Detail

Detail-Interactions:
RAID ID:	RPI00001598
RNA/Protein Symbol 1:	TERC(htr)
RNA/Protein Category 1:	snoRNA
RNA/Protein Symbol 2:	ATM
RNA/Protein Category 2:	Protein
Validated Method:	quantitative fluorescent reverse transcription polymerase chain reaction
Tissue:	bladder cancer cell line biu-87
PMID:	20556588
Detail description:	The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

Detail-Interactions:

RAID ID:

RPI00001598

RNA/Protein Symbol 1:

TERC(htr)

RNA/Protein Category 1:

snoRNA

RNA/Protein Symbol 2:

ATM

RNA/Protein Category 2:

Protein

Validated Method:

quantitative fluorescent reverse transcription polymerase chain reaction

Tissue:

bladder cancer cell line biu-87

PMID:

20556588

Detail description:

The effects of combined RNA interference (RNAi) of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) genes on telomerase activity in a bladder cancer cell line (BIU-87 cells) were investigated by using gene chip technology in vitro with an attempt to evaluate the role of RNAi in the gene therapy of bladder transitional cell cancer (BTCC). HTR-siRNA and hTERT-siRNA, especially their combination, siRNA hTR+hTERT, specifically and effectively suppressed the expression of both hTR and hTERT mRNA and telomerase activity. Gene chip analysis revealed that 21 genes were down-regulated (ATM, BAX, BCL2, BCL2L1, BIRC5, CD44, CTNNB1, E2F1, JUN, MCAM, MTA1, MYC, NFKB1, NFKBIA, NME4, PNN, PNN, SERPINE1, THBS1, TNFRSF1A, and UCC1).

