Detail

Detail-Interactions:
RAID ID:	RPI00001603
RNA/Protein Symbol 1:	TERC(htr)
RNA/Protein Category 1:	snoRNA
RNA/Protein Symbol 2:	CD44
RNA/Protein Category 2:	Protein
Validated Method:	quantitative fluorescent reverse transcription polymerase chain reaction
Tissue:	bladder cancer cell line biu-92
PMID:	20556588
Detail description:	The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

Detail-Interactions:

RAID ID:

RPI00001603

RNA/Protein Symbol 1:

TERC(htr)

RNA/Protein Category 1:

snoRNA

RNA/Protein Symbol 2:

CD44

RNA/Protein Category 2:

Protein

Validated Method:

quantitative fluorescent reverse transcription polymerase chain reaction

Tissue:

bladder cancer cell line biu-92

PMID:

20556588

Detail description:

The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

>sp|P16070|CD44_HUMAN CD44 antigen OS=Homo sapiens GN=CD44 PE=1 SV=3 Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: ----------------------------+--------+--+++-++-------+---++- Confidence: 984987899699899793773977482858978747372297825734734975863446 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: -------+-------+-+-----------+-----------+--+---++++++-+---- Confidence: 423748558726454466276979798756723336546335466652586775252662 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: -------------------------+---++++++-+++++++--------+------++ Confidence: 625443445437368659777482846827547864796778523327243452233355 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: ++++++++++--+------------------------+---++--+++-+-++++++++- Confidence: 699989888722576467448455578537473433573255544667362778678862 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: +------------++++-+++++++++++++-+---------+--+-++-+--------- Confidence: 438898899953256552454456547788545433422452434555566423256679 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: ------+-+++-+----++-++-----++++---------+-+-++--+++++-++---- Confidence: 898823546752722224625622224546522556674252737652744773753234 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: --------------------++++-+++++++++++-+-+--+-----++-+++++++++ Confidence: 348456884676666642325667365776775677262542444323552686668578 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ++++-+---+-+++++++-+++++++++--------------+-++++++-++-++++-+ Confidence: 676728232735566467296868755423357767932334948854872442545545 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ---+-+-++-------+----+-++++++++++++--------+--++++++++++++++ Confidence: 622625245678568772322536577898874552244436555255868588758755 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: +++++++++++-+++----+-++++++++++-----++-++-+------+-+-++++-++ Confidence: 876998877662644442552677476756822535572972825426853525787278 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: +-+-+--+---++++++++-++++-++++++-++-++++++-++---------------- Confidence: 535253455325557877725676265746626726789783952386899999939989 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------+++++++++++---+--+-+---++-++-+++-++----------+++-- Confidence: 999999875446899978656345424535333563653757278224794874254622 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ----------+----------- Confidence: 3537836542726228573978 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>sp|P16070|CD44_HUMAN CD44 antigen OS=Homo sapiens GN=CD44 PE=1 SV=3 Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: -++---+------------------------------+--+++----------------- Confidence: 444321456486898784998989997927633423461265551354679977978725 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: -----------------+-----------+++-+++-+-++++-+--+-+--+------- Confidence: 433635239857576344352645173315452433151655426125252342452432 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: ------------------------------------------------------------ Confidence: 758597776766267658999999968976676279478734587859887788887622 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: ------------------------------------------------------------ Confidence: 232553524358699899779799878777677879949998897986989788888357 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: -----------------------------------------------+------------ Confidence: 667779798987558799967687798856997752876899997533551515689789 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: ------------------------------------------------------------ Confidence: 778978576454274332422565866984668977997433234586352354689657 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: ----------------------------------------------------+------- Confidence: 667555542334599897657474948722336666785496488641343434536786 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ------------++++--------------------------+----------------- Confidence: 666773677264334321724655886857888987734321531356134544142574 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ---+-------------------------------------------------------- Confidence: 964323413798999866657483664364558757588887956554536677433465 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: ---++-+--------------------+--+----------------------------- Confidence: 333632314344777897974622521432368757534247579989969642242844 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: -----------+-------------+-+---------++++-++++-------------- Confidence: 585676612333211232366742542622352474446661763433649699837888 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------+++++++++++---+++++----++-+--+-+-++--------+---+-- Confidence: 999979563255899878755334534431422652513714275213563744122542 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ----------++-++---+--- Confidence: 5245736361745557564624 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>P16070|CD44 Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: --+---+----------------------------+-++++++-++-+------------ Confidence: 247123501400000100000000102012031445466688827545010000001040 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: ++----------------------+--+-++++++++-++++---++++++++------- Confidence: 562120110130113121233123822546685888849875443578687573314013 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: ----------------------------------------+----+-------------- Confidence: 000000000000000000000000100200000000010251222511111300020000 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------+++++++++++-+-++++-----------+-------------------- Confidence: 001001124487999788685353756533131230423544232130003001100100 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ------------------+---- Confidence: 00000000002003200061230 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: --+--++---------------------+-+++---++++++++++-------------- Confidence: 115225520100000100000001200033645113465687644412000001013011 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: ----------++-+---+-----------+-+-+-------------------------- Confidence: 010000010336151204220010201135152300000022310001112220011101 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: ----------------------------+++-+++-++++++------------------ Confidence: 000010000000000020000000010138735653583665121111000010000011 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: -++--+-------------------------------------------------++--- Confidence: 343325302111110000000110000000000000010100101111222233344111 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: -----------+--+-------------+++++++-------------++---------- Confidence: 000210101115204110100011122354545443123122000203343333010000 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: --------+---+--++------++++++++++------------+--++++--+----- Confidence: 000010003010403561222206458466544120000000211413555413402000 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: --------------------------------------------+++---+++++++-+- Confidence: 010210100000000100120200000002120000000100203441105755533241 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ---------+-+++++-+++------------------+-++++++++++++++++-+-- Confidence: 201122222434346435752211000000000000004257646656786555433422 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ----------------+----+-+-------++--+--------------------+-++ Confidence: 012321211000000140312334101032344123100000000000100001335344 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: +++++++++-------------------------------+--------------++--- Confidence: 555794476101000000010021011000010000111231020000020233244122 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: ---+-+++-+++-+++++---+-++++++++++++++++++-++---------------- Confidence: 222413552554354434212434464646566645445453453221103000000000 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------++++++++++++-+++++++---+---++++++-+-++------------ Confidence: 000000120265998876899534666445220533266657315034222121210200 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ----------++-++---+--- Confidence: 1000000001651451225111 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest).

