The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00001593
RNA/Protein Symbol 1:SCARNA10(U85)
RNA/Protein Category 1: snoRNA
RNA/Protein Symbol 2: GAR1(Gar1p)
RNA/Protein Category 2: Protein
Validated Method: Immunoprecipitation
Tissue: COS7 cells 
PMID: 11157760 
Detail description:

We have identified a novel evolutionarily conserved snoRNA, called U85, which possesses the box elements of both classes of snoRNAs and associates with both fibrillarin and Gar1p. 

The Predicated Binding Sites between SCARNA10 and GAR1
By miRanda Structure Match Score Energy Score SCARNA10 Location GAR1 Location
The Predicated Binding Sites between SCARNA10 and GAR1
By RIsearch Structure SCARNA10 Location GAR1 Location Score
The Predicated Binding Sites of GAR1
RBPBD
RsiteDB
BindN
>sp|Q9NY12|GAR1_HUMAN H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens GN=GAR1 PE=1 SV=1

Sequence:    MSFRGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNK
Prediction:  ---++++++++++--+++++++++++++-+--++++++++-+++++++++++++++++++
Confidence:  725854598756922577657966898629225576876729655976659766977578

Sequence:    GQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQL
Prediction:  -+-+++--+-------------------++--++--+-----+-----------------
Confidence:  262754456999999995999999882654236763573759475335256297586979

Sequence:    RDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGR
Prediction:  -------------+-++-++-++------------+---+++-+++++++++++++++++
Confidence:  278282938233372553775456286663864956564855289687988998898889

Sequence:    GGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRGH
Prediction:  +++++++++++++++++++++++++++++++++++--
Confidence:  9988989898765956956776659559688695932


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|Q9NY12|GAR1_HUMAN H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens GN=GAR1 PE=1 SV=1

Sequence:    MSFRGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNK
Prediction:  -+-+++++++++++++++++++++++++-++++++++++++++++++++++++++++-++
Confidence:  151864498758975688858864688618558888888859865987589866986176

Sequence:    GQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQL
Prediction:  ------------------------------------+-+---------------------
Confidence:  223124366799986792777778992643484162724548196217332264153489

Sequence:    RDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGR
Prediction:  -------+-----+-+-------------------++--+--++++++++++++++++++
Confidence:  245171848222535412155448265762342734342721558788977798998879

Sequence:    GGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRGH
Prediction:  +++++++++++++++++++++++++++++++++++++
Confidence:  9878986598877977987898769769888698966


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>Q9NY12|GAR1
Sequence:    MSFRGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNK
Prediction:  +++++++++++++--------+++-++++++++++++++++++++++++++++++++++-
Confidence:  688979888655633434344565465666778889899989999999898889888874

Sequence:    GQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQL
Prediction:  ++---------------------------------++++-+-+-----------------
Confidence:  663223000000000003000010000003001116767381511322102201320230

Sequence:    RDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGR
Prediction:  ----------------+------------+-----+---++-++++++++++++++++++
Confidence:  320100040011132452301121101026132146313654757888999999999999

Sequence:    GGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRGH
Prediction:  +++++++++++++++++++++++++++++++++++++-
Confidence:  99999999999999999999899999899999999890

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MSFRGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNK
Prediction:  ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
Confidence:  455579799999899999999657698989899999999979799999999999999986

Sequence:    GQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQL
Prediction:  -+++-+--------------------+---------------------------------
Confidence:  353624232000000000010000003000000000201000000010000000200000

Sequence:    RDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGR
Prediction:  -------+------+---+--------------------+++++++++++++++++++++
Confidence:  000000052102215202400000012000002010001966999999999999999999

Sequence:    GGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRGH
Prediction:  +++++++++++++++++++++++++++++++++++++
Confidence:  9999999999999999999999999799999997856

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.