>sp|Q13315|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=3 Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: ------------+-----+-+++++--++-++--+-----+---+++++++-++------ Confidence: 949998999989536434737576622558576854443652547555798286645899 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: ---------------+--+-+-+-+++++++++-+------+---+--++++++-+---- Confidence: 938852263242355765635362879789777252823795489633589589367459 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: --------+--++---+---------------+-------------------+------- Confidence: 987978375425534654657329893887287234538446648899393958272422 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: ---+----------++---++++--+-----------+--+++++++------------- Confidence: 473688992983884732355442352377499427662284797863634989992879 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: -------+-+---------------------+--------------------++++++++ Confidence: 337762749597699999977993944452653482699999969593954484597768 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: +-+++++-++-----------------+++++++--++---------------------- Confidence: 525585648577369699999992242797898735646783879989999996697564 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: ++--+-++++++++++++-++-+-++++------------++------------------ Confidence: 472553555777888765346262898543795899383556324578999896892367 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: -+---+--------------------+++++--+--+----------+++++++++++-- Confidence: 252455652758369889954763228756822565599379965247878577555625 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: -+----------+--+++--+-------------------+--------+--+-+----- Confidence: 459654954948536454255874787978894746539748843882364382544777 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: --------+------+-----------++------------------------------- Confidence: 892777324672427535865666492754262348947999689884762345844995 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: ---------------+-+--+---------------++---------------------- Confidence: 448649999598927465356666598569755222454243746689989895437728 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: --------------+++--------------+--------------++-++--+--+--+ Confidence: 888599276663234565432732362448759777856567363255465324375727 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: --------------------+--------++------------++++----+--+-+--- Confidence: 888788773839999977465232542285554256654625354652234755476466 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: ----+--++++++++++--+----+----+-------------+--++---+-+------ Confidence: 387256667559874785554889488224983999998237764845253845522446 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: -+------------------------+-------++++---------------------- Confidence: 453737658765324366584542255253322256555558357977472378898999 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: --------++-++++-+-+----++--------++-++++-------------------- Confidence: 949989995736778355643276638967963463645726276969999479576735 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+-+++-----+--------------+++-++++++--+----- Confidence: 979999999937822735365552255448947997992363556356565733655693 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: -----------+++----+-----------------+----------------------- Confidence: 998986563256653529579894892389554323438894958268694697469987 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: -----+--------+----++-++++--+----+--+--------+-+---+-------- Confidence: 653386776743836563458267786465746682427752727574253535222632 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: -----------+-------------------------++-+---------+--------+ Confidence: 553864625224666499899927237763688588755563256555694388538355 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: --+++-----------------------------------------------+------- Confidence: 244558748795598399998969452333623877999653584583245258999589 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: -+----------+--------------------------+---+-+++-+-+-+------ Confidence: 855374282366437478535883489839996997488432273555462727222834 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: -----------------------------------++++++------------------- Confidence: 572452456359959896698699999994975345586762257678676842542322 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: --+---+-------+--+++-+-------+++-++--------------++-++--+--- Confidence: 544478584693824527785728858826562643289899984663267276227583 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: -------------++---------------------------------+----------- Confidence: 976999399925755444383779938994599626342426785838526387789934 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: ------------------------------------------------------------ Confidence: 982257228268878797999959958959686942698799359984424342829495 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: --------------+-++-+-++++------------------------+----+--++- Confidence: 997899979986795854274865933439999987892849488847276463645763 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: ------------+-++-------------------+------------------------ Confidence: 525339689898754432236586929996993945657222442688699726854974 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: -----------+-+++++--+--------------------------+-++--------- Confidence: 966427563326246756664688958956899995495459957685876455269247 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: --+++----------------------++++++-----+--+------------------ Confidence: 564762235679437336468939434967865342837445456789999969596857 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: ---------------++-++----------------------------------+---+- Confidence: 766839448356793543774478599286558225473499559999999762542262 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: --+-----------+--+++++++++++--+------+----++++++--------++++ Confidence: 654239358723586234577988655732533447958674777695586796237889 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: +++++-----------------+--------------------++--+++-++------- Confidence: 998742774999698973859848722567583899396826356224652563653333 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: --+++-++++++++-++------------+------+-+-----+--+---+-+++---- Confidence: 226673575567663654839579999954367254565433436444352848446447 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: ----------------+++++--------------------+---+-------------- Confidence: 849279823796254268684356748956978759829295453543385788987964 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: ----+-----------++-+-+++++------++-+-+---------++-+--------- Confidence: 366363654636325254452545442833654557653633633265666826956772 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: +---+---------+---------------++--++----------+------------- Confidence: 535356327232536848675973875862655255472393924553224727558487 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ------+-------------+-++------------------++-+-++----------- Confidence: 898889539997999956425247358259843798794875754624565429863723 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: -++-+----------------+---+------+--------+---++-+-+-------+- Confidence: 255563473466988959627526276743894469229554343652648522246768 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: --------------------------------+-++---++-+-+------+-+-+++++ Confidence: 685698567876898884339629967543224256233954847667369556255557 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: -----+-++--------++--------+--+-++++++++--+---------+--+--++ Confidence: 632266255322235347742455668572636659664773579799698856372284 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: +---+--------------------------------+------++---+--+------- Confidence: 745357975595788266868979939838397346742824355624284243388699 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: -----+--++----------------+-----------------+-++--------+-++ Confidence: 558867437556448886899678836845545564999999856447523723424387 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: ++-+++-++++++-++-++----+---+-++++++--+-----------------+++++ Confidence: 593797358646636446433425964539698682674867689959989495556587 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: +++--+--------+--------------+--------+--+-+--+---+--------- Confidence: 786246437634525724988999636575872244234664752455374875472852 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: ------+++++++++-+-++--+-----------------+++++++++-+--------- Confidence: 996776776857855274744474778767996995245377888988827364438735 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: --+-----------------------++++++++-------++---+--++--------- Confidence: 326267566926385896899687424678685536364254525446255223535997 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: ----------------------------+--+-++--+++----------+--------- Confidence: 999978945982699987999999798354472862365568639956765382399968 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: -----------------+------+---+--+---------------++---------+- Confidence: 448479599989786474662364653446359987786727834775545424555473 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: -------------------------+--+-+-+---------------+--++------- Confidence: 344289599799969999997856856656526344335835383633423653623854 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: ---+---+---+--------------+----------------+-++--------- Confidence: 37466865876583437256475276565439478966887425657754653839 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>sp|Q13315|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=3 Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: ------------+---+-+++-+++---+-++--+-----+---+-+-+++-++--+--- Confidence: 617896997756513444838186432254364855521351357152666257423467 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: -+----+--------+--+-+-+-+-+-+++++------------++++++-++-+---- Confidence: 745611365146536633425443515158364334723781567744699268155236 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: --------+-+-+---------+---------++++----------------+-+-+-+- Confidence: 866957384441426634625347893664157333315235438898393738476252 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: --+-----+--+---+---+-----+-----------+--+--+++-------------- Confidence: 283275775755243421351222633465367235631262145532434857996959 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: -----+-+-+-------------------+-+---------------+--+-+++++--- Confidence: 324347546652247689967772722324642181699998759484613176584211 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: +-+++-+-++--+----------++-+++++++++-++---------------------- Confidence: 344351345477329567975583525778688854554252638889997964484574 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: -+------------+-----+-++++++-+------+---++------------------ Confidence: 241715121112234423533354777414443678371543113767885482794657 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: -+-----------------------++++++--+--+--------+-++++-++---+-- Confidence: 142432651557369869975563158633811466565378765535556235121337 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: -+----------+---+-----------------------+--++----+--+++----- Confidence: 458324822525624142353962568877794644446754533671264344433636 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: --------------------------+++-+-+--------------------------- Confidence: 583768485773657244884364344561465527745787858978973468843552 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: ++--+------------++-+-------------+--------------------+---- Confidence: 364545799398916286425323155338362351322254644688989796445526 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: ------------+---+---+-+---+-----------------------------+--+ Confidence: 777399276563412174235631184329738863657478645554924431674326 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: --------+-+------------+--+--+----------+----+++---+--+-++-- Confidence: 676777544437588857242233335363264237363436321453263442555556 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: -------+---++++++--+----+----+------------------------------ Confidence: 288436843336753643341577466325772698487136514911234132432445 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: ------------------------------------------------------------ Confidence: 572546557766114367574462263464542531456347465877253268798968 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: --------------+-+-+--+-++--------------+--+---------------+- Confidence: 