The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00001595
RNA/Protein Symbol 1:RNU7-1(U7)
RNA/Protein Category 1: snoRNA
RNA/Protein Symbol 2: LSM11(Lsm11)
RNA/Protein Category 2: Protein
Validated Method:
Tissue: HeLa cells 
PMID: 12975319 
Detail description:

Thus, the U7-specific Lsm11 protein not only specifies the assembly of the U7 Sm core but also fulfills an important role in U7 snRNP-mediated histone mRNA processing. 

The Predicated Binding Sites between RNU7-1 and LSM11
By miRanda Structure Match Score Energy Score RNU7-1 Location LSM11 Location
The Predicated Binding Sites between RNU7-1 and LSM11
By RIsearch Structure RNU7-1 Location LSM11 Location Score
The Predicated Binding Sites of LSM11
RBPBD
LSmx1
RsiteDB
BindN
>sp|P83369|LSM11_HUMAN U7 snRNA-associated Sm-like protein LSm11 OS=Homo sapiens GN=LSM11 PE=1 SV=2

Sequence:    MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYE
Prediction:  ---+-++-+++++++++++++++----+------------+-----+-------------
Confidence:  545437529877589859788493232553787999828478326345264675478675

Sequence:    SFLRTGVRGGGRGRGRARGAAAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAK
Prediction:  ---+---+++++++++++++--++--+--++++++++++++++-----+--+-++-----
Confidence:  357822499999998949452347344227599999999664533232842777665752

Sequence:    EEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLR
Prediction:  -------++++++++++++++++---+-------------+--+---+-+---+--+--+
Confidence:  754444265599999999956964527776347346329366774565755355335558

Sequence:    GVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEAD
Prediction:  -------------------------+++---+-+-++++----+---+---+++++++++
Confidence:  564277999993975999458432275453273647456627266755826575678976

Sequence:    SKSAVEDSTLSRYSQTSTWKLASVWGRADTGRGSHKRSRSVPSSLQASAREESRSELSGR
Prediction:  ++------+-++++++++-+--+---+--+++++++++++++++-+++-+++++++++++
Confidence:  562345326348788765254647239327797999979846773757287578566869

Sequence:    TTRTDGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
Prediction:  ++++++++-+++-++-++-+++++++++++++----------------+-----------
Confidence:  789885773666258366299999999999893323274225952969497589996994


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|P83369|LSM11_HUMAN U7 snRNA-associated Sm-like protein LSm11 OS=Homo sapiens GN=LSM11 PE=1 SV=2

Sequence:    MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYE
Prediction:  +--+-++-+++++++++++++++-----------------+--+-++-+-----------
Confidence:  412626418646365558566473362254669687518266152442432431155655

Sequence:    SFLRTGVRGGGRGRGRARGAAAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAK
Prediction:  ---++--+++++++++-++-+--------+++++++++++--+----+++++-++-----
Confidence:  147532188889798815313421453325478897888533312115836847553672

Sequence:    EEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLR
Prediction:  ------++-++++++++++++++--++------------++--+---+-+-+-+--++-+
Confidence:  663422471598889989944852346343123232116472671254754466118336

Sequence:    GVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEAD
Prediction:  --------------+--------+++++--++-+-+--+----+---+---+++++++--
Confidence:  233267757851234566275435463432462444124528233644614434446323

Sequence:    SKSAVEDSTLSRYSQTSTWKLASVWGRADTGRGSHKRSRSVPSSLQASAREESRSELSGR
Prediction:  -++-----+--+---++--+----+-+--+++++++++++-+++---+-+---+---+-+
Confidence:  143677443425122632235315427325396969878743346123541316122516

Sequence:    TTRTDGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
Prediction:  +++++--+-+++-++--+-+++++++++++++--------++------+-----------
Confidence:  446532144444366334378778999996781222165244821625444378782661


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>P83369|LSM11
Sequence:    MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYE
Prediction:  -----------+-------------------+---------------+-++++++-----
Confidence:  231224113315224422100141112324171012033121221336389667724433

Sequence:    SFLRTGVRGGGRGRGRARGAAAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAK
Prediction:  -----------+-+---------------------------------+--+--------+
Confidence:  311231213225352442241321101111132001111001110245425402421135

Sequence:    EEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLR
Prediction:  -------+--+++--+-+++--+----------++-+---+---++++++++++++++++
Confidence:  111104353475533547874460002000022553621354245689796989999988

Sequence:    GVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEAD
Prediction:  ++--++-++++++-+-----------++++++--++-++---------------------
Confidence:  984458457569715000240224346895884475375420240002010110000111

Sequence:    SKSAVEDSTLSRYSQTSTWKLASVWGRADTGRGSHKRSRSVPSSLQASAREESRSELSGR
Prediction:  ----------------------------------+-------------------------
Confidence:  010000002101202101020310101010012254223110211201100000011023

Sequence:    TTRTDGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
Prediction:  -----------+------------++++++++++++++++++-++-+-+--+----+--+
Confidence:  113212244136214122114433657677585666866797177052824541016026

Sequence:    
Prediction:  -
Confidence:  0

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYE
Prediction:  ---+++++++++++-+--------------------------------------------
Confidence:  233646467777453432212020000000000000000000010001000000000000

Sequence:    SFLRTGVRGGGRGRGRARGAAAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAK
Prediction:  -----++++++++++++++++++-------+++++++++-+++-++--+--+-++-+-++
Confidence:  200326898999999989974641000023777794666245524331422416526236

Sequence:    EEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLR
Prediction:  +++-++++++++++++++++++++--+--------+-+-++--++------+-+++++++
Confidence:  653355686899899999965554205022112213241472153232223415667546

Sequence:    GVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEAD
Prediction:  +----------+-------------------------------+-------+-+-++---
Confidence:  330200010224000000000000100221231312111100040000021535244321

Sequence:    SKSAVEDSTLSRYSQTSTWKLASVWGRADTGRGSHKRSRSVPSSLQASAREESRSELSGR
Prediction:  ---+--------+---------+---++++++++++++++++++-+---+--++-++-++
Confidence:  032300000002422212220131336668999997967536451412041144144344

Sequence:    TTRTDGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
Prediction:  -+++--++-++---+--+++++++++++++++-+--+-----------------------
Confidence:  356332643453114133558787975887463322400233003021200010012013

Sequence:    
Prediction:  
Confidence:  

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.