Detail

Detail-Interactions:
RAID ID:	RPI00001604
RNA/Protein Symbol 1:	TERC(htr)
RNA/Protein Category 1:	snoRNA
RNA/Protein Symbol 2:	CTNNB1
RNA/Protein Category 2:	Protein
Validated Method:	quantitative fluorescent reverse transcription polymerase chain reaction
Tissue:	bladder cancer cell line biu-93
PMID:	20556588
Detail description:	The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

Detail-Interactions:

RAID ID:

RPI00001604

RNA/Protein Symbol 1:

TERC(htr)

RNA/Protein Category 1:

snoRNA

RNA/Protein Symbol 2:

CTNNB1

RNA/Protein Category 2:

Protein

Validated Method:

quantitative fluorescent reverse transcription polymerase chain reaction

Tissue:

bladder cancer cell line biu-93

PMID:

20556588

Detail description:

The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

>sp|P35222|CTNB1_HUMAN Catenin beta-1 OS=Homo sapiens GN=CTNNB1 PE=1 SV=1 Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: -----------------++---+---------+---+++++++++++++++--------- Confidence: 682397888999966558563352322322745472754688568486946235548533 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: ----------++----------------++-++-+---------------++-------+ Confidence: 277398846554243476976955224269268585767676997763825425447255 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: +--+--------+-----------------+------+--------------------++ Confidence: 672746552267459994885477864762687359448858996988538886952656 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: ++-++----+-----+---++---+---++-+-+------------------++------ Confidence: 772682345633247577874333523356693534262242452677779844446267 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: -+---+---+-------------------+---+------+------++--+-------- Confidence: 947665396599849943954899665556557686348358986934527547793267 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -----+----++-----+---+------+++----------+--+-----++++------ Confidence: 939885422355857875343476848565533525644226746872525555276847 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: ---------------+------------++--++-------------------------- Confidence: 546366685823442568458865825744335624356788848938873875388268 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: ---------++++-+-------------+---++--+-----------+--+++------ Confidence: 658722723766725577849758467964679435535635898788524548323547 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: -----+--+-------------------------+------------+------+----- Confidence: 823777944895999287343254569293677956997648224265643565499298 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: -+-+++++++++++++--------+--------+-------+----+---+--------- Confidence: 967455858968876623357479597799898456828796574459765673286889 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: -----------+------------------------+---------+--+---------- Confidence: 699335952836966699768849468758847444654834763253254523885889 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: +----++++++++-+----++--+---------------------+--++++++++++-+ Confidence: 573456575786756437355467335454764878687856272532564465558435 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ++-+---------------------------------------------+---------- Confidence: 753442487888688988765342355358788778749599889832352227649848 Sequence: L Prediction: - Confidence: 9 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>sp|P35222|CTNB1_HUMAN Catenin beta-1 OS=Homo sapiens GN=CTNNB1 PE=1 SV=1 Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: ----------------------------------------+---+-+++----------- Confidence: 253285787988976564296586454734873284147332623165423759859999 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: -----------------------------+-++-+------------------------- Confidence: 589899988976899996899979787565757462667998978999979999888797 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: ------------------------------------------------------------ Confidence: 697389775588669995991377857983398389757835568756437659926861 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: ------------------------------------------------------------ Confidence: 365135756154279599978864535657523564683377126642798737456288 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: ------------------------------------------------------------ Confidence: 868842577698879957944997684775997798159368798943437577665324 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -----------------------------------------+------------------ Confidence: 913882373554999988566386857723644968857654772685566422577857 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: ------------------------------------------------------------ Confidence: 368589897923575488526616813843497568999799868968843567499568 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: ------------------------------------------------++---+------ Confidence: 648823733141245897867387247939872664266548655699436424646648 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: ------------------------------------------------------------ Confidence: 969997984784879577222223577275557812742574248787687897588599 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: --------++-------------------------------------------------- Confidence: 918324225424578776799999699888597667949994685618987794695678 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: ---++---------------------------------------+-+------------- Confidence: 