847969691442114253732465627768965638363525461948689278524442 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+--++--+--------------------------+--+----- Confidence: 767558989827815634314643377146732872873153243634321764435694 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: ---------+-++---+-+----+-------------+---------------------- Confidence: 852742141444443348566783383698787412337784748265575567798875 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: -----+----------------------+----+-------+------------------ Confidence: 231274334453711671751443418543566572225763735273676475436442 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: --------------------------------------+--------------------- Confidence: 556735535444888688899858527674279488624434126432672577738682 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: ---++-------------------------------------------+----------- Confidence: 324545466998498587984849786875987797999686476556343326689688 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: -------------------------------------------+---------------- Confidence: 824253485287469268748987667659792898698467546333776699865946 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: ----------------------------------------------------------+- Confidence: 594866987177748764695699998998968795789889898898575983635441 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: ----------------------------------------------------+--++--- Confidence: 743687366787963975355589999974432114197788995889632251175763 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: ------------------------------------------------------------ Confidence: 794988655956864755575475853655567449666668978968799789888977 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: ------------------------------------------------------------ Confidence: 887577367789999897889769999989798856988899689696314353858897 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: --------------+--------------------------------------------- Confidence: 999898877885884843358336148579887996994849488699748576478475 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: ------------------------------------------------------------ Confidence: 873436487999498799898999959955872853755233312486597666724733 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: ------------------------------------------------------------ Confidence: 515115562252542442896899958967989998499897968875978999699467 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: ------+-----------------------+----------------------------- Confidence: 771313524224516677999979678323411452822852877774553436164735 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: ---------------------------+-------------------------------- Confidence: 538638459798995667326378279324754655675598789889999999698749 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: ------------------------------------------------------------ Confidence: 989989899988998998877264447487678969979899647725885998282223 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: +----------------------------------------------------------- Confidence: 612242687689785956438618833347381578596758956564548626886987 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: ------------------------------------------------------------ Confidence: 767668778877659979989989948978797995586695351242595698857355 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: -------------------------+---------------------+------------ Confidence: 749679979998897854334657955735689879969595875334453789999975 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: ------------------------------------------------------------ Confidence: 376335633578877648835544365951982361667677999996794999987864 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: ------------------------------------------------------------ Confidence: 677567268256831917889988988986577476875674435525775758775797 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ---------------------------------------------+-------------- Confidence: 688577127753664433456934689489888558387285233333246429866944 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: ------------------------------------------------------------ Confidence: 734737764755877928636346238763997898679976785254671773848869 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: ------------------------------------------------------------ Confidence: 768478887777788896747839878667646564555355376858779475845844 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: ------------------------------------------------------------ Confidence: 998494745978989995375789676262154532436175398899999979938626 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: ------------------------------------------------------------ Confidence: 469579987697999887767669939849698799978947793478359352539858 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: ------------------------------------------------------------ Confidence: 426852772589969894799558975985526338757984583233535834335522 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: -------------------------------+-----+-----------------+-+++ Confidence: 315436973685387577368887998893342426444967898768475474341354 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: -----------------------------------------------------+++++++ Confidence: 112554879889975834987889546572751543354571722375283843658435 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: ----+-+--+--+---+-----+-----------------------++--+---+----- Confidence: 261834323552343753112262754886995993354224252244145233411543 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: -++-------------------------++++---------------------------- Confidence: 443435643943545736687355446334344234362294267598354268515786 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: -------------------------------+-++---------------++--+----- Confidence: 698978954761488677898899488616335441334647636416127722595987 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: ------------------------+---+--+--------------------------+- Confidence: 444437284536872461331331322352354777885863461783445547416642 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: -------------------------+---------------------------------- Confidence: 254799789499959647773546747314234488775667777998646235626896 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: ---------------+-+-------------------------------------- Confidence: 78468931853172164426577587388539899958966821532435424818 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>Q13315|ATM Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: -+----------+--++++++++++----------------------------+--+--- Confidence: 252001102001541777959786822421201011010000101121031045215431 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: --------------------+--++-+-+--++--+---------+++++++++++---- Confidence: 031011100300120322126445845364367045114102421675587695762341 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: --------------------------+-------+------------------------- Confidence: 011001001000001120044040008202303253240323331100000011012203 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: --------+-------+------------------------------------------- Confidence: 201431125011001352212221132100000000000000014031032001001010 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: -----------------------------------------------+-+---------- Confidence: 120113141202401010000000000012124201200010020105153232000000 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: --------+----+----------+--++++++--------------------------- Confidence: 011021325321460101002004543787765412340210221040000000100000 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: ---------------------+++++++-+------------+----------------- Confidence: 000000010000212011023578788845342200002003512012011000000000 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: ---------------------------+-++-+++-++---------------------- Confidence: 110110020000000000000000124725736853861200002001100000000000 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: ------------------------------------------------------------ Confidence: 011113001000211203100001211023101210010030001000010011233211 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: ------------------------------------------------------------ Confidence: 000100000000010100000000002212412441014110000000000000010001 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: -------------+---------------------------------------------- Confidence: 001010000300052214413101220100000000000000000000000001000000 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: ----------------+---------------------------------------+--- Confidence: 000000000000000152113000100000010000000000000001011032016204 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: ------------------------------------------------------+----- Confidence: 211421242122200111001123123201400120012131012001000401523000 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: ------------------------------------------------------------ Confidence: 000010002012121111011001300122001000000000010022000000000000 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000001420000001001100010 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: ------------------------------------------------------------ Confidence: 010000000000110111300000010000000000000100001000000100010020 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+------------------------------------------ Confidence: 000000000010010006232312000000012001001000000000000000000000 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: -----------++++++-++---+------------------------------------ Confidence: 100300111245668892754126100000100120000000000010000001020013 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: ----------+------------------------------------------------- Confidence: 132302131152023001000000000000000100100000000000000000010000 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: ------------------------------+---------------+------------- Confidence: 000000011111100200120021331112601320010000111054002100020024 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: ------------------------------------------------------------ Confidence: 233420000000000000000000000000000000100000000000210010001311 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: ------------------------+----------------------------------- Confidence: 021400000100000000010000530141003000000000000010000000000000 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000021234 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: ------------------------------------------------------+++-++ Confidence: 112100000000000010211000000000111000000010002001112343779466 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: +-------------------------+--------------------------------- Confidence: 613221130000000001101120025004101200010000000000000000010000 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000012000100000000110000000000 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000121120000000000000100100010200011000 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: -----------------------------+--+--+----------------------+- Confidence: 000000000000000000001000240035126025412333143302100030111054 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: ------------------------------------------------------------ Confidence: 121111001000000000000000000000000001000101011101000000100210 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: ------------------------------------------------------------ Confidence: 101220110110100000100000221442133001000000000000000000000000 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: ------------------------+--++------------------------------- Confidence: 011240240011001111323402611561021013104400440001000100110021 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: ------------------------------------------+---+---+-----+++- Confidence: 001200000000000000000000000000000000000002543284205113315853 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: +++-+----------------------++--+++-------------------------- Confidence: 855352323323332033121134123552356622111010010000000000000000 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000010201013000211201000000100101300 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: ------------------------------------------------------------ Confidence: 