| Detail-Interactions: | |
| RAID ID: | RPI00001590 |
|---|---|
| RNA/Protein Symbol 1: | RNU7-1(U7) |
| RNA/Protein Category 1: | snoRNA |
| RNA/Protein Symbol 2: | COIL(coilin) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | Co-RNP Immunoprecipitation |
| Tissue: | |
| PMID: | 9763457 |
| Detail description: | By coimmunoprecipitation we show that coilin and the U7 snRNP can form a weak but specific complex in the nucleoplasm, which is dependent on the special U7 Sm-binding site. |
| The Predicated Binding Sites between RNU7-1 and COIL | |||||
| By miRanda | Structure | Match Score | Energy Score | RNU7-1 Location | COIL Location |
| The Predicated Binding Sites between RNU7-1 and COIL | ||||
| By RIsearch | Structure | RNU7-1 Location | COIL Location | Score |
| The Predicated Binding Sites of COIL | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|P38432|COIL_HUMAN Coilin OS=Homo sapiens GN=COIL PE=1 SV=1 Sequence: MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY Prediction: ----++-+-+---------+-------------+-+-----------+----+------- Confidence: 766246485674772534364342996999893845772899368256453255747794 Sequence: LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE Prediction: ----------+-+--+-----+-+---+--------------+-+-++++++-------- Confidence: 966878335253847584455776754467665386722555575599488845276784 Sequence: ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA Prediction: ------+++++++++++++++---------------+-+++++++++++--+------+- Confidence: 733423867899897968975242886976267242638999999996823543542242 Sequence: KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS Prediction: ++++++++++++++++++++++++-+--+-----++++++++-+++--+-+++++++--- Confidence: 899999997976789969989868255645353364888989297533828986847422 Sequence: KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF Prediction: +++++++++++------+--+++-+---++++++--+--++-++++++++--+---+--- Confidence: 768779888542534466235575632476666742525462668687875386785855 Sequence: SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ Prediction: +-++++++++++++++++++----------+++--------+-------+-+++++++++ Confidence: 547589699999989875763425635643564333667585287323393966854766 Sequence: TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG Prediction: +-+++++++++++++++-++-+++-+---+--+++-+-------++-+++++++++++++ Confidence: 544664488868965572652756465335439474766367436438697898989796 Sequence: HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK Prediction: +--+----++++++++----------++-------++++-+------------------- Confidence: 626544638787889522726662425557333526676352786998784356438864 Sequence: LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV Prediction: ----++++-+--------+--+++--+--------------+---+-------------- Confidence: 895954552524234232754455224238488983253546333566683766378699 Sequence: EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA Prediction: -------++-+---------------++++++++-- Confidence: 658734454847986899894996425787876524 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|P38432|COIL_HUMAN Coilin OS=Homo sapiens GN=COIL PE=1 SV=1 Sequence: MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY Prediction: -------+-+----------------------++-+------+--+-----+-------- Confidence: 455444467553464423433322874957474437451386466421142421547796 Sequence: LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE Prediction: ---------------------+------------------------++-+++--+----- Confidence: 959987224135189266346461653468967799976465233374276642377487 Sequence: ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA Prediction: ------++++++++++--------------+----+---++++++++------------- Confidence: 667584344678465442234584889976345153241455586542256587785454 Sequence: KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS Prediction: +-++++++++--+++++++-+---------+-+++-+-++-+--------++-------- Confidence: 414545544432565534423322636611413433414423324633134724235857 Sequence: KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF Prediction: ----------------------------+------------------------------- Confidence: 663142234576889684995324234232113463254447643221248476574522 Sequence: SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ Prediction: -+++-+-------------------------------------------+-+-------- Confidence: 234425212333323246557768988663322547687794475844334343467351 Sequence: TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG Prediction: --+----+-+-++--------+---+---+-++++++--+--+++--+++++++++++++ Confidence: 243113351435512111214621437473448573732415448217598798979894 Sequence: HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK Prediction: +--------++-+-+--------------------+-++-++------------------ Confidence: 434154531452726214767884451357232124163234686866665244225733 Sequence: LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV Prediction: ------------+--+--+----------------------+--++-------------- Confidence: 895836242636442442453114333238697882363535213332443377599889 Sequence: EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA Prediction: ---------------------------+++++---- Confidence: 757763521615366879882775535334452223 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>P38432|COIL Sequence: MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY Prediction: ++--++-+-+----++++-++++++-+-----++-+----------+-----++------ Confidence: 554475362714215566478756526000425627111411440253242475441122 Sequence: LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE Prediction: ---------------------+-+--------------------------++--+----- Confidence: 000000331421110333334635321112000000000010010013136544630011 Sequence: ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA Prediction: -----------------------------------++--+++-++--------------- Confidence: 000000000100000000000000000000103425524656357223323321021133 Sequence: KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS Prediction: --++++++++++++-+--+++++++-------------+--+-+--------+------- Confidence: 348777985676764624666576533413132031315436252231422352121001 Sequence: KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF Prediction: ----------------------+------+-+-+------+-----+------------- Confidence: 000000000000000101012251213136272634331363242354222022011111 Sequence: SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ Prediction: ------------------------------------------------------------ Confidence: 312122010000001100010000000000000000000000000000000000000000 Sequence: TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG Prediction: ----------------------+++++-++-++++++----+++++++++++++++++++ Confidence: 000100001000000001132456865455368865614335789999899989999997 Sequence: HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK Prediction: ++++-+---------------------------------------------+-------+ Confidence: 888545244311230000000000000000000000000000010001123513420015 Sequence: LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV Prediction: ------------------------------------------------------------ Confidence: 000010131120121200011213110200000000000000000000000000000000 Sequence: EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA Prediction: --------------------+---------------- Confidence: 0000000010000001000050000211212111010 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY Prediction: ---+----------------------------++-+--++----------++++++---- Confidence: 332511020203011100000000000000014414223300000223214574342200 Sequence: LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE Prediction: ---------------+-----+-+------------------+++++++++++++----- Confidence: 000000000102000401332723010031000000002322566448437853522010 Sequence: ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA Prediction: -----+++++++++++++++++--------++-+-+++++++++++++++-------+-- Confidence: 133324565989899999865432112022443435445587977594641020211431 Sequence: KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS Prediction: +++++++++++++++++++++--+-++++-++++++++++++++--+++++++++--+-- Confidence: 856998999999888944535224046462556587758955553364546844533431 Sequence: KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF Prediction: ----------------------+-----+-++++++-+---------+++--------+- Confidence: 201322322000100000013241212253464554142122122123531120002233 Sequence: SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ Prediction: ++++++++-----------------------------------------+++----+--- Confidence: 444545442332232102030001000000100000000001001333254432134211 Sequence: TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG Prediction: -+-++++++--++++++-++----------++++++++++++++++++++++++++++++ Confidence: 133575556335754652332232111013449578947695868589999999999996 Sequence: HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK Prediction: ++++++-++++-+++------+-------------------------------------- Confidence: 965763344353745222223410112200220001101010100000000000000000 Sequence: LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV Prediction: ------------------+----------------------------------------- Confidence: 000000120010000001412001220000100000000001000002010300200000 Sequence: EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA Prediction: -----------------------------++----- Confidence: 000000002010201000000000021133421112 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.