566443785863557599688927567689999978588875583143636842665898 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: -----------------------+------------------------------------ Confidence: 689576423327395878631854432754798899887634244576557887361453 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ---------------------------------------------------++------- Confidence: 344236478487488999996334364447558347447489776832412446638945 Sequence: L Prediction: - Confidence: 8 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>P35222|CTNNB1 Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: -----------------------------+--+---+---++-+---------------- Confidence: 001100000000000000101010144435136413511355251021100000000000 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000001011000100001000000000000000001 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: ----------------------------------------+--+--------++-++--- Confidence: 131312010000040000001000000010010410122161160002434375275232 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: +------------------++---------++---+---+-------------------- Confidence: 632144011212311244265133122110553245444612232321110000200211 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: -----------------------------+------+--++------------------- Confidence: 042044030100031023011000111125000412731652042130021002131134 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -------+--++------+------+-----------+---+--++---+---------- Confidence: 342122462355102212621332163142341331464336315701252134211312 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: ----++-++----------+--++-++--------------------------------- Confidence: 310255155131041112363267488424201200102200431032122021102120 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: -++--+------+--------+--+-----------------+---+-++---+------ Confidence: 155347323243523022112711642142023211310032622352662125210021 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: ----------------------+----+---+--+------------------------- Confidence: 021002001103000210422453123722361063012321210001101002410230 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: -----------------------------------+-+----+----------+------ Confidence: 220200011311110001101101100101221135354224622211012205002110 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: -------------------+---+-----------------++-+--++--+++--+--- Confidence: 430320211022201432372235330110000031014115535426534656326423 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: +---------------+------------------------------------------- Confidence: 922122140012210151143412001000000000000000000000000000000000 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ------------------------------------------------------------ Confidence: 000000000000000000001000000000000000000000000000011220021014 Sequence: L Prediction: -- Confidence: 00 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: --+----------------------------+++---+---------------------- Confidence: 314100000000000021000100000000144333241330021232311000000000 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: -----------+-----------------+--+-+--+---------------------+ Confidence: 001000010333210000000010112335215051353010000000000010000133 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: -----------------------------------------------------------+ Confidence: 300310101000010010000001000000000000000000000000010011023234 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: +++++++------------+--++++-----+--+++-++--++---------------- Confidence: 564584530213300300060046453211152345404530643202000021020200 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: ---------------------------------+-+-+---------+------------ Confidence: 020003000100000000000000010001101403250220000023320000200110 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -----------------------------------------+------++++++------ Confidence: 000102102001000002122300000020120230010003102212454555100000 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: --------+--++-+++-++---+-++-----------------------+--------- Confidence: 000021024024437732641324045023102201011010000000004200200000 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: ---------++-++++-+--+---+-------+++-------------++---------- Confidence: 200001002652744313023220320020025442310010001000342012022010 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: --------+++-------------------+---+----+-+------------+--+-- Confidence: 032002236333200300222110000321420032102434210000000103800500 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: -+-+++++++++++------------------+--------+--+++-------+----- Confidence: 283456338855543201001210200200013202232104135361311222412200 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: ----+------+----+-----------------------------++---------+-- Confidence: 100241003025011230000000110000000000000000001074033002000400 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: ----++++++++++----+----------------------------------------- Confidence: 300247548674731120301000000000000000001000000000100001121012 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ---------------------------------------------+-------------- Confidence: 111301010302000000011221100010000000000000000312000000000001 Sequence: L Prediction: - Confidence: 0 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest).