421010000000000000000010042121111100000000000010010010000010 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: +---++-+------------------+--+--++-+-+---------------------- Confidence: 512475261100000000011122325148146527254212000000100000011001 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: --++--++------+-+------------------------------------------- Confidence: 225742770332118353341000000000000100101000021101011023122203 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ----++-++--+----+----------------------+--+--++-+---+------- Confidence: 433385465015011250011000100010001011222611642554510170001000 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: -----------------------------+------------------------------ Confidence: 000000000001001031232323333326201100000000000000002002130302 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: ---------------------------------------------------+-------- Confidence: 103110123202010001200020000113110310001230203042411511011011 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: ------------------------------------+--+-+------------------ Confidence: 011201021131011001210010000001111234524525410000000000000011 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: ------------------------------+----------------------------- Confidence: 110131133204012100100010030211523320100000001000221214200200 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: -----+---------------------------+-------+--------------+--- Confidence: 240027014110012314400130003001132740133015134222211211145142 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: -+--------------------------------------------------------++ Confidence: 151123011011112113200001000101231231031014001110210022142465 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: -++-+-------------------+------------+---++-+---+----+++++++ Confidence: 467454342311022013001110522211143444274246536102514439898987 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: +-+-+-+++++++---+-++++++-----------------+++++++++++++++-++- Confidence: 635383897968734484767687432122011003312336756877969899874863 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: ++---------+---------------+++++-++++-+--------------------- Confidence: 753240024025314012100124421575782665746302211100110211241201 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: -----+-+---+-----+------+---+++++++++-++--+------+++-++----- Confidence: 110035454315201015412213533386765986648831542144488716524021 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: ------+---+--------------+++++++-----------++++++----------- Confidence: 212102612273143112221134455986573111211032256658744111141132 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: ------------------------------------------------------------ Confidence: 211101410421033241323011130121111000000000000000000000001001 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: -------++--+--++----------+++-+----+---++--+--+++++++++-- Confidence: 213243265029435933421143237563724235431851494476758988940 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: -----------------++-+-+++---+--+---------+--++-++++--+-+---- Confidence: 133001000000101213724356632042232020221024126334555114142200 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: ---------------+------+++-+-++-++------------+-+++++-+-+---- Confidence: 010102000101100513323244334235244223220002100424999736241210 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: ---------------------------------+------------------------+- Confidence: 000001201112200231001030000000022522000000000000000000003232 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: +-------++++--++++++--------------------+--++++++----------- Confidence: 300310027443114644343322001100100030120253354454513100000000 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: ----++++--------------------++--+-----------------++++++++-- Confidence: 100156442301300000000000000044123100000000000001027554743412 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: +----------------------++-+-++++++++++---------------------- Confidence: 313110100000000000000113323365776865673300000000000000000000 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: ------+--+-+--------+-++-+++-+-----------+------------------ Confidence: 321020433433011000215254254304100000000034020010000000000000 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: -----------------------+++++-+---+-------------+++++++------ Confidence: 021132000000000000002003545623331323333200002135644543323110 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: -+----------++------------------------------------+--+++---- Confidence: 050010000233443231332001210000000000010010000012334233340000 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: ---------------------------+--+++--------------------------- Confidence: 000000000101110313012012302512435100000000000010000000000000 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: +---+------------+------++-----+--+------------------------- Confidence: 401040000000012024203012431001041051000010000000000000000000 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: --------------+-+-+++------+-------------------------------+ Confidence: 000000100010334253456222111400010000000000001002002000001005 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: --------------------------------------------++-++-++--+-++-+ Confidence: 010130022230000000000201100002000202000022025625435531415824 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: ----+---++-++-----------+----------------------+-----------+ Confidence: 311142005306721020111210400021101100000300000036010301021104 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: -------------------------------+---+++---------------------- Confidence: 211000020000010000010000000000041114432110000000000000000000 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: --------------+---+--+-------------------------------------- Confidence: 010001001102123323500411210000000000000000022000000000000000 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+-+++-++---+------+---++++++++-++-+-------- Confidence: 000000000000000014247624410240000005103553555552543310110012 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: ---+-----+-+-----------+------------------------------------ Confidence: 011412010523202021100014000000000000000000000000010001000002 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: --+-----------+---+-+-+-++--+--------------+---------------- Confidence: 315102300001104003434362583253011300000002041201012111111000 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: ----------------------------------------+--++--+------------ Confidence: 000000000110000000000010020000000000123342274034202200000002 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: ---+-------+---------------------------------+-++----------- Confidence: 102530000004000000000010000000000000000001002505411020000000 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: --------+------------------------------+---+--++-+---------- Confidence: 010000103301200000000000000010000000200402362343233321021100 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: -----++--+-----------------------------------------------+-- Confidence: 003123300400000000200000000000011000130000100000000001000322 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: --------------+--------------+-------------------+-+-------- Confidence: 000000000000023313010110000004012222000001000010143422212001 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: ----------------+++------------------++-----+--------------- Confidence: 002000000010012253410100000001000320055330005100000011010000 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: -----------------------------------------------+++++---+---- Confidence: 001000020031000001000000020000000002000000000004554322240001 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: -----------+--+-------++--++-------------------------+------ Confidence: 000200010005105011320043314300000000000000000000000034322322 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: ------------+++--++-+------------------+-------------------- Confidence: 000000000203543325524210010101002001213533110001003000000003 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: -------------------------------------------------+---------- Confidence: 020300000012200211000000000000000001200010000000031202110000 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: ------------------------+----+------------------------------ Confidence: 001100220010000000000000303005332102000010000001000020100202 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: --+------------------------+-----------------------------+-- Confidence: 214010100000012222211001200401000020031100000000000000122333 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: -----------+--+------+++--+-------++------++-------------+-- Confidence: 100000000024223201102635323301000134120212440030000000000310 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: ----++--------------------------------------+--------------- Confidence: 322243100000000010000010030311000000200021124222111122000011 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: ----------------------------+--------------+---------------- Confidence: 000120000000000001000000010040020001000102032130000000000000 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: -------+--------++++-----+---------------------------------- Confidence: 020001030000003243852133060100200000000000000000101001000000 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: ------------------------------------------------+-+--------- Confidence: 010011020000000000000001110000000101001000000202403310000000 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: ------++--------------------------+-+-+--+++-+++-++--+------ Confidence: 000022640010000000000000000000322243334224463466344233121001 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ----------------+----------------------+--++++++++++++------ Confidence: 011001120000000032012112231000010221200603897994595475301002 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: ----------------------+--+---+-----------++++++-----++-----+ Confidence: 010002111322000000001232052024100000011116864550111053112124 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: +--+--+---------------+------+---++------------------------- Confidence: 403300410000000000001032011013222441220001100000000200000031 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: ----------------------+--++++-++---------------------------- Confidence: 000221330000020122102242235643763333020201100000001000010012 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: +-------+------------------------------------------+-+------ Confidence: 302010026011200101010022000000000101121000002110110403000000 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: ---------+-++++--++------------------------+++-+---++++++++- Confidence: 012003003525464103400222002000001000000000136534202465566543 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: -+--+++---------++----------------------------++--++--++--+- Confidence: 353245312232020344100021210010020111012000011233125523430252 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: --------------+-+----------------++-++--------------++++++++ Confidence: 013103200100314242003000100001111351641112012000300157696956 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: +++-+++++++++--+++++-++-------------------+-+--++++++++----- Confidence: 536274885943530395971640000000001000000300424228847548903000 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: ++--+------+++++----------+-+-+--+++------------------------ Confidence: 432140100026354400010201123233322544222113231011111000000000 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: ---------------------------+---+--+-----------+++++++-++---- Confidence: 000000000000000212022210300312230240000000000099999993972000 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: -----------+---+-+----+++---+---------------++-++---+--+---- Confidence: 002100100004113425020243511260110000000010126313401040270013 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: ------------------------++--+--------------------------+--++ Confidence: 100000000000000000003003543332123000000111100001002122143246 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: +------+---+--+++-+-----------------------+------+-+---- Confidence: 52221134332411434140010000000000000022110051200003042020 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest).

