ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-302a

MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000683 hsa-miR-302a-5p	ACUUAAACGUGGAUGUACUUGCU
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000683 hsa-miR-302a-5p	ACUUAAACGUGGAUGUACUUGCU
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000683 hsa-miR-302a-5p	ACUUAAACGUGGAUGUACUUGCU
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000683 hsa-miR-302a-5p	ACUUAAACGUGGAUGUACUUGCU
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000683 hsa-miR-302a-5p	ACUUAAACGUGGAUGUACUUGCU
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA
MI0000738	MIPF0000071	CCACCACUUAAACGUGGAUGUACUUGCUUUGAAACUAAAGAAGUAAGUGCUUCCAUGUUUUGGUGAUGG	MIMAT0000684 hsa-miR-302a-3p	UAAGUGCUUCCAUGUUUUGGUGA

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

CDK4,AKT1,BMPR2,NR2F2,ABCA1,CCND1,TAC1,TOB2,TP63,DAZAP2,CDKN1A,CCL5,TP53,LEFTY2,SLAIN1
more » CDK4,AKT1,BMPR2,NR2F2,ABCA1,CCND1,TAC1,TOB2,TP63,DAZAP2,CDKN1A,CCL5,TP53,LEFTY2,SLAIN1,LEFTY1

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa05214	Glioma	CCND1,CDK4,CDKN1A,AKT1,TP53,	2.57E-6
hsa05218	Melanoma	CCND1,CDK4,CDKN1A,AKT1,TP53,	4.17E-6
hsa05220	Chronic myeloid leukemia	CCND1,CDK4,CDKN1A,AKT1,TP53,	5.20E-6
hsa05219	Bladder cancer	CCND1,CDK4,CDKN1A,TP53,	4.25E-5
hsa05223	Non-small cell lung cancer	CCND1,CDK4,AKT1,TP53,	9.09E-5

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0008361	regulation of cell size	TP63,CDK4,LEFTY1,CDKN1A,AKT1,LEFTY2,TP53,	3.14E-8
GO:0032535	regulation of cellular component size	TP63,CDK4,LEFTY1,CDKN1A,AKT1,LEFTY2,TP53,	1.60E-7
GO:0042127	regulation of cell proliferation	CCND1,BMPR2,TOB2,TAC1,TP63,CDK4,CDKN1A,TP53,	5.25E-6
GO:0000082	G1/S transition of mitotic cell cycle	CCND1,CDK4,CDKN1A,AKT1,	2.36E-5
GO:0009411	response to UV	CCND1,CDKN1A,AKT1,TP53,	2.77E-5

