1 SV=4 Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: -----+-------+-+-+-+----+-++-+-+-++--+--+------+-++++++++++- Confidence: 545486343427634543351452567625172371381445168443168889794732 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -++--++++++++++++-------++-+++++++-++----------++----------- Confidence: 764245434558747373722572631459888914515377735353422626477632 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: +-+------------+++++++++---------------------+-+++---------- Confidence: 636321657273123356758574644675438114457438613615453567658874 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ----+----+-++------+-++----------------------------+-+-+---- Confidence: 664551221453463347156434673786559858587773263373771345242222 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: ------+-----------------------+--------------++------------- Confidence: 662866453135447776561754858793386596384321211361222646246714 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: ------------------------------------------------------------ Confidence: 665599997567633987787551432685666976988899999445772747875447 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ------------+---++------------------------------------------ Confidence: 888977987787452263142238896899879888658989998998529979554545 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: ------------------------------------------------------------ Confidence: 886888699899997848977877544253797785755746415376587566342422 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: ----------------------------------------------+--------+---- Confidence: 353635245464855443777679949989996766365245632341322662538276 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: -----------------++-++--+-+--+-+++-++-----+--+-+-+++---+--++ Confidence: 599676574341212224313411465313253326311216324344243342242246 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: +++++++-----------+-----------+++++--+-+++-++++++----+----+- Confidence: 586776621153233521514236552423435541151346165355421226142145 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: -++++++++--++-+++++-+++++++++----+++++++++++++-++++++++++ Confidence: 163653454223714644726568436552321446346765853437564877799 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
RNAbindR	>Q9H307\|PNN Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: ------------------------+-++-++++++++++-+++------++++++++++- Confidence: 112100100000120331023134716725595786697467843444376678765553 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -+--------++++++++-+---++-----------------------------+---+- Confidence: 363112133368888876353305711122200000000000000001142134733453 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: +-+-+-----------+-+++++++++++-++-++--++--------------------- Confidence: 645364202112213264679799668854883682256002122411430113440214 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ------------------++-+----++++++----------------------++-+++ Confidence: 321231324234411122563534337775771311101000011012001314752677 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: -++++-+----------------------------------------------------- Confidence: 267553744111001002220000000012100000000000011101000000000000 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: ------------------------------------------------------------ Confidence: 000000000000010000000000000000000000000000000000000000000000 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: ------------------------------------------------------------ Confidence: 001000000000020020000000000000000000000000000000000000000000 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000010100 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: -----------------++++++++++++-++-++++-+--------------------- Confidence: 101221214131132248889999989774664777535332423211110001000102 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: +-++---+-------------+-+++++++++++++++++++++++-++-+++-+----- Confidence: 635742352443332112312535755757898999997868758837736774533312 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: ------------+-------------------------++++-+++-++--+--+++- Confidence: 2312311323326003111323434234211220143156554556375246235570 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
Pprint	Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL Prediction: -----+------------------+--+-++++++++++-+----++++++++++++++- Confidence: 233224010000000121223211403334364786364141201345798898796852 Sequence: LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS Prediction: -++---+++++++-+-++-+++--++++++++++++++--------------------+- Confidence: 045330446776824343144423745678969984751321011200121031112242 Sequence: KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ Prediction: +-+-++-+-----+-+++++++++++----++-----------+++-+++-+-------- Confidence: 414353240102233484557477543301443200000013343424451322030000 Sequence: AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH Prediction: ----+-------------++--+++----------------------------+-+---- Confidence: 000143310002201200550334413101000000001100011202102104240020 Sequence: LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN Prediction: ------+-----------------------------+----++++++++++-+-----++ Confidence: 001103311210330001003332200003000002412233455876545342322133 Sequence: EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ Prediction: +-++--+---+---------------------------------------+--------- Confidence: 334412533253011001012202011202000000000000000221123220100020 Sequence: EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE Prediction: ---------------++--+-----------------------------------+---- Confidence: 101010000000311442231010000000000000000000000000020222233232 Sequence: ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS Prediction: ---------------------+-++----------------------------------- Confidence: 022000000000000011212413432210001011100111010000200000002220 Sequence: QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV Prediction: ------------------------------------------------------------ Confidence: 221010010000002011100000000000000000010120100000000000000000 Sequence: PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS Prediction: ------------++++++++++++++++++++++++++++++++-------+++-+++++ Confidence: 100000001122546695979899989999897968666655433332233343353445 Sequence: SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL Prediction: ++-+-++++++++++++-+--++--+++-+++++++++++++++++++++++++++++++ Confidence: 443534444455334443423443354435584969999999999999886997965666 Sequence: ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR Prediction: +++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 576577799987976986889689558697786679679998998979778767576 *Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *Confidence: from level 0 (lowest) to level 9 (highest).

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RAID

The Detail Information for This Interaction