Detail

Detail-Interactions:
RAID ID:	RPI00001608
RNA/Protein Symbol 1:	TERC(htr)
RNA/Protein Category 1:	snoRNA
RNA/Protein Symbol 2:	MTA1
RNA/Protein Category 2:	Protein
Validated Method:	quantitative fluorescent reverse transcription polymerase chain reaction
Tissue:	bladder cancer cell line biu-97
PMID:	20556588
Detail description:	The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

Detail-Interactions:

RAID ID:

RPI00001608

RNA/Protein Symbol 1:

TERC(htr)

RNA/Protein Category 1:

snoRNA

RNA/Protein Symbol 2:

MTA1

RNA/Protein Category 2:

Protein

Validated Method:

quantitative fluorescent reverse transcription polymerase chain reaction

Tissue:

bladder cancer cell line biu-97

PMID:

20556588

Detail description:

The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

>sp|Q13330|MTA1_HUMAN Metastasis-associated protein MTA1 OS=Homo sapiens GN=MTA1 PE=1 SV=2 Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: ------+---------++++++--+------+--+-+---------++++-++------- Confidence: 877383686539384256657758539736252352764628745355752752885687 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: ---+-----+-----------------------------+++-+-----------+---- Confidence: 236562762554223225256597889879889797426655565347584237457352 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: +-+-+----------+-+++--+--------------+---------+--++-------- Confidence: 558364252684523537777648978968993332343546324248335622457358 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: --------+-+++--+---------+-----------+---+--+----+++-++-+--- Confidence: 925632326247852539458444644349849999952536586564466839625635 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: -----++-------------------+--------------+------------------ Confidence: 344445757399698748424836924872569427525665877658483484998998 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: ----+-------------------------+---++-++++-+-++-+++-++-+--+++ Confidence: 543556626966979764272259854473522378356576724545566657462556 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: ++++++-+----+----+-+-+++++++--+---+-+++++++-----------+----- Confidence: 857555646226655474462584788622843244645656532236332526687426 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: --+--++---+--++---+++++++++-++---+-++++++++--+-++--+--+-+-++ Confidence: 325324532273258322597877968254222549897658523637553573427679 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: --++--+---+-----+--+----+---+-----+-----------+---++------+- Confidence: 458767838958425475456483645675332676326222268762468458368953 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: --++++++++++-+--++--++-+--+--------+-++--++++-+------+-+++-- Confidence: 545648658546362666554455465863663346265237867242366226255644 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: ---+---++-+-++++--+------++++++-+--+--+-++-++++--+---------- Confidence: 342744365365754522625342486988756348536278288774258799999849 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: ----+++-++--+++++++++++++++---+--+--+-+--++------------ Confidence: 6252677598366886699679957765375325325272254427488899999 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>sp|Q13330|MTA1_HUMAN Metastasis-associated protein MTA1 OS=Homo sapiens GN=MTA1 PE=1 SV=2 Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: ---+-++-----+-----+--+--++--------+-+---------+------------- Confidence: 435463673327395532322448447665224244476939533434478436776762 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: +-------------------------------------++++-+---------------- Confidence: 425287888687567657676899998877579672223555262327456338849571 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: --+-+------------------------------------------+--+--------- Confidence: 384245163674784483759849858986551625634775643555323254689597 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: -------------------------------------+---------------------- Confidence: 979676782757398688487747879989988959935562793798853761765788 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: --------------------------------------+--------------------- Confidence: 676686378699699898544434622684678315323551857874297784866347 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: ----+--+---------++----------++-+-++-++++++----------------- Confidence: 422353143532334124433566683144313366156683411134227659584121 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: +--------------------------------------+++++-++++-+--------- Confidence: 442532877754277898989966565345132223221365451433424325162213 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: --+-+++--++---+----+--+-+++-+-+--+-++++++++--++++------++-++ Confidence: 114254612442324645641141664442533418857757612747472161235388 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: --++--+---++++++++----------+-----+----++----++++++-+------- Confidence: 127724633563996897113482326736652445213431221356436234579977 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: -----+-++----+---+----------------+++++++++++-+-----++++++-- Confidence: 