| Detail-Interactions: | |
| RAID ID: | RPI00000047 |
|---|---|
| RNA/Protein Symbol 1: | BCYRN1P2(BCYRN1P2) |
| RNA/Protein Category 1: | lncRNA |
| RNA/Protein Symbol 2: | FMR1(FMRP) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | |
| Tissue: | |
| PMID: | 19239885 |
| Detail description: | The neural phenotype of BC1 (BCYRN1P2) is consistent with its known interaction with both FMRP, the product of the fragile X mental retardation gene (FMR1), and with mRNAs regulated by FMRP. |
| The Predicated Binding Sites between BCYRN1P2 and FMR1 | |||||
| By miRanda | Structure | Match Score | Energy Score | BCYRN1P2 Location | FMR1 Location |
| The Predicated Binding Sites between BCYRN1P2 and FMR1 | ||||
| By RIsearch | Structure | BCYRN1P2 Location | FMR1 Location | Score |
| The Predicated Binding Sites of FMR1 | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|Q06787|FMR1_HUMAN Fragile X mental retardation protein 1 OS=Homo sapiens GN=FMR1 PE=1 SV=1 Sequence: MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN Prediction: --------+-++----+---+------------------+-------+------+-+--- Confidence: 999999696566344258794696784836676333434539565694763345534464 Sequence: ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP Prediction: ---------+---+----------+--+-------------+--------+-++-+-+++ Confidence: 458653722832254668789929546687949986985375244882856776262896 Sequence: ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR Prediction: +++----+---------+----+-------+-------------------------++++ Confidence: 577324249267955885486853652243627555626223344468989594256577 Sequence: AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN Prediction: ---------++-+++-+---+----+++++++++--++-----------------++--+ Confidence: 636899967654955653675432466646658623578664899399877887555437 Sequence: IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN Prediction: -++-++-+------------------------++-++------------+----+---+- Confidence: 457576344737778778362638278735445558458799999959573775674463 Sequence: GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE Prediction: -+------------+-+-------------------+-++++++-+++-+--++------ Confidence: 466847998433448767344262264588787672537776793466252355363524 Sequence: NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH Prediction: -+++-++-++++-++----------++++++-+---------------+----------- Confidence: 354637827788558666722752265774535844879889785225536393899856 Sequence: LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG Prediction: ----------+--+-------+--+-+++++++++++++++-+---+-++++++++++++ Confidence: 864947953677276494558524537798999988968546435552559699999999 Sequence: HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG Prediction: +++++++++++++++-++-+++++--+----------++--+----++++++++++++++ Confidence: 979989798967874366466776325555477465355435433688987999998898 Sequence: QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS Prediction: +++++++++++-++++++++++++++++++-++++++---+----+-++-++++-+++++ Confidence: 998959776582745789799999779879297864853776432558637787387687 Sequence: EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP Prediction: ++++++++++++++++++-+------------ Confidence: 88895989989999878425436335683785 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|Q06787|FMR1_HUMAN Fragile X mental retardation protein 1 OS=Homo sapiens GN=FMR1 PE=1 SV=1 Sequence: MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN Prediction: --------+-+++---+---+--------------++--+---+---+------------ Confidence: 789989587437611243474375385848885224323527342158342245462674 Sequence: ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP Prediction: --------++-+---+------+-+-++----------------------+-++++-+++ Confidence: 547762613833633424243255813713537875887661546592816675452653 Sequence: ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR Prediction: --+++--+---------+--------+---++------------------------+-++ Confidence: 413432449244733675697946454133655645627225525568999462355268 Sequence: AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN Prediction: -+-------+--+-+-----+-----------+----------------------+++++ Confidence: 545756437627413532443231334373247246458897989475345742257558 Sequence: IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN Prediction: +++-++-++-----------------------+--+-------------+----+-++++ Confidence: 476554443216787988578817187546435136227879998879744552424486 Sequence: GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE Prediction: ++--+------+--+-+------------------------------------------- Confidence: 473745682424357644446141155387468883353214217585737832477778 Sequence: NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH Prediction: ------------------------------------------------+----------- Confidence: 877452343212733778954887876766786876568985365224425296779973 Sequence: LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG Prediction: ----------+--+------------+++++++++++-+-+-+-----+-++++++++++ Confidence: 752726954677547576658154234496576864617134435412416347467797 Sequence: HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG Prediction: ++++++++-+---------------+-----------------+++++++++++++++++ Confidence: 889968541421235452836351742531243157456441254478576999999999 Sequence: QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS Prediction: ++++++++++++++-++++++++++-+--+-------------------------+--++ Confidence: 999999997674753574447755545534532455278938875492164321732244 Sequence: EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP Prediction: ++++-++++-+++++++-----------+--+ Confidence: 44582844729757645241224315534144 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>Q06787|FMR1 Sequence: MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN Prediction: ----------++--++-------------------------------------------- Confidence: 000000113258446542001000010010000001200000101304121210000000 Sequence: ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP Prediction: -------------+-++++++++-++-++-----------------------+-++++++ Confidence: 001000102212262887898784873553320110101111120000123384898887 Sequence: ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR Prediction: ---+----------------------------+-------------------------++ Confidence: 224510210000021101020000012431325121320311122312300112022266 Sequence: AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN Prediction: ---------++---------+--------------------------+--+--+++++++ Confidence: 121001020761112031125312001100013000101101021135326426788999 Sequence: IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN Prediction: +++-++--+--+----------+--------------------------++--+++++++ Confidence: 898365238216231113223373334123313201000000000001056327857899 Sequence: GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE Prediction: +++-++--++++--+-+---+----------------------+---------------- Confidence: 997497225557246151125223223210001001311121151100000000000011 Sequence: NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH Prediction: --------------------------------------------+-+++-++-+------ Confidence: 100111212332111000001000000002000000000001246465645735130234 Sequence: LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG Prediction: --+-------------------+++++++++++++++-------------++++++++++ Confidence: 036231011111231311224455665676568775522121102122336678589999 Sequence: HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG Prediction: ++++++++++++---------------------------------+--+-++++++++++ Confidence: 988898688756444022010110020000011211100002013534545888699999 Sequence: QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS Prediction: ++++++++++----------------------------------------+--+++++++ Confidence: 988999888634310112122200000012021000001000112112135147555778 Sequence: EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP Prediction: +++++++++-++----------------+++-- Confidence: 578855656455332311430133243186740 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN Prediction: --------+--++--------------------------++------+---+-------- Confidence: 000010015235523220300100000000000000001541120004010302321000 Sequence: ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP Prediction: -----+-+-+---+-++-----+---------------------------+---++++++ Confidence: 000003141402342683010050000020000000000132000000023233665864 Sequence: ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR Prediction: ------------------------+-+++-++--+---------------------+--- Confidence: 122113120200330213003020435433750233022201000000001100223103 Sequence: AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN Prediction: --------------------+----------++--------------------+++++++ Confidence: 003023231311323011026210122223144101000000000000000024477355 Sequence: IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN Prediction: +++-+--+-+--------------+---+++----+-+-----------+++--++++++ Confidence: 354241042302010000100030501144433203040200000000043322634675 Sequence: GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE Prediction: -+-------+++--+-++++++++++-----------------+-+++------------ Confidence: 370022201334108295745668732100000000230200241445313022201000 Sequence: NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH Prediction: +--+-++++++---+---------+--++-++---+----------+-+--+-------- Confidence: 312415445653023120111113533553631103101010001240400300000012 Sequence: LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG Prediction: ------------------------+++++++++++++++-+-+-+-+-++++++++++++ Confidence: 000000000030021002300201547899999997845363433343457689999999 Sequence: HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG Prediction: ++++++++++++----------------------------++++++++++++++++++++ Confidence: 999998985434011012213100011020000210330255459899999999999999 Sequence: QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS Prediction: +++++++++++++++++++++++++++++++++-+-+-+-+------++---++-+++++ Confidence: 999999999968745646569989889879573252423140312324422354133446 Sequence: EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP Prediction: ++++++++++++++++++-+-+---------- Confidence: 66696999989455446434341130010011 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.