The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.

The Predicated Binding Sites between TERC and ATM
By miRanda	Structure	Match Score	Energy Score	TERC Location	ATM Location

The Predicated Binding Sites between TERC and ATM
By RIsearch	Structure	TERC Location	ATM Location	Score

The Predicated Binding Sites of ATM
RBPBD
RsiteDB
BindN	>sp\|Q13315\|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=3 Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: ------------+-----+-+++++--++-++--+-----+---+++++++-++------ Confidence: 949998999989536434737576622558576854443652547555798286645899 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: ---------------+--+-+-+-+++++++++-+------+---+--++++++-+---- Confidence: 938852263242355765635362879789777252823795489633589589367459 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: --------+--++---+---------------+-------------------+------- Confidence: 987978375425534654657329893887287234538446648899393958272422 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: ---+----------++---++++--+-----------+--+++++++------------- Confidence: 473688992983884732355442352377499427662284797863634989992879 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: -------+-+---------------------+--------------------++++++++ Confidence: 337762749597699999977993944452653482699999969593954484597768 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: +-+++++-++-----------------+++++++--++---------------------- Confidence: 525585648577369699999992242797898735646783879989999996697564 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: ++--+-++++++++++++-++-+-++++------------++------------------ Confidence: 472553555777888765346262898543795899383556324578999896892367 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: -+---+--------------------+++++--+--+----------+++++++++++-- Confidence: 252455652758369889954763228756822565599379965247878577555625 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: -+----------+--+++--+-------------------+--------+--+-+----- Confidence: 459654954948536454255874787978894746539748843882364382544777 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: --------+------+-----------++------------------------------- Confidence: 892777324672427535865666492754262348947999689884762345844995 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: ---------------+-+--+---------------++---------------------- Confidence: 448649999598927465356666598569755222454243746689989895437728 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: --------------+++--------------+--------------++-++--+--+--+ Confidence: 888599276663234565432732362448759777856567363255465324375727 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: --------------------+--------++------------++++----+--+-+--- Confidence: 888788773839999977465232542285554256654625354652234755476466 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: ----+--++++++++++--+----+----+-------------+--++---+-+------ Confidence: 387256667559874785554889488224983999998237764845253845522446 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: -+------------------------+-------++++---------------------- Confidence: 453737658765324366584542255253322256555558357977472378898999 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: --------++-++++-+-+----++--------++-++++-------------------- Confidence: 949989995736778355643276638967963463645726276969999479576735 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+-+++-----+--------------+++-++++++--+----- Confidence: 979999999937822735365552255448947997992363556356565733655693 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: -----------+++----+-----------------+----------------------- Confidence: 998986563256653529579894892389554323438894958268694697469987 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: -----+--------+----++-++++--+----+--+--------+-+---+-------- Confidence: 653386776743836563458267786465746682427752727574253535222632 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: -----------+-------------------------++-+---------+--------+ Confidence: 553864625224666499899927237763688588755563256555694388538355 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: --+++-----------------------------------------------+------- Confidence: 244558748795598399998969452333623877999653584583245258999589 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: -+----------+--------------------------+---+-+++-+-+-+------ Confidence: 855374282366437478535883489839996997488432273555462727222834 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: -----------------------------------++++++------------------- Confidence: 572452456359959896698699999994975345586762257678676842542322 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: --+---+-------+--+++-+-------+++-++--------------++-++--+--- Confidence: 544478584693824527785728858826562643289899984663267276227583 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: -------------++---------------------------------+----------- Confidence: 976999399925755444383779938994599626342426785838526387789934 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: ------------------------------------------------------------ Confidence: 982257228268878797999959958959686942698799359984424342829495 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: --------------+-++-+-++++------------------------+----+--++- Confidence: 997899979986795854274865933439999987892849488847276463645763 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: ------------+-++-------------------+------------------------ Confidence: 525339689898754432236586929996993945657222442688699726854974 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: -----------+-+++++--+--------------------------+-++--------- Confidence: 966427563326246756664688958956899995495459957685876455269247 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: --+++----------------------++++++-----+--+------------------ Confidence: 564762235679437336468939434967865342837445456789999969596857 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: ---------------++-++----------------------------------+---+- Confidence: 766839448356793543774478599286558225473499559999999762542262 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: --+-----------+--+++++++++++--+------+----++++++--------++++ Confidence: 654239358723586234577988655732533447958674777695586796237889 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: +++++-----------------+--------------------++--+++-++------- Confidence: 998742774999698973859848722567583899396826356224652563653333 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: --+++-++++++++-++------------+------+-+-----+--+---+-+++---- Confidence: 226673575567663654839579999954367254565433436444352848446447 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: ----------------+++++--------------------+---+-------------- Confidence: 849279823796254268684356748956978759829295453543385788987964 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: ----+-----------++-+-+++++------++-+-+---------++-+--------- Confidence: 366363654636325254452545442833654557653633633265666826956772 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: +---+---------+---------------++--++----------+------------- Confidence: 535356327232536848675973875862655255472393924553224727558487 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ------+-------------+-++------------------++-+-++----------- Confidence: 898889539997999956425247358259843798794875754624565429863723 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: -++-+----------------+---+------+--------+---++-+-+-------+- Confidence: 255563473466988959627526276743894469229554343652648522246768 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: --------------------------------+-++---++-+-+------+-+-+++++ Confidence: 685698567876898884339629967543224256233954847667369556255557 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: -----+-++--------++--------+--+-++++++++--+---------+--+--++ Confidence: 632266255322235347742455668572636659664773579799698856372284 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: +---+--------------------------------+------++---+--+------- Confidence: 745357975595788266868979939838397346742824355624284243388699 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: -----+--++----------------+-----------------+-++--------+-++ Confidence: 558867437556448886899678836845545564999999856447523723424387 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: ++-+++-++++++-++-++----+---+-++++++--+-----------------+++++ Confidence: 593797358646636446433425964539698682674867689959989495556587 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: +++--+--------+--------------+--------+--+-+--+---+--------- Confidence: 786246437634525724988999636575872244234664752455374875472852 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: ------+++++++++-+-++--+-----------------+++++++++-+--------- Confidence: 996776776857855274744474778767996995245377888988827364438735 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: --+-----------------------++++++++-------++---+--++--------- Confidence: 326267566926385896899687424678685536364254525446255223535997 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: ----------------------------+--+-++--+++----------+--------- Confidence: 999978945982699987999999798354472862365568639956765382399968 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: -----------------+------+---+--+---------------++---------+- Confidence: 448479599989786474662364653446359987786727834775545424555473 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: -------------------------+--+-+-+---------------+--++------- Confidence: 344289599799969999997856856656526344335835383633423653623854 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: ---+---+---+--------------+----------------+-++--------- Confidence: 37466865876583437256475276565439478966887425657754653839 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