The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.

The Predicated Binding Sites between TERC and CD44
By miRanda	Structure	Match Score	Energy Score	TERC Location	CD44 Location

The Predicated Binding Sites between TERC and CD44
By RIsearch	Structure	TERC Location	CD44 Location	Score

The Predicated Binding Sites of CD44
RBPBD
RsiteDB
BindN	>sp\|P16070\|CD44_HUMAN CD44 antigen OS=Homo sapiens GN=CD44 PE=1 SV=3 Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: ----------------------------+--------+--+++-++-------+---++- Confidence: 984987899699899793773977482858978747372297825734734975863446 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: -------+-------+-+-----------+-----------+--+---++++++-+---- Confidence: 423748558726454466276979798756723336546335466652586775252662 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: -------------------------+---++++++-+++++++--------+------++ Confidence: 625443445437368659777482846827547864796778523327243452233355 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: ++++++++++--+------------------------+---++--+++-+-++++++++- Confidence: 699989888722576467448455578537473433573255544667362778678862 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: +------------++++-+++++++++++++-+---------+--+-++-+--------- Confidence: 438898899953256552454456547788545433422452434555566423256679 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: ------+-+++-+----++-++-----++++---------+-+-++--+++++-++---- Confidence: 898823546752722224625622224546522556674252737652744773753234 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: --------------------++++-+++++++++++-+-+--+-----++-+++++++++ Confidence: 348456884676666642325667365776775677262542444323552686668578 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ++++-+---+-+++++++-+++++++++--------------+-++++++-++-++++-+ Confidence: 676728232735566467296868755423357767932334948854872442545545 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ---+-+-++-------+----+-++++++++++++--------+--++++++++++++++ Confidence: 622625245678568772322536577898874552244436555255868588758755 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: +++++++++++-+++----+-++++++++++-----++-++-+------+-+-++++-++ Confidence: 876998877662644442552677476756822535572972825426853525787278 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: +-+-+--+---++++++++-++++-++++++-++-++++++-++---------------- Confidence: 535253455325557877725676265746626726789783952386899999939989 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------+++++++++++---+--+-+---++-++-+++-++----------+++-- Confidence: 999999875446899978656345424535333563653757278224794874254622 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ----------+----------- Confidence: 3537836542726228573978 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
BindN+	>sp\|P16070\|CD44_HUMAN CD44 antigen OS=Homo sapiens GN=CD44 PE=1 SV=3 Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: -++---+------------------------------+--+++----------------- Confidence: 444321456486898784998989997927633423461265551354679977978725 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: -----------------+-----------+++-+++-+-++++-+--+-+--+------- Confidence: 433635239857576344352645173315452433151655426125252342452432 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: ------------------------------------------------------------ Confidence: 758597776766267658999999968976676279478734587859887788887622 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: ------------------------------------------------------------ Confidence: 232553524358699899779799878777677879949998897986989788888357 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: -----------------------------------------------+------------ Confidence: 667779798987558799967687798856997752876899997533551515689789 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: ------------------------------------------------------------ Confidence: 778978576454274332422565866984668977997433234586352354689657 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: ----------------------------------------------------+------- Confidence: 667555542334599897657474948722336666785496488641343434536786 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ------------++++--------------------------+----------------- Confidence: 666773677264334321724655886857888987734321531356134544142574 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ---+-------------------------------------------------------- Confidence: 