The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00000002
RNA/Protein Symbol 1:RN7SL1(7SL RNA)
RNA/Protein Category 1: lncRNA
RNA/Protein Symbol 2: APOBEC3F
RNA/Protein Category 2: Protein
Validated Method: Immunoblotting, Immunoprecipitation, qRT-PCR
Tissue:  
PMID: 18067920 
Detail description:

Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging. 

The Predicated Binding Sites between RN7SL1 and APOBEC3F
By miRanda Structure Match Score Energy Score RN7SL1 Location APOBEC3F Location
The Predicated Binding Sites between RN7SL1 and APOBEC3F
By RIsearch Structure RN7SL1 Location APOBEC3F Location Score
The Predicated Binding Sites of APOBEC3F
RBPBD
RsiteDB
BindN
>sp|Q8IUX4|ABC3F_HUMAN DNA dC->dU-editing enzyme APOBEC-3F OS=Homo sapiens GN=APOBEC3F PE=1 SV=3

Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
Prediction:  -+---+----+--+----++---+---+++---------+++++++++---+--+-+-++
Confidence:  654366227374253252556345234566225497468679889958442564836556

Sequence:    QPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAA
Prediction:  +----------------------------------------------------+---+--
Confidence:  545459889998799854636328859569955667757893996899887375825455

Sequence:    RLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFL
Prediction:  +------+--++---+-++---+-+-----------------------------------
Confidence:  772234563277425675632487587999989599978934473557666578764869

Sequence:    HRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRN
Prediction:  ----++--+------------------++++-+---------------+-----+---+-
Confidence:  323854786676577486993978326885728342398979787274524232836472

Sequence:    QVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLT
Prediction:  -----------+--------------+-+-----------------------+--+----
Confidence:  264453363775879679999972325253535233233655687899586964246463

Sequence:    IFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYN
Prediction:  ----+-------------++-++---+---------+-----------------+--+--
Confidence:  762769549685732344753442455835563366539786994787545263645436

Sequence:    FLFLDSKLQEILE
Prediction:  -------------
Confidence:  8879642956999


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).


BindN+
>sp|Q8IUX4|ABC3F_HUMAN DNA dC->dU-editing enzyme APOBEC-3F OS=Homo sapiens GN=APOBEC3F PE=1 SV=3

Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
Prediction:  ++++-++---+------------------+-----------++-++-+------+-+---
Confidence:  463637514153327444416226224124145176567324426424436165425313

Sequence:    QPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAA
Prediction:  ---------------------------------------------------+-+------
Confidence:  343437477797487863346649419332731242435867977776453665746165

Sequence:    RLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFL
Prediction:  +---------+-------+-+-+-+-----------------------------------
Confidence:  653343635131364353513657442494535465555333372222423656642547

Sequence:    HRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRN
Prediction:  ----------------------+--+--+++-++--+--------+--+---------+-
Confidence:  342821681455465694672757247154424431665556532513423234152442

Sequence:    QVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLT
Prediction:  ------+--------------------------+--+---------------+--+----
Confidence:  144541532624779869999757643552724353324242576896744332257184

Sequence:    IFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYN
Prediction:  ----+-----------------+-------------------------------------
Confidence:  727748667775622215145543472825247253445545736457222351287565

Sequence:    FLFLDSKLQEILE
Prediction:  -------------
Confidence:  6888853934795


*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).

RNAbindR
>Q8IUX4|APOBEC3F
Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
Prediction:  -+++-++------------+--+--+++++++++++++-+++++-++-+--+----+---
Confidence:  378928843431232022453463378789968875663886784672533622335124

Sequence:    QPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAA
Prediction:  +-++-----------------------+++++++++++-----------+++-+++++++
Confidence:  545533404101210042123312331558689998783013014134378839797758

Sequence:    RLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFL
Prediction:  ++++-++--+++--++-+--+---+--+-------------+------------------
Confidence:  955736544765435635316233623734311101124115424412322323241113

Sequence:    HRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRN
Prediction:  --+-------------+---+++-++--++++++++++----+-+++-++--+++-----
Confidence:  226232210130221364146673674468799988863410535663563256632011

Sequence:    QVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLT
Prediction:  -----++-------------------------++-+++++++-----------+++-+++
Confidence:  301347844441410110100101222111035847889867411300212437882969

Sequence:    IFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYN
Prediction:  ++-++--+-----++---++-++-+---+--+-------------------++------+
Confidence:  764794472333365433564551623352364421110111411433444553432116

Sequence:    FLFLDSKLQEILE
Prediction:  ------+-----+-
Confidence:  22331171122150

*** Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
*** Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Pprint
Sequence:    MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
Prediction:  --++-++---+------------------++++------++-+++++-------++++++
Confidence:  135615430140000010000300320219644322210531766543220210447465

Sequence:    QPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAA
Prediction:  ++----------------+---+--+------+-+-------------+-+--+------
Confidence:  953120000000000000421040170010203132020000001011414305000000

Sequence:    RLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFL
Prediction:  +----------+++++-++-+++-+-----------------------------------
Confidence:  311100012004444637624440400000000000000002000000000000000000

Sequence:    HRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRN
Prediction:  --+---------------------+--+--+-+++++--+---+-++--++++++++-+-
Confidence:  013000000200020000010010332330429546532300230543266353555032

Sequence:    QVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLT
Prediction:  --++-+------------------+-+--+------+---------------+-+--+--
Confidence:  224434112000000000000022335004000000313202001000101141430500

Sequence:    IFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYN
Prediction:  -----------------+---+------+------------------------+------
Confidence:  000031100001100223332630322040110000000000000000000003000000

Sequence:    FLFLDSKLQEILE
Prediction:  -------------
Confidence:  0000002000002

***Prediction:  binding residues are labeled with '+' and in red;
                 non-binding residues labeled with '-' and in green.
***Confidence:  from level 0 (lowest) to level 9 (highest).
                 
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.