The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00001594
RNA/Protein Symbol 1:RNU7-1(U7)
RNA/Protein Category 1: snoRNA
RNA/Protein Symbol 2: LSM10(Lsm10)
RNA/Protein Category 2: Protein
Validated Method: Immunoprecipitation
Tissue: HeLa cells 
PMID: 11574479 
Detail description:

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. 

The Predicated Binding Sites between RNU7-1 and LSM10
By miRanda Structure Match Score Energy Score RNU7-1 Location LSM10 Location
The Predicated Binding Sites between RNU7-1 and LSM10
By RIsearch Structure RNU7-1 Location LSM10 Location Score
The Predicated Binding Sites of LSM10
RBPBD
LSmx1
RsiteDB
BindN
>sp|Q969L4|LSM10_HUMAN U7 snRNA-associated Sm-like protein LSm10 OS=Homo sapiens GN=LSM10 PE=1 SV=1

Sequence:    MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
Prediction:  ----++-+-++---------------+-++---+-------+----------+--+-+++
Confidence:  878256462456255499999465246657466567363256852979687957775764

Sequence:    DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPK
Prediction:  -+--+-----------+--+------------+-----------++--++++++------
Confidence:  262442829959693572682759799848224863696775296422596748333332

Sequence:    NCK
Prediction:  +-+
Confidence:  447


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|Q969L4|LSM10_HUMAN U7 snRNA-associated Sm-like protein LSm10 OS=Homo sapiens GN=LSM10 PE=1 SV=1

Sequence:    MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
Prediction:  ---+++-+-+----------------------------------+-------+--+----
Confidence:  435544544426433599899569674862637247257241733737262838848322

Sequence:    DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPK
Prediction:  -++-----------+-+--++-+------------------++-+++++++++++----+
Confidence:  364413869869373462745536665839462984796653578855787648722216

Sequence:    NCK
Prediction:  +-+
Confidence:  618


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>Q969L4|LSM10
Sequence:    MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
Prediction:  ------++-++++++++-+--++--++--+-+-+--------------+-+--------+
Confidence:  224134664757768863921751365215351740320222014241517221420315

Sequence:    DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPK
Prediction:  -+++++++----+-+++++++-+---------------++++++++++++++++++++++
Confidence:  367787550243749798788261434230020001106758888888998999999999

Sequence:    NCK
Prediction:  +++-
Confidence:  9990

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
Prediction:  -+++++---------------+-------+---+------++------+---+-----++
Confidence:  243543120210002000000303011004030520120144003223420040000254

Sequence:    DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPK
Prediction:  ++++-++---------+--+--+-------------------+-++++++++-+++-+--
Confidence:  677425300130200130240041120130020001000003608869994739353513

Sequence:    NCK
Prediction:  +++
Confidence:  634

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.