776434247212251314774775874852433135455445857244146144555623 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: ---+---++-+-++----+----+-++--++-+--+-+++++-++++-++---------- Confidence: 323454535144342223433234344127455348436456165863545366446457 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: ----+++-++---+---++-+++++++---+--+-------+------------- Confidence: 7243494587551322279169867543253234666613431315248488984 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>Q13330|MTA1 Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: ------+-------------+++--+-+--+--++-+------++-+-----+------- Confidence: 103202601110111244445652470512523584721140265353410252203111 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: ------------------------------------------------------------ Confidence: 100000000000000000000000000000000000000010012220101300000000 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: ----+-------------------------------------+------++++------- Confidence: 203352424202101000000000000000000111221011544414456563110100 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: ----------------------+--------------+-++-+-+--------------- Confidence: 011012212121100010111263131140102224284664536332111000000000 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: -----------------------+------+---+----------------------+-- Confidence: 000000000000000000022225144312523151220001000101103213210511 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: ----++-+------------------++--------+++++++++-+--+---------- Confidence: 433375363334312334321001125524344423567998968484451331101101 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: ----------------------------------+------++-++-++++-++++++++ Confidence: 111000000000000000000000000011422452121225726646657478657757 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: +-+-+++++++++-+--------------------+++++++++++++++++++-++-++ Confidence: 746486885577525122111211102021312436676879988899988777499379 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: --++-+++--+++++++++---------------------------++--++-------- Confidence: 349936754277898889733433232012002122231111013386248541232011 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: ---------+--------------------------------+----------------- Confidence: 001214223511032023001111232011113210021131711210200102000110 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: -----------------------+--------+-++++++++++++--+----------- Confidence: 101011121000020110132315441000305369688867678831631411320121 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: -----++-+++-+++--++-+++++++---+-------++---------------- Confidence: 01211851775356644883698567624371223132552312313112000110 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: --------------+-++++++-----+---++++++---+--+--+++----------- Confidence: 313200301213003235356521200321379554632140233176421110012002 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: --------------------------------------+-----+--------------- Confidence: 321002222222221221000100000000100000233332123210210100000111 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: --+----------------------------------------------+++-+------ Confidence: 304010100000000102010010000000001000000000020002254434010000 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: --------+---+--------+++-------------+--++--+--+++++--+---+- Confidence: 000010223320410020102444100000000100240354204225465422323342 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: +---------------------+------------------------------------- Confidence: 420001110000000010010030112010000000000000000000000000000000 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: --------+----------------------+-+-+-+-++-+++--+------+----- Confidence: 011021104003100210000000000000252434333763555324210030330132 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: -++-++----+-+-+-------+-------+-------------------------+--- Confidence: 245344001241325012100233232201403203100220123232310002004000 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: ---+-+++-++++++----++++++++-----+--+-+++++++---------------+ Confidence: 102335762574734110235474664122234115355745440002000001002037 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: +-++--+---+-++-++-----------------------+-+++-++--+++------- Confidence: 416722521351442443221300030011301032000042544243334330200010 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: -----+--------------------------+++-+-+--++++-+++++++----+-- Confidence: 000113213222131211001100012032324453524123535356775332003411 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: ---+-+-+----+++-+++----------------++++++++++++---+-+------- Confidence: 011434231232444344322102232211223214577776455751023231200000 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: ----++--++-+++++-++-+++++++---+-------+---------------- Confidence: 0110552054333444376246756462223000000040000000000000000 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest).