BindN+	>sp\|Q13315\|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=3 Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: ------------+---+-+++-+++---+-++--+-----+---+-+-+++-++--+--- Confidence: 617896997756513444838186432254364855521351357152666257423467 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: -+----+--------+--+-+-+-+-+-+++++------------++++++-++-+---- Confidence: 745611365146536633425443515158364334723781567744699268155236 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: --------+-+-+---------+---------++++----------------+-+-+-+- Confidence: 866957384441426634625347893664157333315235438898393738476252 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: --+-----+--+---+---+-----+-----------+--+--+++-------------- Confidence: 283275775755243421351222633465367235631262145532434857996959 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: -----+-+-+-------------------+-+---------------+--+-+++++--- Confidence: 324347546652247689967772722324642181699998759484613176584211 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: +-+++-+-++--+----------++-+++++++++-++---------------------- Confidence: 344351345477329567975583525778688854554252638889997964484574 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: -+------------+-----+-++++++-+------+---++------------------ Confidence: 241715121112234423533354777414443678371543113767885482794657 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: -+-----------------------++++++--+--+--------+-++++-++---+-- Confidence: 142432651557369869975563158633811466565378765535556235121337 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: -+----------+---+-----------------------+--++----+--+++----- Confidence: 458324822525624142353962568877794644446754533671264344433636 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: --------------------------+++-+-+--------------------------- Confidence: 583768485773657244884364344561465527745787858978973468843552 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: ++--+------------++-+-------------+--------------------+---- Confidence: 364545799398916286425323155338362351322254644688989796445526 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: ------------+---+---+-+---+-----------------------------+--+ Confidence: 777399276563412174235631184329738863657478645554924431674326 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: --------+-+------------+--+--+----------+----+++---+--+-++-- Confidence: 676777544437588857242233335363264237363436321453263442555556 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: -------+---++++++--+----+----+------------------------------ Confidence: 288436843336753643341577466325772698487136514911234132432445 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: ------------------------------------------------------------ Confidence: 572546557766114367574462263464542531456347465877253268798968 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: --------------+-+-+--+-++--------------+--+---------------+- Confidence: 847969691442114253732465627768965638363525461948689278524442 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+--++--+--------------------------+--+----- Confidence: 767558989827815634314643377146732872873153243634321764435694 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: ---------+-++---+-+----+-------------+---------------------- Confidence: 852742141444443348566783383698787412337784748265575567798875 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: -----+----------------------+----+-------+------------------ Confidence: 231274334453711671751443418543566572225763735273676475436442 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: --------------------------------------+--------------------- Confidence: 556735535444888688899858527674279488624434126432672577738682 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: ---++-------------------------------------------+----------- Confidence: 324545466998498587984849786875987797999686476556343326689688 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: -------------------------------------------+---------------- Confidence: 824253485287469268748987667659792898698467546333776699865946 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: ----------------------------------------------------------+- Confidence: 594866987177748764695699998998968795789889898898575983635441 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: ----------------------------------------------------+--++--- Confidence: 743687366787963975355589999974432114197788995889632251175763 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: ------------------------------------------------------------ Confidence: 794988655956864755575475853655567449666668978968799789888977 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: ------------------------------------------------------------ Confidence: 887577367789999897889769999989798856988899689696314353858897 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: --------------+--------------------------------------------- Confidence: 999898877885884843358336148579887996994849488699748576478475 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: ------------------------------------------------------------ Confidence: 873436487999498799898999959955872853755233312486597666724733 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: ------------------------------------------------------------ Confidence: 515115562252542442896899958967989998499897968875978999699467 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: ------+-----------------------+----------------------------- Confidence: 771313524224516677999979678323411452822852877774553436164735 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: ---------------------------+-------------------------------- Confidence: 538638459798995667326378279324754655675598789889999999698749 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: ------------------------------------------------------------ Confidence: 989989899988998998877264447487678969979899647725885998282223 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: +----------------------------------------------------------- Confidence: 612242687689785956438618833347381578596758956564548626886987 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: ------------------------------------------------------------ Confidence: 767668778877659979989989948978797995586695351242595698857355 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: -------------------------+---------------------+------------ Confidence: 749679979998897854334657955735689879969595875334453789999975 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: ------------------------------------------------------------ Confidence: 376335633578877648835544365951982361667677999996794999987864 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: ------------------------------------------------------------ Confidence: 677567268256831917889988988986577476875674435525775758775797 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ---------------------------------------------+-------------- Confidence: 688577127753664433456934689489888558387285233333246429866944 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: ------------------------------------------------------------ Confidence: 734737764755877928636346238763997898679976785254671773848869 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: ------------------------------------------------------------ Confidence: 768478887777788896747839878667646564555355376858779475845844 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: ------------------------------------------------------------ Confidence: 998494745978989995375789676262154532436175398899999979938626 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: ------------------------------------------------------------ Confidence: 469579987697999887767669939849698799978947793478359352539858 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: ------------------------------------------------------------ Confidence: 426852772589969894799558975985526338757984583233535834335522 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: -------------------------------+-----+-----------------+-+++ Confidence: 315436973685387577368887998893342426444967898768475474341354 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: -----------------------------------------------------+++++++ Confidence: 112554879889975834987889546572751543354571722375283843658435 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: ----+-+--+--+---+-----+-----------------------++--+---+----- Confidence: 261834323552343753112262754886995993354224252244145233411543 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: -++-------------------------++++---------------------------- Confidence: 443435643943545736687355446334344234362294267598354268515786 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: -------------------------------+-++---------------++--+----- Confidence: 698978954761488677898899488616335441334647636416127722595987 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: ------------------------+---+--+--------------------------+- Confidence: 444437284536872461331331322352354777885863461783445547416642 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: -------------------------+---------------------------------- Confidence: 254799789499959647773546747314234488775667777998646235626896 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: ---------------+-+-------------------------------------- Confidence: 78468931853172164426577587388539899958966821532435424818 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
