The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00000003
RNA/Protein Symbol 1:RN7SL1(7SL RNA)
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: APOBEC3G(A3G)
RNA/Protein Category 2: Protein
Validated Method: Immunoprecipitation, qRT-PCR
Tissue: 293 cells, 293/A3G-HA cells, 293T cells 
PMID: 17881443 
Detail description:

We demonstrate here that A3G selectively interacts with certain polymerase III (Pol III)-derived RNAs, including Y3 and 7SL RNAs. 

The Predicated Binding Sites between RN7SL1 and APOBEC3G
By miRanda Structure Match Score Energy Score RN7SL1 Location APOBEC3G Location
The Predicated Binding Sites between RN7SL1 and APOBEC3G
By RIsearch Structure RN7SL1 Location APOBEC3G Location Score
The Predicated Binding Sites of APOBEC3G
RBPBD
RsiteDB
BindN
>sp|Q9HC16|ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G OS=Homo sapiens GN=APOBEC3G PE=1 SV=1

Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
Prediction:  -----+------+---+++++++---------+-++--+------+---++--++--+--
Confidence:  894794796388554565577564478584347555725723383582856246822524

Sequence:    ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
Prediction:  +---+---------+++++++-+-------------------------------------
Confidence:  656276672234226689878263692978999899989949666677274344757226

Sequence:    ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
Prediction:  --+--+--------------------------------------+---------------
Confidence:  754835987996628663453688997928823722622443446228278789589732

Sequence:    YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
Prediction:  -++++-+--------------+++++++-+--+----------------++---------
Confidence:  675682573888897945622476778827334457539627899646655373685975

Sequence:    FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
Prediction:  -----------------------------++++++-+---------+-------------
Confidence:  783374826989899976986668772545568762732927667662333333333333

Sequence:    KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
Prediction:  ------------------------------------------------------------
Confidence:  333333333333333333333333333333333333333333333333333333333333

Sequence:    WDGLDEHSQDLSGRLRAILQNQEN
Prediction:  ------------------------
Confidence:  333333333333333333333333


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|Q9HC16|ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G OS=Homo sapiens GN=APOBEC3G PE=1 SV=1

Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
Prediction:  ++++-++--++------------------+-----------++-++-----+--+-+---
Confidence:  463637514363337555526226224124145176557425326542448365434313

Sequence:    ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
Prediction:  ------------------------------+---------------------+-+-----
Confidence:  431435474694282551344455631823362124222462796877545377464727

Sequence:    ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
Prediction:  -+-----------------------+---+------------------------------
Confidence:  656446475411227244621223255144435746334544453455756345235545

Sequence:    YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
Prediction:  -------------+----------+-----+---++-++------+-+---------++-
Confidence:  438696859425832343333434472174421234445652483416122321431642

Sequence:    FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
Prediction:  +-+++--------------------------------+----------------------
Confidence:  323534355366734238269797695865467436637242531232325748956351

Sequence:    KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
Prediction:  ---+--------+----------------+------------------------------
Confidence:  121571857377473775435232624573547282433735454555454644532336

Sequence:    WDGLDEHSQDLSGRLRAILQNQEN
Prediction:  -------------+------+--+
Confidence:  258656432453358245833115


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>Q9HC16|APOBEC3G
Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
Prediction:  -+++-++------------+-++--++++++++++-++-+++++-++----+----+---
Confidence:  257825722331222023454574477788957874672777772561234511426124

Sequence:    ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
Prediction:  -+++-------------------------++-+++++++------+----+++-+++++-
Confidence:  356523201002200003112411121035848999858402210613438883979764

Sequence:    ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
Prediction:  ++--+-+-++++---++-+----+-+-+-+--+----------------+----------
Confidence:  794474545576434662543446482647326442111011230032153233434231

Sequence:    YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
Prediction:  ------------------------+-++-++++++++++++++-+++++--+---+----
Confidence:  312011040001100001211333625645565889889665517657623611363242

Sequence:    FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
Prediction:  --------------+++++-+-------------------++-+++++++----------
Confidence:  201121341442346555615112113023124431220358479898674113003134

Sequence:    KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
Prediction:  -+++-++++++++-+------++-+-+-+--+---+--+-+--------+--+--+-++-
Confidence:  388829796666945434233662546454261445337353212131252254254554

Sequence:    WDGLDEHSQDLSGRLRAILQNQEN
Prediction:  ------+------+------+--+-
Confidence:  3442226223321711220464360

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
Prediction:  --++-+++--+------------------+++++-----++-+++++--------++-++
Confidence:  135615430140000010000300210009444313310561664532230000335345

Sequence:    ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
Prediction:  ++-------+-+-----+---+-+--+------+-+--+------------+--+-----
Confidence:  952100000404000223112538004000010424303001000000030320400000

Sequence:    ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
Prediction:  -+-----------+-++++++++-++-+-+------------------------------
Confidence:  031110001100233343454473463415001000000000000020000000000000

Sequence:    YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
Prediction:  --------------+-----------+-------+++++--+--------------+++-
Confidence:  000000010020136200000021004312102297565303103302222232225443

Sequence:    FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
Prediction:  +++++------++-------------------+-+--+------+---------------
Confidence:  543342331323312321000000000211334260150000113211020000001023

Sequence:    KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
Prediction:  +-++-+------+--------+--++--+-------------------------------
Confidence:  635426000000402000102431343152032203000000000001000002000020

Sequence:    WDGLDEHSQDLSGRLRAILQNQEN
Prediction:  +------------+-----+++-+
Confidence:  400000000000130222047524

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.