| Detail-Interactions: | |
| RAID ID: | RPI00000006 |
|---|---|
| RNA/Protein Symbol 1: | CBR3-AS1(PlncRNA-1) |
| RNA/Protein Category 1: | lncRNA |
| RNA/Protein Symbol 2: | AR |
| RNA/Protein Category 2: | Protein |
| Validated Method: | Luciferase Reporter Assay, Western Blot |
| Tissue: | LNCaP, LNCaP-AI, PC3, and C4-2 |
| PMID: | 22264502 |
| Detail description: | The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor. |
| The Predicated Binding Sites between CBR3-AS1 and AR | |||||
| By miRanda | Structure | Match Score | Energy Score | CBR3-AS1 Location | AR Location |
| The Predicated Binding Sites between CBR3-AS1 and AR | ||||
| By RIsearch | Structure | CBR3-AS1 Location | AR Location | Score |
| The Predicated Binding Sites of AR | |
| RBPBD | |
| RsiteDB | |
| BindN |
>sp|P10275|ANDR_HUMAN Androgen receptor OS=Homo sapiens GN=AR PE=1 SV=2 Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ Prediction: --------+-+-++++++++----------+--------+-++--+--++--+------- Confidence: 989586549462977997792564486559558832222825544643544456777332 Sequence: QQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSA Prediction: +++++++++++++++++++++++++++++-+--++++++++++-+-------+-++-+-- Confidence: 567777777777776666777798877652532768579867845798886342662525 Sequence: LECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLK Prediction: ------+------------++--------------+--+-+-----------++-+---- Confidence: 634245554645666344468343237452454654545256246652433545254582 Sequence: DILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKA Prediction: ------+----------------+++++++--++++++++-++---+++-++--+---+- Confidence: 586347424255244334642228997959237568898825822365736437557356 Sequence: VSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKS Prediction: -+-----------------+-+----+----------+-+--------+------+--++ Confidence: 848267878788779344244854564979978424784436646747462676453287 Sequence: TEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSR Prediction: +--+--+---++-+++--+--+-+-+-+++-+++++----++-+--+----------+++ Confidence: 622653522486275823554444352755257847326345555253587556462558 Sequence: DYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGP Prediction: -------------+++++++++-+----------+-------+-++----+------+++ Confidence: 322586987642255554444548728635762457275555558442555735533557 Sequence: GSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPY Prediction: ++++++++-+++------------+----++++++++++++++++++++++-+------+ Confidence: 696869652875323894756627453435556777777777777777665255345526 Sequence: GYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLE Prediction: -+++--+---------------------++--+-+-+--+---------++-++---+-- Confidence: 276822534354424747559537554659436252536633664465255356334742 Sequence: TARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRND Prediction: +-+-------------+---------+---+---+--+-+----+--++++++---+++- Confidence: 557758869843664442677678676453555652256645835545474563245654 Sequence: CTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLT Prediction: -+--+-+++++++-+-++------+---++-++--+-+-------+++++++++++-+-- Confidence: 264273977868929575634655632388487335557365433679777775652742 Sequence: VSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK Prediction: ------------------------------+++--------------------------- Confidence: 732956368469898999998799845423555342576882284246636874993692 Sequence: ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRM Prediction: -----+----------------------------++--++-------------+-++++- Confidence: 743666475988899896555989998889422467525767289999996736468683 Sequence: YSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDR Prediction: +++--+-+---------------------------------+--------+--------+ Confidence: 686276653735779494938788989599999699883346432766795764927985 Sequence: IIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIIS Prediction: ----+++++++++++-++------------+----------------------------- Confidence: 775479898996787354853886393478669459599899343672989879998992 Sequence: VQVPKILSGKVKPIYFHTQ Prediction: ----+--+-+-+------- Confidence: 8394664646762527444 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| BindN+ |
>sp|P10275|ANDR_HUMAN Androgen receptor OS=Homo sapiens GN=AR PE=1 SV=2 |
| RNAbindR |
>P10275|AR Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ Prediction: --------+---+------++--------------------------------------- Confidence: 030414248332732242165112300120000000110211001112421440211111 Sequence: QQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSA Prediction: ------------------------------------------------------------ Confidence: 222002000000000000000023211100002213132322112000000010113301 Sequence: LECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLK Prediction: ------------------------------------------------------------ Confidence: 200110133021001114123111110000001000000000100010000010000000 Sequence: DILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKA Prediction: ------------------------------------------------------------ Confidence: 000000000100010000000001311300100100000100110002200000210021 Sequence: VSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKS Prediction: ------------------------------------------------------------ Confidence: 000200100000010000000010000100000000000020010000000000000000 Sequence: TEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSR Prediction: ------------------------------------------------------------ Confidence: 000000110010000000001001112100000000000000000000000000000001 Sequence: DYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGP Prediction: ------------------------------------------------------------ Confidence: 000000000000000000000000000000000010000000001000000000000000 Sequence: GSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPY Prediction: ------------------------------------------------------------ Confidence: 000101001000000000000000001111101210110213323423331111000132 Sequence: GYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLE Prediction: ------------------------------------------------------------ Confidence: 110010100100000003100310000101111110132100000000000100000000 Sequence: TARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRND Prediction: --------------------------++----------------+----+--+-+++++- Confidence: 000000000000000010100112115624242442442211126222454474556754 Sequence: CTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLT Prediction: ----+-+++++++++++++-++-++++++++++-++-+---------------------- Confidence: 323473766887688588636545799899698379162010000000000000000000 Sequence: VSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK Prediction: ----------------------------+--+------+----------+------++-+ Confidence: 001100220100002001000100032253253111025001313420373024438647 Sequence: ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRM Prediction: ++++++------------------------+++------+-------------------- Confidence: 676667422012000002111011002433765343142711430230001024122421 Sequence: YSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDR Prediction: --------------------------------------++--++------+-++-++--+ Confidence: 322223144001110323022103112301100311137644572013115276275036 Sequence: IIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIIS Prediction: --+---++++++++++++--+--------------------------------------- Confidence: 116424576797898667137011100000110010201010011001022222012111 Sequence: VQVPKILSGKVKPIYFHTQ Prediction: -------+++-++-+++++- Confidence: 22024225751883568780 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest). |
| Pprint |
Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ Prediction: -+--+---+-+-+---+-------------------++++-------------------- Confidence: 232352325352723040123011200200000023653632202101323330000011 Sequence: QQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSA Prediction: -----------------+++++++++++++++++++-+++-+--+-----------++-- Confidence: 222233333322223234444455444445556754374434224000000001024413 Sequence: LECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLK Prediction: --+--------------------------------------------------------- Confidence: 123200200000010000121100000100200000000000000000000002201000 Sequence: DILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKA Prediction: ----------------------++++++-++-++++++---------------------- Confidence: 000000000301000000032345455926434645442100100231301220200120 Sequence: VSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKS Prediction: ----++-------------------------------------------------+---+ Confidence: 010133100000000002101102311000000310000001000000000000131034 Sequence: TEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSR Prediction: ----------+-+--+-------+-+---------------------------------- Confidence: 200000011252531522122134241331111211000000000001000000000000 Sequence: DYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGP Prediction: -----------------------+-+------+--------------------------- Confidence: 000000000001221333120224140212114300022010102212122220002012 Sequence: GSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPY Prediction: -----------------------------------+---------++------------- Confidence: 100110000000000200000000000000100024000000003353221200210010 Sequence: GYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLE Prediction: -----+------------------------------------------------------ Confidence: 000135221000022123120102232123212122000000020002032302132212 Sequence: TARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRND Prediction: -+---------+---------+-+++-++++++--++-++++++++++++++++++++++ Confidence: 231101020215220200100416542999768004529999789499978996998979 Sequence: CTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLT Prediction: +++++++++++++++++++++++++++++++++++++++++++++++--+---------- Confidence: 877999999999879699959999997699699559978864444443341210101210 Sequence: VSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK Prediction: -------------------------------------------------------+++-- Confidence: 222111101121111000000000020112222100000000001200000002045502 Sequence: ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRM Prediction: +--+--------------------------++---------------------+------ Confidence: 401510000000000001011000000000541130100000000000000034200000 Sequence: YSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDR Prediction: --------+--+-----+-------------------++--------------------- Confidence: 020000034224012204020000000000000000173010000000000000000000 Sequence: IIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIIS Prediction: ----+++++++++++-++--------+--------------------------------- Confidence: 000156655554456134010000005000000000000000000000100000000000 Sequence: VQVPKILSGKVKPIYFHTQ Prediction: --+-++-+-+-++-+++-+ Confidence: 0030842327054344533 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.