| Detail-Interactions: | |
| RAID ID: | RPI00000052 |
|---|---|
| RNA/Protein Symbol 1: | TERC(telomerase RNA) |
| RNA/Protein Category 1: | lncRNA |
| RNA/Protein Symbol 2: | HNRNPC(hnRNPs C1) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | Immunoprecipitation, UV Cross-linking Assay |
| Tissue: | |
| PMID: | 11074006 |
| Detail description: | The binding site for hnRNPs C1 and C2 maps to a 6-base uridylate tract located directly 5` to the template region in the human telomerase RNA (TR) and a 4-base uridylate tract directly 3` to the template in the mouse TR. |
| The Predicated Binding Sites between TERC and HNRNPC | |||||
| By miRanda | Structure | Match Score | Energy Score | TERC Location | HNRNPC Location |
| The Predicated Binding Sites between TERC and HNRNPC | ||||
| By RIsearch | Structure | TERC Location | HNRNPC Location | Score |
| The Predicated Binding Sites of HNRNPC | |
| RBPBD | RRMx1 |
| RsiteDB | |
| BindN |
>sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4 Sequence: MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNE Prediction: ---+-++++++++++++-------+---++-----------+-------+---------- Confidence: 772544686769757579655394644854257267422266464427468786953834 Sequence: RNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSS Prediction: ++-+--------+---------------+-++-+++-+++--------+-+-+-++--+- Confidence: 544954533355677676987968775373792967388536252625434252653452 Sequence: SFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQR Prediction: ---------+----+-+++--+--------+---++++++++++++++++++++++++++ Confidence: 256753763642236556524953232356864467998969898999799978899799 Sequence: GSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSS Prediction: +++++++-+-------+---++-------------+-++-+++-----++-+++++++++ Confidence: 999998928355526652465572228627975954656264523424652666466677 Sequence: SVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSA Prediction: +-++--++-+------------------------+------------+--------+--- Confidence: 728822765554335344436678798687634456564868827654473332555323 Sequence: NGEDDS Prediction: +-+--- Confidence: 534452 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4 Sequence: MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNE Prediction: -----------++---+-+-++--+---------------------+--+++-+-+---- Confidence: 442464422245322367464865559977899588852275351661194547836946 Sequence: RNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSS Prediction: --------------------+-+-++--+++++++++++++-----+-+++++--+---+ Confidence: 488598986837366743754451432144886887577442221241444351142324 Sequence: SFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQR Prediction: -+-------+-+++++++++-+-+++++--+-+-++++++-+++++++-++++--++-++ Confidence: 233321222424536455642523334512743163785636557588247431365245 Sequence: GSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSS Prediction: -+++----+--------------------------------------------------- Confidence: 244813123543416735561296349777884983537744589876557236664424 Sequence: SVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSA Prediction: ------+----------------------------------------+--------+--- Confidence: 375684337457799879889889988887625655888979828663557453446113 Sequence: NGEDDS Prediction: ------ Confidence: 165331 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>P07910|HNRNPC Sequence: MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNE Prediction: ---+-+++++++++++++++++++-+-----------++++++---+-++++++-+---- Confidence: 002816768756667685766757263133110330358568513273997977461120 Sequence: RNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSS Prediction: ---------------+-+------+--+++++++++++++++++++++++---------- Confidence: 220101111131434548434342542566577788787857678766663122222211 Sequence: SFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQR Prediction: --------+-------++++++++++++++++-++-++++++++++++++++-------- Confidence: 111032225244232365667877988886964784888877686778666624442243 Sequence: GSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSS Prediction: +----+--+----+----------++--++--+--------------------------- Confidence: 533246206333374214401322661256125021113232334112210100000000 Sequence: SVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSA Prediction: ------------------------------------------------------------ Confidence: 000000000000000100000000000000000000000000000000000000000000 Sequence: NGEDDS Prediction: ------- Confidence: 1010100 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNE Prediction: +-++-+++-++++-+-+---++--+-------------+-----++++++++-+-+++++ Confidence: 425634462658537260125532533000100101103101204655883535044455 Sequence: RNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSS Prediction: ++++--+-----+-------------++++++++++++++-------------------- Confidence: 954423301011300001000020113434486967646411103100011101010010 Sequence: SFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQR Prediction: -------------------+-++-+-----+--+++++++++++++++-+++++++++++ Confidence: 000200100002200022140343332221402443333657696568364655685557 Sequence: GSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSS Prediction: +++++++-+-+-++----------++------------------------------+-++ Confidence: 556664635342341121000102430000001000000130211010211201124243 Sequence: SVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSA Prediction: ++-+---+-+-------------------------------------------------- Confidence: 452410351411000200100000000000000110000000000001002101223210 Sequence: NGEDDS Prediction: +---+- Confidence: 321242 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.