RNAbindR	>Q13315\|ATM Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: -+----------+--++++++++++----------------------------+--+--- Confidence: 252001102001541777959786822421201011010000101121031045215431 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: --------------------+--++-+-+--++--+---------+++++++++++---- Confidence: 031011100300120322126445845364367045114102421675587695762341 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: --------------------------+-------+------------------------- Confidence: 011001001000001120044040008202303253240323331100000011012203 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: --------+-------+------------------------------------------- Confidence: 201431125011001352212221132100000000000000014031032001001010 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: -----------------------------------------------+-+---------- Confidence: 120113141202401010000000000012124201200010020105153232000000 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: --------+----+----------+--++++++--------------------------- Confidence: 011021325321460101002004543787765412340210221040000000100000 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: ---------------------+++++++-+------------+----------------- Confidence: 000000010000212011023578788845342200002003512012011000000000 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: ---------------------------+-++-+++-++---------------------- Confidence: 110110020000000000000000124725736853861200002001100000000000 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: ------------------------------------------------------------ Confidence: 011113001000211203100001211023101210010030001000010011233211 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: ------------------------------------------------------------ Confidence: 000100000000010100000000002212412441014110000000000000010001 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: -------------+---------------------------------------------- Confidence: 001010000300052214413101220100000000000000000000000001000000 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: ----------------+---------------------------------------+--- Confidence: 000000000000000152113000100000010000000000000001011032016204 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: ------------------------------------------------------+----- Confidence: 211421242122200111001123123201400120012131012001000401523000 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: ------------------------------------------------------------ Confidence: 000010002012121111011001300122001000000000010022000000000000 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000001420000001001100010 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: ------------------------------------------------------------ Confidence: 010000000000110111300000010000000000000100001000000100010020 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+------------------------------------------ Confidence: 000000000010010006232312000000012001001000000000000000000000 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: -----------++++++-++---+------------------------------------ Confidence: 100300111245668892754126100000100120000000000010000001020013 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: ----------+------------------------------------------------- Confidence: 132302131152023001000000000000000100100000000000000000010000 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: ------------------------------+---------------+------------- Confidence: 000000011111100200120021331112601320010000111054002100020024 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: ------------------------------------------------------------ Confidence: 233420000000000000000000000000000000100000000000210010001311 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: ------------------------+----------------------------------- Confidence: 021400000100000000010000530141003000000000000010000000000000 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000021234 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: ------------------------------------------------------+++-++ Confidence: 112100000000000010211000000000111000000010002001112343779466 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: +-------------------------+--------------------------------- Confidence: 613221130000000001101120025004101200010000000000000000010000 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000012000100000000110000000000 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000121120000000000000100100010200011000 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: -----------------------------+--+--+----------------------+- Confidence: 000000000000000000001000240035126025412333143302100030111054 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: ------------------------------------------------------------ Confidence: 121111001000000000000000000000000001000101011101000000100210 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: ------------------------------------------------------------ Confidence: 101220110110100000100000221442133001000000000000000000000000 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: ------------------------+--++------------------------------- Confidence: 011240240011001111323402611561021013104400440001000100110021 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: ------------------------------------------+---+---+-----+++- Confidence: 001200000000000000000000000000000000000002543284205113315853 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: +++-+----------------------++--+++-------------------------- Confidence: 855352323323332033121134123552356622111010010000000000000000 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000010201013000211201000000100101300 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: ------------------------------------------------------------ Confidence: 421010000000000000000010042121111100000000000010010010000010 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: +---++-+------------------+--+--++-+-+---------------------- Confidence: 512475261100000000011122325148146527254212000000100000011001 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: --++--++------+-+------------------------------------------- Confidence: 225742770332118353341000000000000100101000021101011023122203 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ----++-++--+----+----------------------+--+--++-+---+------- Confidence: 433385465015011250011000100010001011222611642554510170001000 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: -----------------------------+------------------------------ Confidence: 000000000001001031232323333326201100000000000000002002130302 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: ---------------------------------------------------+-------- Confidence: 103110123202010001200020000113110310001230203042411511011011 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: ------------------------------------+--+-+------------------ Confidence: 011201021131011001210010000001111234524525410000000000000011 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: ------------------------------+----------------------------- Confidence: 110131133204012100100010030211523320100000001000221214200200 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: -----+---------------------------+-------+--------------+--- Confidence: 240027014110012314400130003001132740133015134222211211145142 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: -+--------------------------------------------------------++ Confidence: 151123011011112113200001000101231231031014001110210022142465 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: -++-+-------------------+------------+---++-+---+----+++++++ Confidence: 467454342311022013001110522211143444274246536102514439898987 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: +-+-+-+++++++---+-++++++-----------------+++++++++++++++-++- Confidence: 635383897968734484767687432122011003312336756877969899874863 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: ++---------+---------------+++++-++++-+--------------------- Confidence: 753240024025314012100124421575782665746302211100110211241201 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: -----+-+---+-----+------+---+++++++++-++--+------+++-++----- Confidence: 110035454315201015412213533386765986648831542144488716524021 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: ------+---+--------------+++++++-----------++++++----------- Confidence: 212102612273143112221134455986573111211032256658744111141132 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: ------------------------------------------------------------ Confidence: 211101410421033241323011130121111000000000000000000000001001 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: -------++--+--++----------+++-+----+---++--+--+++++++++-- Confidence: 213243265029435933421143237563724235431851494476758988940 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