964323413798999866657483664364558757588887956554536677433465 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: ---++-+--------------------+--+----------------------------- Confidence: 333632314344777897974622521432368757534247579989969642242844 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: -----------+-------------+-+---------++++-++++-------------- Confidence: 585676612333211232366742542622352474446661763433649699837888 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------+++++++++++---+++++----++-+--+-+-++--------+---+-- Confidence: 999979563255899878755334534431422652513714275213563744122542 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ----------++-++---+--- Confidence: 5245736361745557564624 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
RNAbindR	>P16070\|CD44 Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: --+---+----------------------------+-++++++-++-+------------ Confidence: 247123501400000100000000102012031445466688827545010000001040 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: ++----------------------+--+-++++++++-++++---++++++++------- Confidence: 562120110130113121233123822546685888849875443578687573314013 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: ----------------------------------------+----+-------------- Confidence: 000000000000000000000000100200000000010251222511111300020000 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------+++++++++++-+-++++-----------+-------------------- Confidence: 001001124487999788685353756533131230423544232130003001100100 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ------------------+---- Confidence: 00000000002003200061230 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
Pprint	Sequence: MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL Prediction: --+--++---------------------+-+++---++++++++++-------------- Confidence: 115225520100000100000001200033645113465687644412000001013011 Sequence: PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN Prediction: ----------++-+---+-----------+-+-+-------------------------- Confidence: 010000010336151204220010201135152300000022310001112220011101 Sequence: ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS Prediction: ----------------------------+++-+++-++++++------------------ Confidence: 000010000000000020000000010138735653583665121111000010000011 Sequence: GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE Prediction: -++--+-------------------------------------------------++--- Confidence: 343325302111110000000110000000000000010100101111222233344111 Sequence: TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD Prediction: -----------+--+-------------+++++++-------------++---------- Confidence: 000210101115204110100011122354545443123122000203343333010000 Sequence: EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN Prediction: --------+---+--++------++++++++++------------+--++++--+----- Confidence: 000010003010403561222206458466544120000000211413555413402000 Sequence: PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS Prediction: --------------------------------------------+++---+++++++-+- Confidence: 010210100000000100120200000002120000000100203441105755533241 Sequence: HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT Prediction: ---------+-+++++-+++------------------+-++++++++++++++++-+-- Confidence: 201122222434346435752211000000000000004257646656786555433422 Sequence: LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV Prediction: ----------------+----+-+-------++--+--------------------+-++ Confidence: 012321211000000140312334101032344123100000000000100001335344 Sequence: TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR Prediction: +++++++++-------------------------------+--------------++--- Confidence: 555794476101000000010021011000010000111231020000020233244122 Sequence: SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL Prediction: ---+-+++-+++-+++++---+-++++++++++++++++++-++---------------- Confidence: 222413552554354434212434464646566645445453453221103000000000 Sequence: ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET Prediction: ----------++++++++++++-+++++++---+---++++++-+-++------------ Confidence: 000000120265998876899534666445220533266657315034222121210200 Sequence: PDQFMTADETRNLQNVDMKIGV Prediction: ----------++-++---+--- Confidence: 1000000001651451225111 *Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *Confidence: from level 0 (lowest) to level 9 (highest).

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