| Detail-Interactions: | |
| RAID ID: | RPI00000019 |
|---|---|
| RNA/Protein Symbol 1: | CDKN2B-AS1(ANRIL) |
| RNA/Protein Category 1: | lncRNA |
| RNA/Protein Symbol 2: | E2F1 |
| RNA/Protein Category 2: | Protein |
| Validated Method: | Luciferase Reporter Assay |
| Tissue: | HeLa cells, A549 cells |
| PMID: | 20664976 |
| Detail description: | ANRIL is implicated in the regulation of nucleus and potential transcriptional target of E2F1. |
| The Predicated Binding Sites between CDKN2B-AS1 and E2F1 | |||||
| By miRanda | Structure | Match Score | Energy Score | CDKN2B-AS1 Location | E2F1 Location |
| The Predicated Binding Sites between CDKN2B-AS1 and E2F1 | ||||
| By RIsearch | Structure | CDKN2B-AS1 Location | E2F1 Location | Score |
| The Predicated Binding Sites of E2F1 | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|Q01094|E2F1_HUMAN Transcription factor E2F1 OS=Homo sapiens GN=E2F1 PE=1 SV=1 Sequence: MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD Prediction: -------------------------+----------------+-++-++-+--------- Confidence: 898755232225548979887546877744436798467354645635725442443366 Sequence: PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK Prediction: ---------+-++++++-+++---+++-+++---+--------+++++++++++++++-+ Confidence: 689998923626957873596233966277643342645266347678989698679629 Sequence: SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI Prediction: +++++++++++-+-+++-----------------------+-++++-------------- Confidence: 997899876663525442764893548677999759869675666672595799799574 Sequence: AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS Prediction: -+++++---------+-----+----+---+--------------------+-----+++ Confidence: 577775262364232542333962244347537253455987996962226664342655 Sequence: QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE Prediction: ++--+------+-------------+--------------------++++-+-------- Confidence: 574568364586367549769989946435238246422345262575853587989989 Sequence: ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS Prediction: ------+++++++++-++---++-++-----+-++++++++-+++-++------------ Confidence: 926543877976886456232574652326552548877863775244257387765662 Sequence: RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG Prediction: +--+-+------+----------------------------------------------- Confidence: 633748427448582487796378468288646998898938465557897899886647 Sequence: IRDLFDCDFGDLTPLDF Prediction: -+--------------- Confidence: 94899999996945978 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|Q01094|E2F1_HUMAN Transcription factor E2F1 OS=Homo sapiens GN=E2F1 PE=1 SV=1 Sequence: MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD Prediction: ------------------------------------------------------------ Confidence: 465555221212515868898638949968758899378476273542331323534463 Sequence: PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK Prediction: -----------++-+---------+++++++-----------------+-++-+------ Confidence: 667768743143435224323352545574334573423242432243624413244642 Sequence: SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI Prediction: --+++++++++-----+-------------------------++++-++----------- Confidence: 413455853652234832755996799897977226888622455754476177348386 Sequence: AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS Prediction: -++-+++--+-------------------------------------------------- Confidence: 373179731522533359998796797899767489888996885765669698987734 Sequence: QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE Prediction: --------------------------------------------+-+++----------- Confidence: 313948789583665467667869714135439785633234254664423276978867 Sequence: ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS Prediction: ------------------------------------------------------------ Confidence: 866788575266587757585666326679958544647678357354566798999898 Sequence: RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG Prediction: ------------------------------------------------------------ Confidence: 689988999999599889887677789599998999999726753858586376966544 Sequence: IRDLFDCDFGDLTPLDF Prediction: ----------------- Confidence: 62696697876832335 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| RNAbindR |
>Q01094|E2F1 Sequence: MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD Prediction: -------++-++------------------------------------------------ Confidence: 000203257475332102112220020000210000010000000010001001000000 Sequence: PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK Prediction: -------------------+-+-++++-+++---------+------------------- Confidence: 000000011011114114253525656477632100313464244412421220101201 Sequence: SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI Prediction: ----++++++++++--++-------------+-+---------+++-+--++--++-+-- Confidence: 334357868796674467412102101221151641012112357825435932672733 Sequence: AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS Prediction: -++++++++++--+---------------------------------------------- Confidence: 498789958573251111101010000000000000021011000100110100100001 Sequence: QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE Prediction: --------------------------------------------+-++-+++-------- Confidence: 332210100100112021111121142431240333322231215266366612011010 Sequence: ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000000000 Sequence: RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000001000000000000010 Sequence: IRDLFDCDFGDLTPLDF Prediction: ------------------ Confidence: 100000000000101000 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD Prediction: ------------------------------------------------------------ Confidence: 100011110121000000000000010000000000000000000000000000000000 Sequence: PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK Prediction: -----------+-++++++++++-+-+-+++-+----------+++-+++++++++++++ Confidence: 000000013223346536545541524175503011300010255623666564547468 Sequence: SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI Prediction: ++++++++-+--------------++------------+----+++-++----------- Confidence: 754575832532032032000000442201120200003011246715500100300030 Sequence: AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS Prediction: -++++++++++-++++--+-+---+----------------------------------- Confidence: 069797948662554422424322422000000000020000010010000000002001 Sequence: QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE Prediction: -+--+------++------------+-+---+------+---+-+-+-++---------- Confidence: 340030132204410200000000030310030001013220437363453100000011 Sequence: ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS Prediction: -------+---------------------------------------------------- Confidence: 012012232232010000000000000000000120100000000000000000000000 Sequence: RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000000000000000000000000001010 Sequence: IRDLFDCDFGDLTPLDF Prediction: ---------------+- Confidence: 00000000000000042 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.