The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.

The Predicated Binding Sites between TERC and CTNNB1
By miRanda	Structure	Match Score	Energy Score	TERC Location	CTNNB1 Location

The Predicated Binding Sites between TERC and CTNNB1
By RIsearch	Structure	TERC Location	CTNNB1 Location	Score

The Predicated Binding Sites of CTNNB1
RBPBD
RsiteDB
BindN	>sp\|P35222\|CTNB1_HUMAN Catenin beta-1 OS=Homo sapiens GN=CTNNB1 PE=1 SV=1 Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: -----------------++---+---------+---+++++++++++++++--------- Confidence: 682397888999966558563352322322745472754688568486946235548533 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: ----------++----------------++-++-+---------------++-------+ Confidence: 277398846554243476976955224269268585767676997763825425447255 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: +--+--------+-----------------+------+--------------------++ Confidence: 672746552267459994885477864762687359448858996988538886952656 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: ++-++----+-----+---++---+---++-+-+------------------++------ Confidence: 772682345633247577874333523356693534262242452677779844446267 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: -+---+---+-------------------+---+------+------++--+-------- Confidence: 947665396599849943954899665556557686348358986934527547793267 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -----+----++-----+---+------+++----------+--+-----++++------ Confidence: 939885422355857875343476848565533525644226746872525555276847 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: ---------------+------------++--++-------------------------- Confidence: 546366685823442568458865825744335624356788848938873875388268 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: ---------++++-+-------------+---++--+-----------+--+++------ Confidence: 658722723766725577849758467964679435535635898788524548323547 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: -----+--+-------------------------+------------+------+----- Confidence: 823777944895999287343254569293677956997648224265643565499298 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: -+-+++++++++++++--------+--------+-------+----+---+--------- Confidence: 967455858968876623357479597799898456828796574459765673286889 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: -----------+------------------------+---------+--+---------- Confidence: 699335952836966699768849468758847444654834763253254523885889 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: +----++++++++-+----++--+---------------------+--++++++++++-+ Confidence: 573456575786756437355467335454764878687856272532564465558435 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ++-+---------------------------------------------+---------- Confidence: 753442487888688988765342355358788778749599889832352227649848 Sequence: L Prediction: - Confidence: 9 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
BindN+	>sp\|P35222\|CTNB1_HUMAN Catenin beta-1 OS=Homo sapiens GN=CTNNB1 PE=1 SV=1 Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: ----------------------------------------+---+-+++----------- Confidence: 253285787988976564296586454734873284147332623165423759859999 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: -----------------------------+-++-+------------------------- Confidence: 589899988976899996899979787565757462667998978999979999888797 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: ------------------------------------------------------------ Confidence: 697389775588669995991377857983398389757835568756437659926861 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: ------------------------------------------------------------ Confidence: 365135756154279599978864535657523564683377126642798737456288 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: ------------------------------------------------------------ Confidence: 868842577698879957944997684775997798159368798943437577665324 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -----------------------------------------+------------------ Confidence: 913882373554999988566386857723644968857654772685566422577857 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: ------------------------------------------------------------ Confidence: 368589897923575488526616813843497568999799868968843567499568 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: ------------------------------------------------++---+------ Confidence: 648823733141245897867387247939872664266548655699436424646648 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: ------------------------------------------------------------ Confidence: 969997984784879577222223577275557812742574248787687897588599 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: --------++-------------------------------------------------- Confidence: 918324225424578776799999699888597667949994685618987794695678 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: ---++---------------------------------------+-+------------- Confidence: 566443785863557599688927567689999978588875583143636842665898 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: -----------------------+------------------------------------ Confidence: 689576423327395878631854432754798899887634244576557887361453 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ---------------------------------------------------++------- Confidence: 344236478487488999996334364447558347447489776832412446638945 Sequence: L Prediction: - Confidence: 8 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
RNAbindR	>P35222\|CTNNB1 Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: -----------------------------+--+---+---++-+---------------- Confidence: 001100000000000000101010144435136413511355251021100000000000 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000001011000100001000000000000000001 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: ----------------------------------------+--+--------++-++--- Confidence: 131312010000040000001000000010010410122161160002434375275232 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: +------------------++---------++---+---+-------------------- Confidence: 632144011212311244265133122110553245444612232321110000200211 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: -----------------------------+------+--++------------------- Confidence: 042044030100031023011000111125000412731652042130021002131134 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -------+--++------+------+-----------+---+--++---+---------- Confidence: 342122462355102212621332163142341331464336315701252134211312 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: ----++-++----------+--++-++--------------------------------- Confidence: 310255155131041112363267488424201200102200431032122021102120 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: -++--+------+--------+--+-----------------+---+-++---+------ Confidence: 155347323243523022112711642142023211310032622352662125210021 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: ----------------------+----+---+--+------------------------- Confidence: 021002001103000210422453123722361063012321210001101002410230 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: -----------------------------------+-+----+----------+------ Confidence: 220200011311110001101101100101221135354224622211012205002110 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: -------------------+---+-----------------++-+--++--+++--+--- Confidence: 430320211022201432372235330110000031014115535426534656326423 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: +---------------+------------------------------------------- Confidence: 922122140012210151143412001000000000000000000000000000000000 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ------------------------------------------------------------ Confidence: 000000000000000000001000000000000000000000000000011220021014 Sequence: L Prediction: -- Confidence: 00 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
Pprint	Sequence: MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS Prediction: --+----------------------------+++---+---------------------- Confidence: 314100000000000021000100000000144333241330021232311000000000 Sequence: QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT Prediction: -----------+-----------------+--+-+--+---------------------+ Confidence: 001000010333210000000010112335215051353010000000000010000133 Sequence: NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK Prediction: -----------------------------------------------------------+ Confidence: 300310101000010010000001000000000000000000000000010011023234 Sequence: KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL Prediction: +++++++------------+--++++-----+--+++-++--++---------------- Confidence: 564584530213300300060046453211152345404530643202000021020200 Sequence: VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC Prediction: ---------------------------------+-+-+---------+------------ Confidence: 020003000100000000000000010001101403250220000023320000200110 Sequence: LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA Prediction: -----------------------------------------+------++++++------ Confidence: 000102102001000002122300000020120230010003102212454555100000 Sequence: GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA Prediction: --------+--++-+++-++---+-++-----------------------+--------- Confidence: 000021024024437732641324045023102201011010000000004200200000 Sequence: AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM Prediction: ---------++-++++-+--+---+-------+++-------------++---------- Confidence: 200001002652744313023220320020025442310010001000342012022010 Sequence: AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL Prediction: --------+++-------------------+---+----+-+------------+--+-- Confidence: 032002236333200300222110000321420032102434210000000103800500 Sequence: VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV Prediction: -+-+++++++++++------------------+--------+--+++-------+----- Confidence: 283456338855543201001210200200013202232104135361311222412200 Sequence: QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF Prediction: ----+------+----+-----------------------------++---------+-- Confidence: 100241003025011230000000110000000000000000001074033002000400 Sequence: RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH Prediction: ----++++++++++----+----------------------------------------- Confidence: 300247548674731120301000000000000000001000000000100001121012 Sequence: SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD Prediction: ---------------------------------------------+-------------- Confidence: 111301010302000000011221100010000000000000000312000000000001 Sequence: L Prediction: - Confidence: 0 *Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *Confidence: from level 0 (lowest) to level 9 (highest).

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