The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.

The Predicated Binding Sites between TERC and MTA1
By miRanda	Structure	Match Score	Energy Score	TERC Location	MTA1 Location

The Predicated Binding Sites between TERC and MTA1
By RIsearch	Structure	TERC Location	MTA1 Location	Score

The Predicated Binding Sites of MTA1
RBPBD
RsiteDB
BindN	>sp\|Q13330\|MTA1_HUMAN Metastasis-associated protein MTA1 OS=Homo sapiens GN=MTA1 PE=1 SV=2 Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: ------+---------++++++--+------+--+-+---------++++-++------- Confidence: 877383686539384256657758539736252352764628745355752752885687 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: ---+-----+-----------------------------+++-+-----------+---- Confidence: 236562762554223225256597889879889797426655565347584237457352 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: +-+-+----------+-+++--+--------------+---------+--++-------- Confidence: 558364252684523537777648978968993332343546324248335622457358 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: --------+-+++--+---------+-----------+---+--+----+++-++-+--- Confidence: 925632326247852539458444644349849999952536586564466839625635 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: -----++-------------------+--------------+------------------ Confidence: 344445757399698748424836924872569427525665877658483484998998 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: ----+-------------------------+---++-++++-+-++-+++-++-+--+++ Confidence: 543556626966979764272259854473522378356576724545566657462556 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: ++++++-+----+----+-+-+++++++--+---+-+++++++-----------+----- Confidence: 857555646226655474462584788622843244645656532236332526687426 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: --+--++---+--++---+++++++++-++---+-++++++++--+-++--+--+-+-++ Confidence: 325324532273258322597877968254222549897658523637553573427679 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: --++--+---+-----+--+----+---+-----+-----------+---++------+- Confidence: 458767838958425475456483645675332676326222268762468458368953 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: --++++++++++-+--++--++-+--+--------+-++--++++-+------+-+++-- Confidence: 545648658546362666554455465863663346265237867242366226255644 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: ---+---++-+-++++--+------++++++-+--+--+-++-++++--+---------- Confidence: 342744365365754522625342486988756348536278288774258799999849 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: ----+++-++--+++++++++++++++---+--+--+-+--++------------ Confidence: 6252677598366886699679957765375325325272254427488899999 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
BindN+	>sp\|Q13330\|MTA1_HUMAN Metastasis-associated protein MTA1 OS=Homo sapiens GN=MTA1 PE=1 SV=2 Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: ---+-++-----+-----+--+--++--------+-+---------+------------- Confidence: 435463673327395532322448447665224244476939533434478436776762 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: +-------------------------------------++++-+---------------- Confidence: 425287888687567657676899998877579672223555262327456338849571 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: --+-+------------------------------------------+--+--------- Confidence: 384245163674784483759849858986551625634775643555323254689597 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: -------------------------------------+---------------------- Confidence: 979676782757398688487747879989988959935562793798853761765788 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: --------------------------------------+--------------------- Confidence: 676686378699699898544434622684678315323551857874297784866347 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: ----+--+---------++----------++-+-++-++++++----------------- Confidence: 422353143532334124433566683144313366156683411134227659584121 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: +--------------------------------------+++++-++++-+--------- Confidence: 442532877754277898989966565345132223221365451433424325162213 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: --+-+++--++---+----+--+-+++-+-+--+-++++++++--++++------++-++ Confidence: 114254612442324645641141664442533418857757612747472161235388 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: --++--+---++++++++----------+-----+----++----++++++-+------- Confidence: 127724633563996897113482326736652445213431221356436234579977 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: -----+-++----+---+----------------+++++++++++-+-----++++++-- Confidence: 776434247212251314774775874852433135455445857244146144555623 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: ---+---++-+-++----+----+-++--++-+--+-+++++-++++-++---------- Confidence: 323454535144342223433234344127455348436456165863545366446457 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: ----+++-++---+---++-+++++++---+--+-------+------------- Confidence: 7243494587551322279169867543253234666613431315248488984 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
RNAbindR	>Q13330\|MTA1 Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: ------+-------------+++--+-+--+--++-+------++-+-----+------- Confidence: 103202601110111244445652470512523584721140265353410252203111 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: ------------------------------------------------------------ Confidence: 100000000000000000000000000000000000000010012220101300000000 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: ----+-------------------------------------+------++++------- Confidence: 203352424202101000000000000000000111221011544414456563110100 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: ----------------------+--------------+-++-+-+--------------- Confidence: 011012212121100010111263131140102224284664536332111000000000 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: -----------------------+------+---+----------------------+-- Confidence: 000000000000000000022225144312523151220001000101103213210511 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: ----++-+------------------++--------+++++++++-+--+---------- Confidence: 433375363334312334321001125524344423567998968484451331101101 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: ----------------------------------+------++-++-++++-++++++++ Confidence: 111000000000000000000000000011422452121225726646657478657757 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: +-+-+++++++++-+--------------------+++++++++++++++++++-++-++ Confidence: 746486885577525122111211102021312436676879988899988777499379 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: --++-+++--+++++++++---------------------------++--++-------- Confidence: 349936754277898889733433232012002122231111013386248541232011 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: ---------+--------------------------------+----------------- Confidence: 001214223511032023001111232011113210021131711210200102000110 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: -----------------------+--------+-++++++++++++--+----------- Confidence: 101011121000020110132315441000305369688867678831631411320121 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: -----++-+++-+++--++-+++++++---+-------++---------------- Confidence: 01211851775356644883698567624371223132552312313112000110 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
Pprint	Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD Prediction: --------------+-++++++-----+---++++++---+--+--+++----------- Confidence: 313200301213003235356521200321379554632140233176421110012002 Sequence: KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT Prediction: --------------------------------------+-----+--------------- Confidence: 321002222222221221000100000000100000233332123210210100000111 Sequence: HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL Prediction: --+----------------------------------------------+++-+------ Confidence: 304010100000000102010010000000001000000000020002254434010000 Sequence: LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM Prediction: --------+---+--------+++-------------+--++--+--+++++--+---+- Confidence: 000010223320410020102444100000000100240354204225465422323342 Sequence: SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL Prediction: +---------------------+------------------------------------- Confidence: 420001110000000010010030112010000000000000000000000000000000 Sequence: EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN Prediction: --------+----------------------+-+-+-+-++-+++--+------+----- Confidence: 011021104003100210000000000000252434333763555324210030330132 Sequence: KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC Prediction: -++-++----+-+-+-------+-------+-------------------------+--- Confidence: 245344001241325012100233232201403203100220123232310002004000 Sequence: WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR Prediction: ---+-+++-++++++----++++++++-----+--+-+++++++---------------+ Confidence: 102335762574734110235474664122234115355745440002000001002037 Sequence: IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY Prediction: +-++--+---+-++-++-----------------------+-+++-++--+++------- Confidence: 416722521351442443221300030011301032000042544243334330200010 Sequence: LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL Prediction: -----+--------------------------+++-+-+--++++-+++++++----+-- Confidence: 000113213222131211001100012032324453524123535356775332003411 Sequence: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM Prediction: ---+-+-+----+++-+++----------------++++++++++++---+-+------- Confidence: 011434231232444344322102232211223214577776455751023231200000 Sequence: ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED Prediction: ----++--++-+++++-++-+++++++---+-------+---------------- Confidence: 0110552054333444376246756462223000000040000000000000000 *Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *Confidence: from level 0 (lowest) to level 9 (highest).

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RAID

The Detail Information for This Interaction