| Detail-Interactions: | |
| RAID ID: | RPI00000032 |
|---|---|
| RNA/Protein Symbol 1: | Six3OS |
| RNA/Protein Category 1: | lncRNA |
| RNA/Protein Symbol 2: | EYA1(Eya1) |
| RNA/Protein Category 2: | Protein |
| Validated Method: | RNA RNP Immunoprecipitation |
| Tissue: | |
| PMID: | 21936910 |
| Detail description: | Ezh2 and Eya1/3/4 directly bind Six3OS. |
| The Predicated Binding Sites between Six3OS and EYA1 | |||||
| By miRanda | Structure | Match Score | Energy Score | Six3OS Location | EYA1 Location |
| The Predicated Binding Sites between Six3OS and EYA1 | ||||
| By RIsearch | Structure | Six3OS Location | EYA1 Location | Score |
| The Predicated Binding Sites of EYA1 | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|Q99502|EYA1_HUMAN Eyes absent homolog 1 OS=Homo sapiens GN=EYA1 PE=1 SV=2 Sequence: MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS Prediction: ------++++++-++++++++-++-++++-++++-+++-++-++-+-+++++-+++--++ Confidence: 999658644769256777888259257673666627552664752627667826773246 Sequence: LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ Prediction: --+-+-++--+++++++-+++----+-+++++-+------+++++---+-++--++---+ Confidence: 435554643377858782654423545746782642663257667242645524654425 Sequence: ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY Prediction: -+-+-++-++-+-+--+-+---------+-++++++++-++----+-++-++++-++--+ Confidence: 465645535535252452556725472252448777862662342435526655257326 Sequence: SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM Prediction: -++-+-++-++++--++-+++-+++++++++++++--+----+-++-++-+++-++--+- Confidence: 254252562667723772657266675588865772253223546636426652653345 Sequence: TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD Prediction: +++++++++++++-++--+--++--+++--+--+--+++-++++++-+++++++-+++++ Confidence: 756788888688736626436452465655454552556476567658667779278698 Sequence: GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL Prediction: +++++++++++++++--++---+-------------------++-+++-++++++-+--- Confidence: 999999999999877234637559898999989999757923782897296575657347 Sequence: RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL Prediction: +------------------------------+-------+++---+-------++----- Confidence: 598699979985598989998975949647252422235555254556524446653477 Sequence: ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT Prediction: ----+------+----+-++-+--+--++-+------+-++--+---------------- Confidence: 624583356485254572666435522552554464264673657592967679485592 Sequence: LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER Prediction: ---+-------++-----------------+----------------+-++--+------ Confidence: 897498244327423828792324784899598939999988984835458336325762 Sequence: IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL Prediction: ---+--+---+----------+--++------+------------------- Confidence: 8944569288599996776754337535457656332467799889989849 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|Q99502|EYA1_HUMAN Eyes absent homolog 1 OS=Homo sapiens GN=EYA1 PE=1 SV=2 Sequence: MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS Prediction: -------------------+--++--+-+--------+----+----------------- Confidence: 579569234454874536231234434253221343131134332153253367544542 Sequence: LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ Prediction: ----------------+-++-----------+-+-------+------------------ Confidence: 243538668862233551562424526323232523673313332465363344354757 Sequence: ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY Prediction: -----------+------+-----------------+--++------------------+ Confidence: 537466353223322612436438587765752221421442444353242222421114 Sequence: SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM Prediction: ----+-----------------++-+----++-----+-------+--------+----- Confidence: 221443214423226432122434333212562222342334331331112222325115 Sequence: TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD Prediction: +--------------------------+------------+--++--------+-++-+- Confidence: 321123422331231227573212211634463453124152143243572344345242 Sequence: GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL Prediction: ++++++++++++--+---------------------------++-+++-+------+--- Confidence: 687979789764114351239728895798879898657821332363353323365225 Sequence: RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL Prediction: +------------------------------+--+--------------+---++-+--- Confidence: 486478978766485748988974839524233332224223365332342223425448 Sequence: ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT Prediction: ----++++++-++--+++++-+--+-+++++-----++-++--+---------------- Confidence: 413476743547422383864512414464552241541581254491878889574284 Sequence: LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER Prediction: -----------+-+--+---------------------------+--+--+--+-+---+ Confidence: 598198475324252747681523773678278827767567944424424236242664 Sequence: IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL Prediction: ---+--++--+----------+--+-+++---+--++--------------- Confidence: 4627147756474623345434456144323244135458658349959858 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>Q99502|EYA1 Sequence: MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS Prediction: ------------------------------------------------------------ Confidence: 000000000001000000000000000000000000000100000000000000000000 Sequence: LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ Prediction: ------------------------------------------------------------ Confidence: 000000000000000010000000000000000000000000000000000000000000 Sequence: ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY Prediction: ------------------------------------------------------------ Confidence: 000000001001010010000000000000000000000000000000000000000000 Sequence: SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000001000000010011211300000 Sequence: TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD Prediction: ----------------------------------------------------------+- Confidence: 000000000000000000000000000000000000000000001000000001244454 Sequence: GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL Prediction: +++++++-++-+----------------------------------------+---+--- Confidence: 576768835525244341211010001000000000420123332411112354437433 Sequence: RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL Prediction: ------------------------------------------------------------ Confidence: 400100000000000000000000000000000000000000000000000000000010 Sequence: ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT Prediction: -+--++--++-----+++++-++------+------------------------------ Confidence: 254185436623444786871651224415200100220420000000000000002113 Sequence: LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER Prediction: ----------------+---+-++--++----------------+-+++++-++-++--+ Confidence: 101200000010241172225469426610300000030122037276676467276238 Sequence: IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL Prediction: +-++-+++--+--++++++++---++-++++++-+---+--+-+--------- Confidence: 52683567238126667657532476366757846343502516410100010 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS Prediction: --------------++-+++-+-+--+++-+---+-+----------------------- Confidence: 000321101212003425553333213452322241331000100000010110000000 Sequence: LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ Prediction: ----------------+----------+---+---------------------------- Confidence: 000000000000031143022100000500230301001100010000101000210002 Sequence: ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY Prediction: ------------------------------------------------------------ Confidence: 000000000000000100310000112220010103111221100200000002000000 Sequence: SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM Prediction: -----------------------+------------------------------------ Confidence: 201011110001000000023124222200010010130000000000010000000100 Sequence: TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD Prediction: ------------------------------------------+---------++++++++ Confidence: 000000000100100000002100100000000000000100321203021336688999 Sequence: GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL Prediction: ++++++++++++++++-------------------------+++--++------------ Confidence: 999999899979686312000000000000000000000013530065221100002102 Sequence: RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL Prediction: -------------------------------++++------------------------- Confidence: 000000000000200000000000000001145462231100010012130110121102 Sequence: ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT Prediction: ----++++-+-++++++-++-+--+++++++++++----++------------------- Confidence: 121359753714755550760421538647797651201452011003000000000000 Sequence: LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER Prediction: -----------+++--+------------------------------------------- Confidence: 000000000035532150000010002000000000000000000002003123222003 Sequence: IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL Prediction: ---+--++--+---+-++--------------+--+---------------- Confidence: 0004227721421243341121003221131151233010000000000000 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.