| Detail-Interactions: | |
| RAID ID: | RPI00000033 |
|---|---|
| RNA/Protein Symbol 1: | Six3OS |
| RNA/Protein Category 1: | lncRNA |
| RNA/Protein Symbol 2: | EYA3(Eya3) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | RNA RNP Immunoprecipitation |
| Tissue: | |
| PMID: | 21936910 |
| Detail description: | Ezh2 and Eya1/3/4 directly bind Six3OS. |
| The Predicated Binding Sites between Six3OS and EYA3 | |||||
| By miRanda | Structure | Match Score | Energy Score | Six3OS Location | EYA3 Location |
| The Predicated Binding Sites between Six3OS and EYA3 | ||||
| By RIsearch | Structure | Six3OS Location | EYA3 Location | Score |
| The Predicated Binding Sites of EYA3 | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|Q99504|EYA3_HUMAN Eyes absent homolog 3 OS=Homo sapiens GN=EYA3 PE=1 SV=3 Sequence: MEEEQDLPEQPVKKAKMQESGEQTISQVSNPDVSDQKPETSSLASNLPMSEEIMTCTDYI Prediction: ------------++-+-+++------+------+--++++++--++------------+- Confidence: 889968855426873835444322524733345532745775445565647778383655 Sequence: PRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQTLQQTQPYAVYPQATQTYGLPPF Prediction: -+++++++++-++-+-+----------+-+++++++++-++---+--+-+-++-+----- Confidence: 386876665626736445378284822457458666554442245575444452456467 Sequence: GALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTSST Prediction: ----------+---++++++-++----+++-+++++++-++----+-++++-+--+++++ Confidence: 788444425353345657563444726564367774873452234636765263565655 Sequence: IANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQSE Prediction: ----------+-+-+-+--+----+--+---+-+++---+++++++--+++---++++++ Confidence: 562856656664524252243554433523343566222756568722556223668675 Sequence: KPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNRGKRKADATSSQDS Prediction: +-+--------++-++++++++++++++++++++++++++++++++++++++++++++-+ Confidence: 624646453345656767688878467676675787669898999998999786775427 Sequence: ELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDL Prediction: ---+-------------------++-+++-+-------+--------------------- Confidence: 285598989999899997589237738972844268844472887999999855989899 Sequence: EECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYR Prediction: --------------------------+---+++++++++-++---+------+----+++ Confidence: 989759496586245242452333525223658669888277435444674852545746 Sequence: KVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVL Prediction: +-+------+++-+---++++++--++-+---------------+-------++------ Confidence: 476253522555552437556642255867477895944842786487552276227287 Sequence: ITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRD Prediction: -----------+----------------+-++--+-----+---+--++-++------+- Confidence: 923247838995989399979889848354583363257447827348575599743667 Sequence: EEIAAKQHNMPFWRITNHGDLVSLHQALELDFL Prediction: -------------+------------------- Confidence: 536472432456649465546839769989999 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|Q99504|EYA3_HUMAN Eyes absent homolog 3 OS=Homo sapiens GN=EYA3 PE=1 SV=3 Sequence: MEEEQDLPEQPVKKAKMQESGEQTISQVSNPDVSDQKPETSSLASNLPMSEEIMTCTDYI Prediction: ------------+--+-------------------------------------------- Confidence: 468858954424425446648867997866464577277344865586767588661514 Sequence: PRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQTLQQTQPYAVYPQATQTYGLPPF Prediction: -++++--------++++-+---------------------------------+------- Confidence: 344453253163234441535141321362442311236256586762843233247253 Sequence: GALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTSST Prediction: -----------------+++++------+--------+--+--------+-----+++-- Confidence: 464467766546544126543435534232322113133342335262132216534312 Sequence: IANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQSE Prediction: ------------++--++-++-----+-------------+-------------+----- Confidence: 522533214423433343233563624136523211114132222253642344322343 Sequence: KPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNRGKRKADATSSQDS Prediction: --+--------+--++----++----+-+--+----++++++++++++++++--++---- Confidence: 123254241335144433213322227141242221344755578877787513442342 Sequence: ELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDL Prediction: ---------------------------+--+----------------------------- Confidence: 685277866988898997678112131413433346712251865789787663767489 Sequence: EECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYR Prediction: ---------------+-------------------++++--+---++++++-++--++++ Confidence: 889738295253133411242243632324121224363334114656345374223848 Sequence: KVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVL Prediction: +-+--+-+++++-+---+++++----------------------+-------+-+--+-- Confidence: 546123233656542316445612112817698895842754893776663251527476 Sequence: ITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRD Prediction: -------------------------+--+--+--+-+---+---+--++--+-------- Confidence: 814236836782778267655668344244242362427545628137754573623315 Sequence: EEIAAKQHNMPFWRITNHGDLVSLHQALELDFL Prediction: -----+-+++---+---+--------------- Confidence: 432555146312244113548738449959868 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>Q99504|EYA3 Sequence: MEEEQDLPEQPVKKAKMQESGEQTISQVSNPDVSDQKPETSSLASNLPMSEEIMTCTDYI Prediction: ------------------------------------------------------------ Confidence: 000000000000010100000000000000000000000000000000000000000000 Sequence: PRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQTLQQTQPYAVYPQATQTYGLPPF Prediction: ------------------------------------------------------------ Confidence: 010000000000000000100000000000000000000000000000000010200100 Sequence: GALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTSST Prediction: ------------------------------------------------------------ Confidence: 000000000000001000000000000000000000000000000000000000000000 Sequence: IANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQSE Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: KPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNRGKRKADATSSQDS Prediction: ------------------------------------------+++++++++++------- Confidence: 000000000000000000000000000000000001123314688688676553242313 Sequence: ELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDL Prediction: -------------------------------------+---------------------- Confidence: 111401010000000004201122323112412321273344000000000000000000 Sequence: EECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYR Prediction: ---------------------------------------------+----+-----++++ Confidence: 000000000000000000000000000000000000000000121734245133446867 Sequence: KVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVL Prediction: +-----------------------------------------------------+--+-- Confidence: 814413123224112002113100000000000000041021000000001011522743 Sequence: ITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRD Prediction: ++++++-++--+-------------+-+-+++-++-++--++-++-+++--+--++++++ Confidence: 566795477305010110311120252645763671862495268457723822667765 Sequence: EEIAAKQHNMPFWRITNHGDLVSLHQALELDFL Prediction: ++---++-++++++-+--------+--------- Confidence: 7543466366757846443402415410100000 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint | |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.