Pprint	Sequence: MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAV Prediction: -----------------++-+-+++---+--+---------+--++-++++--+-+---- Confidence: 133001000000101213724356632042232020221024126334555114142200 Sequence: FRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQEL Prediction: ---------------+------+++-+-++-++------------+-+++++-+-+---- Confidence: 010102000101100513323244334235244223220002100424999736241210 Sequence: LNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQ Prediction: ---------------------------------+------------------------+- Confidence: 000001201112200231001030000000022522000000000000000000003232 Sequence: DVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFL Prediction: +-------++++--++++++--------------------+--++++++----------- Confidence: 300310027443114644343322001100100030120253354454513100000000 Sequence: KTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK Prediction: ----++++--------------------++--+-----------------++++++++-- Confidence: 100156442301300000000000000044123100000000000001027554743412 Sequence: GAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNED Prediction: +----------------------++-+-++++++++++---------------------- Confidence: 313110100000000000000113323365776865673300000000000000000000 Sequence: TRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI Prediction: ------+--+-+--------+-++-+++-+-----------+------------------ Confidence: 321020433433011000215254254304100000000034020010000000000000 Sequence: SKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDL Prediction: -----------------------+++++-+---+-------------+++++++------ Confidence: 021132000000000000002003545623331323333200002135644543323110 Sequence: LKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC Prediction: -+----------++------------------------------------+--+++---- Confidence: 050010000233443231332001210000000000010010000012334233340000 Sequence: CLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILH Prediction: ---------------------------+--+++--------------------------- Confidence: 000000000101110313012012302512435100000000000010000000000000 Sequence: SNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKM Prediction: +---+------------+------++-----+--+------------------------- Confidence: 401040000000012024203012431001041051000010000000000000000000 Sequence: DFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSR Prediction: --------------+-+-+++------+-------------------------------+ Confidence: 000000100010334253456222111400010000000000001002002000001005 Sequence: LLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMM Prediction: --------------------------------------------++-++-++--+-++-+ Confidence: 010130022230000000000201100002000202000022025625435531415824 Sequence: QLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMED Prediction: ----+---++-++-----------+----------------------+-----------+ Confidence: 311142005306721020111210400021101100000300000036010301021104 Sequence: DTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDM Prediction: -------------------------------+---+++---------------------- Confidence: 211000020000010000010000000000041114432110000000000000000000 Sequence: LKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYP Prediction: --------------+---+--+-------------------------------------- Confidence: 010001001102123323500411210000000000000000022000000000000000 Sequence: LPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLT Prediction: -----------------+-+++-++---+------+---++++++++-++-+-------- Confidence: 000000000000000014247624410240000005103553555552543310110012 Sequence: VIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLAD Prediction: ---+-----+-+-----------+------------------------------------ Confidence: 011412010523202021100014000000000000000000000000010001000002 Sequence: NHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAEN Prediction: --+-----------+---+-+-+-++--+--------------+---------------- Confidence: 315102300001104003434362583253011300000002041201012111111000 Sequence: PETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSET Prediction: ----------------------------------------+--++--+------------ Confidence: 000000000110000000000010020000000000123342274034202200000002 Sequence: FGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLV Prediction: ---+-------+---------------------------------+-++----------- Confidence: 102530000004000000000010000000000000000001002505411020000000 Sequence: IRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYD Prediction: --------+------------------------------+---+--++-+---------- Confidence: 010000103301200000000000000010000000200402362343233321021100 Sequence: MLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPH Prediction: -----++--+-----------------------------------------------+-- Confidence: 003123300400000000200000000000011000130000100000000001000322 Sequence: FPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILK Prediction: --------------+--------------+-------------------+-+-------- Confidence: 000000000000023313010110000004012222000001000010143422212001 Sequence: IYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQ Prediction: ----------------+++------------------++-----+--------------- Confidence: 002000000010012253410100000001000320055330005100000011010000 Sequence: VCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIK Prediction: -----------------------------------------------+++++---+---- Confidence: 001000020031000001000000020000000002000000000004554322240001 Sequence: LLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQ Prediction: -----------+--+-------++--++-------------------------+------ Confidence: 000200010005105011320043314300000000000000000000000034322322 Sequence: LELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGP Prediction: ------------+++--++-+------------------+-------------------- Confidence: 000000000203543325524210010101002001213533110001003000000003 Sequence: IDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNI Prediction: -------------------------------------------------+---------- Confidence: 020300000012200211000000000000000001200010000000031202110000 Sequence: LATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSE Prediction: ------------------------+----+------------------------------ Confidence: 001100220010000000000000303005332102000010000001000020100202 Sequence: NHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRN Prediction: --+------------------------+-----------------------------+-- Confidence: 214010100000012222211001200401000020031100000000000000122333 Sequence: LLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQK Prediction: -----------+--+------+++--+-------++------++-------------+-- Confidence: 100000000024223201102635323301000134120212440030000000000310 Sequence: RPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEG Prediction: ----++--------------------------------------+--------------- Confidence: 322243100000000010000010030311000000200021124222111122000011 Sequence: SQNTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEA Prediction: ----------------------------+--------------+---------------- Confidence: 000120000000000001000000010040020001000102032130000000000000 Sequence: MWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHY Prediction: -------+--------++++-----+---------------------------------- Confidence: 020001030000003243852133060100200000000000000000101001000000 Sequence: QAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCK Prediction: ------------------------------------------------+-+--------- Confidence: 010011020000000000000001110000000101001000000202403310000000 Sequence: RSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQ Prediction: ------++--------------------------+-+-+--+++-+++-++--+------ Confidence: 000022640010000000000000000000322243334224463466344233121001 Sequence: EPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQ Prediction: ----------------+----------------------+--++++++++++++------ Confidence: 011001120000000032012112231000010221200603897994595475301002 Sequence: YNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRV Prediction: ----------------------+--+---+-----------++++++-----++-----+ Confidence: 010002111322000000001232052024100000011116864550111053112124 Sequence: CGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQR Prediction: +--+--+---------------+------+---++------------------------- Confidence: 403300410000000000001032011013222441220001100000000200000031 Sequence: IENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRK Prediction: ----------------------+--++++-++---------------------------- Confidence: 000221330000020122102242235643763333020201100000001000010012 Sequence: RFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLM Prediction: +-------+------------------------------------------+-+------ Confidence: 302010026011200101010022000000000101121000002110110403000000 Sequence: YQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARR Prediction: ---------+-++++--++------------------------+++-+---++++++++- Confidence: 012003003525464103400222002000001000000000136534202465566543 Sequence: SRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKT Prediction: -+--+++---------++----------------------------++--++--++--+- Confidence: 353245312232020344100021210010020111012000011233125523430252 Sequence: QRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPK Prediction: --------------+-+----------------++-++--------------++++++++ Confidence: 013103200100314242003000100001111351641112012000300157696956 Sequence: IIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPL Prediction: +++-+++++++++--+++++-++-------------------+-+--++++++++----- Confidence: 536274885943530395971640000000001000000300424228847548903000 Sequence: SQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVF Prediction: ++--+------+++++----------+-+-+--+++------------------------ Confidence: 432140100026354400010201123233322544222113231011111000000000 Sequence: MDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINE Prediction: ---------------------------+---+--+-----------+++++++-++---- Confidence: 000000000000000212022210300312230240000000000099999993972000 Sequence: QSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRN Prediction: -----------+---+-+----+++---+---------------++-++---+--+---- Confidence: 002100100004113425020243511260110000000010126313401040270013 Sequence: SQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQ Prediction: ------------------------++--+--------------------------+--++ Confidence: 100000000000000000003003543332123000000111100001002122143246 Sequence: SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV Prediction: +------+---+--+++-+-----------------------+------+-+---- Confidence: 52221134332411434140010000000000000022110051200003042020 *Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *Confidence: from level 0 (lowest) to level 9 (highest).

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RAID

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