The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00000010
RNA/Protein Symbol 1:CDKN2B-AS1(ANRIL)
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: CBX7
RNA/Protein Category 2: Protein
Validated Method:
Tissue:  
PMID: 21874119 
Detail description:

ANRIL was also found to coimmunoprecipitate with CBX7, which is component of the polycomb repressive complex 1 (PRC1). 

The Predicated Binding Sites between CDKN2B-AS1 and CBX7
By miRanda Structure Match Score Energy Score CDKN2B-AS1 Location CBX7 Location
The Predicated Binding Sites between CDKN2B-AS1 and CBX7
By RIsearch Structure CDKN2B-AS1 Location CBX7 Location Score
The Predicated Binding Sites of CBX7
RBPBD
RsiteDB
BindN
>sp|O95931|CBX7_HUMAN Chromobox protein homolog 7 OS=Homo sapiens GN=CBX7 PE=1 SV=1

Sequence:    MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
Prediction:  --------------+-++++-++++--+------++-+++-------------------+
Confidence:  979588877988836497892995772469252455276422667999989499573646

Sequence:    EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA
Prediction:  --+-++++++++++++++-------+-+-+++++++-+-+----------+-+-----+-
Confidence:  237386878999999578456329253558788989263565649353438263235766

Sequence:    GAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAP
Prediction:  -------------------+++++++++-+-++++++++-++-++++-++----------
Confidence:  474478648457428432378599588648368795678358268862763758688685

Sequence:    DVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAA
Prediction:  ------------------------------------+-----------+-+---+-----
Confidence:  798386777646724445676977636234222464522737358363556528568477

Sequence:    EGFFRDRSGKF
Prediction:  ----+-++-+-
Confidence:  35475574373


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|O95931|CBX7_HUMAN Chromobox protein homolog 7 OS=Homo sapiens GN=CBX7 PE=1 SV=1

Sequence:    MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
Prediction:  -------------------+-++++--+--------------------------------
Confidence:  667679999979973624292663556336132336534523778889889798595631

Sequence:    EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA
Prediction:  ----+-++++++++++-+-+-++-+-------+-----------------+---------
Confidence:  322541434858457517143343355582424222623347777674524113327714

Sequence:    GAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAP
Prediction:  -----------------------------+----+--++--+--++-++-----------
Confidence:  277687567545364575512414835594511152245323423713611225463756

Sequence:    DVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAA
Prediction:  --------------------------------------------------+-+-+-----
Confidence:  878386474657777799899877512222346698636868866262245346744378

Sequence:    EGFFRDRSGKF
Prediction:  ------++-+-
Confidence:  35341365451


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>O95931|CBX7
Sequence:    MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
Prediction:  --------------+--++++++++-+++-+++++-------------------------
Confidence:  100100001020047238899999938863887662321321000010000000000001

Sequence:    EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA
Prediction:  ----+-+++++++++++++-++++----------------------------------+-
Confidence:  321162688999998778645555422213211123310230011011012232222253

Sequence:    GAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAP
Prediction:  --------------------------------------+------+---+----------
Confidence:  111100101211311221131121000103143441126004223643453132120210

Sequence:    DVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAA
Prediction:  -----------------------------------------------++-+++-++-+--
Confidence:  001001000000000000000000010023223111011110341227537563862533

Sequence:    EGFFRDRSGKF
Prediction:  +++++-+--+--
Confidence:  658664744710

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
Prediction:  ----------------+-++++++++++--+-+-+--++++------------------+
Confidence:  021020000000002232695777953430426060154540010100000000000004

Sequence:    EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA
Prediction:  ----++++++++++++++---+--+----+++++++++++-+----------+-+-----
Confidence:  000255889989857745020320311137558643554434120101003342311010

Sequence:    GAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAP
Prediction:  ---------------+++-+++++++++++-++++--+++++---+--+-----------
Confidence:  000000000000100333165465578548335542255444122310410000001000

Sequence:    DVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAA
Prediction:  ------------------------------------------------------------
Confidence:  100000000000000000000000000100000000000000010000002110100100

Sequence:    EGFFRDRSGKF
Prediction:  -++------+-
Confidence:  14501223243

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.