| Detail-Interactions: | |
| RAID ID: | RPI00001592 |
|---|---|
| RNA/Protein Symbol 1: | SCARNA10(U85) |
| RNA/Protein Category 1: | snoRNA |
| RNA/Protein Symbol 2: | FBL(fibrillarin) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | Immunoprecipitation |
| Tissue: | COS7 cells |
| PMID: | 11157760 |
| Detail description: | We have identified a novel evolutionarily conserved snoRNA, called U85, which possesses the box elements of both classes of snoRNAs and associates with both fibrillarin and Gar1p. |
| The Predicated Binding Sites between SCARNA10 and FBL | |||||
| By miRanda | Structure | Match Score | Energy Score | SCARNA10 Location | FBL Location |
| The Predicated Binding Sites between SCARNA10 and FBL | ||||
| By RIsearch | Structure | SCARNA10 Location | FBL Location | Score |
| The Predicated Binding Sites of FBL | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|P22087|FBRL_HUMAN rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens GN=FBL PE=1 SV=2 Sequence: MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG Prediction: -+---+++--++-++-++-+++++++++++++++++++++++++++++++++++++++++ Confidence: 753226493276249256279579689557887949888896959777777778898795 Sequence: GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE Prediction: +++-+++++++++++++++++++++------+-------+---------------+-+-- Confidence: 664368869999999899899858574624455667676772744683247636352542 Sequence: KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI Prediction: ++-+-+----+---+--+--+-+--------------+---+--+----+-++------- Confidence: 667555356457324735247256748985697383853646775764562665249469 Sequence: VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP Prediction: -------------++--+------++++---------+++++-+---------------- Confidence: 877777949977346247466252767626669968774466256889999999979725 Sequence: DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE Prediction: -+++----------+---------+------------------++-++-+-+-------- Confidence: 344676464832467367366839473472325265686932867344253543347362 Sequence: PYERDHAVVVGVYRPPPKVKN Prediction: ---+--------++++++-++ Confidence: 324575787757585658474 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|P22087|FBRL_HUMAN rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens GN=FBL PE=1 SV=2 Sequence: MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG Prediction: -++++++++++++++++++++++++++++++++++++++++++-++++++++++++++++ Confidence: 275636595576668655779879889876887979887595819767575557777886 Sequence: GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE Prediction: +++++++++++++++++++++++++----++++----------------------+-+-- Confidence: 676576537779687789778844363413453228368155764584217323352452 Sequence: KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI Prediction: ++------------+-+++++++-+--------+-+-++--+--+------++-++---- Confidence: 448656799735615436447791315871382453244335353525422443467328 Sequence: VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP Prediction: -------------++--+-------++++--------+---+-+---------------- Confidence: 539625738442146344677476244466768853561234356987484676736627 Sequence: DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE Prediction: ---+----+-----++--+-----+----------------------------------- Confidence: 225357544722255523454824651161228757887957934914526363326273 Sequence: PYERDHAVVVGVYRPPPKVKN Prediction: -----+------+++++++++ Confidence: 214345595622684677565 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>P22087|FBL Sequence: MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG Prediction: ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 698999999999999999888889969878898889899898878568687778678897 Sequence: GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE Prediction: +++++---++++++-++++-+++++---+++++++-++----------++---------- Confidence: 787554446656873658547655634378878782562432244104582422122212 Sequence: KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI Prediction: --------------+-+++++++++++--+--------+-++--++--++++--++-+-- Confidence: 410200000130248388999995588118201222136257415542576644881631 Sequence: VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP Prediction: -----+-++--++++--+----------+---+-----+----+---------------- Confidence: 103345266335669406301101124251125014347334260001001000010433 Sequence: DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE Prediction: ----------+-+-+++++-----++++++-----------------------------+ Confidence: 100200024053517656721232758765442412121031014111010001102235 Sequence: PYERDHAVVVGVYRPPPKVKN Prediction: ++--++------+++++++++- Confidence: 6541561023347978885770 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG Prediction: ------++++++++++++++++++++++++++++++++++++++++++++++++++++++ Confidence: 223321454676779799899999999999998999999999999999999999999898 Sequence: GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE Prediction: +++++++++++++++++++++++++------++------+--------+--+++++++-- Confidence: 999999989999999999999993611000064100200500000200403347565612 Sequence: KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI Prediction: ++-+------+--++-++++++++-+---++--+-++++-++--+++--+++-------- Confidence: 360500111250249265699696150015402418658235215541334420010010 Sequence: VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP Prediction: -----------++-++-+---+---++++---------++-+++---------------- Confidence: 000000000016628507200410353662000000016406782000000000000303 Sequence: DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE Prediction: ---+-----------++-----+-+++--+-+---------------------------- Confidence: 130400020001122533101161636115140000000000000000000220000000 Sequence: PYERDHAVVVGVYRPPPKVKN Prediction: -+---------++++++++++ Confidence: 240000000004896897576 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.