GO:0045596	negative regulation of cell differentiation	CCND1,TOB2,ABCA1,TP63,TP53,	5.58E-5
GO:0009991	response to extracellular stimulus	CCND1,BMPR2,CDKN1A,AKT1,TP53,	5.99E-5
GO:0010604	positive regulation of macromolecule metabolic process	CCND1,BMPR2,NR2F2,TP63,CDK4,AKT1,TP53,	1.22E-4
GO:0045792	negative regulation of cell size	TP63,CDKN1A,AKT1,TP53,	1.30E-4
GO:0051329	interphase of mitotic cell cycle	CCND1,CDK4,CDKN1A,AKT1,	1.46E-4
GO:0051325	interphase	CCND1,CDK4,CDKN1A,AKT1,	1.59E-4
GO:0007166	cell surface receptor linked signal transduction	CCND1,BMPR2,CCL5,TAC1,ABCA1,TP63,LEFTY1,AKT1,LEFTY2,	1.71E-4
GO:0051726	regulation of cell cycle	CCND1,CDK4,CDKN1A,AKT1,TP53,	2.90E-4
GO:0009416	response to light stimulus	CCND1,CDKN1A,AKT1,TP53,	3.48E-4
GO:0009725	response to hormone stimulus	CCND1,CCL5,TAC1,CDKN1A,AKT1,	4.29E-4
GO:0009628	response to abiotic stimulus	CCND1,TAC1,CDKN1A,AKT1,TP53,	4.34E-4
GO:0031328	positive regulation of cellular biosynthetic process	NR2F2,ABCA1,TP63,CDK4,AKT1,TP53,	4.47E-4
GO:0009891	positive regulation of biosynthetic process	NR2F2,ABCA1,TP63,CDK4,AKT1,TP53,	4.78E-4
GO:0048145	regulation of fibroblast proliferation	CDK4,CDKN1A,TP53,	5.80E-4
GO:0009719	response to endogenous stimulus	CCND1,CCL5,TAC1,CDKN1A,AKT1,	6.24E-4
GO:0008284	positive regulation of cell proliferation	CCND1,TAC1,TP63,CDK4,CDKN1A,	6.78E-4
GO:0001558	regulation of cell growth	TP63,CDKN1A,AKT1,TP53,	9.40E-4
GO:0031667	response to nutrient levels	CCND1,BMPR2,AKT1,TP53,	9.83E-4
GO:0009314	response to radiation	CCND1,CDKN1A,AKT1,TP53,	1.02E-2
GO:0042493	response to drug	CCND1,CCL5,CDKN1A,TP53,	1.28E-2
GO:0000079	regulation of cyclin-dependent protein kinase activity	CCND1,CDKN1A,AKT1,	1.38E-2
GO:0008629	induction of apoptosis by intracellular signals	TP63,CDKN1A,TP53,	1.38E-2
GO:0032270	positive regulation of cellular protein metabolic process	CCND1,BMPR2,CDK4,AKT1,	1.59E-2
GO:0051247	positive regulation of protein metabolic process	CCND1,BMPR2,CDK4,AKT1,	1.79E-2
GO:0051240	positive regulation of multicellular organismal process	BMPR2,CCL5,TAC1,AKT1,	1.82E-2
GO:0031668	cellular response to extracellular stimulus	BMPR2,CDKN1A,TP53,	1.93E-2
GO:0022402	cell cycle process	CCND1,CDK4,CDKN1A,AKT1,TP53,	2.15E-2
GO:0033554	cellular response to stress	CCND1,BMPR2,TP63,CDKN1A,TP53,	2.16E-2
GO:0003006	reproductive developmental process	CCND1,TP63,AKT1,LEFTY2,	2.23E-2
GO:0007389	pattern specification process	BMPR2,NR2F2,TP63,LEFTY2,	2.35E-2
GO:0051094	positive regulation of developmental process	BMPR2,CCL5,TOB2,AKT1,	2.64E-2
GO:0051384	response to glucocorticoid stimulus	CCND1,CCL5,CDKN1A,	2.85E-2
GO:0042770	DNA damage response, signal transduction	CCND1,TP63,TP53,	3.00E-2
GO:0070141	response to UV-A	CCND1,AKT1,	3.10E-2
GO:0031960	response to corticosteroid stimulus	CCND1,CCL5,CDKN1A,	3.38E-2
GO:0051173	positive regulation of nitrogen compound metabolic process	NR2F2,ABCA1,TP63,AKT1,TP53,	3.47E-2
GO:0010557	positive regulation of macromolecule biosynthetic process	NR2F2,TP63,CDK4,AKT1,TP53,	3.67E-2
GO:0030308	negative regulation of cell growth	TP63,CDKN1A,TP53,	3.94E-2
GO:0040008	regulation of growth	TP63,CDKN1A,AKT1,TP53,	4.70E-2
GO:0007167	enzyme linked receptor protein signaling pathway	BMPR2,LEFTY1,AKT1,LEFTY2,	4.73E-2
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	BMPR2,LEFTY1,LEFTY2,	4.92E-2
GO:0002347	response to tumor cell	TP63,TP53,	5.16E-2
GO:0010033	response to organic substance	CCND1,CCL5,TAC1,CDKN1A,AKT1,	5.21E-2
GO:0043066	negative regulation of apoptosis	TP63,CDKN1A,AKT1,TP53,	5.21E-2
GO:0045892	negative regulation of transcription, DNA-dependent	ARID4A,NR2F2,TP63,TP53,	5.30E-2
GO:0043069	negative regulation of programmed cell death	TP63,CDKN1A,AKT1,TP53,	5.42E-2
GO:0060548	negative regulation of cell death	TP63,CDKN1A,AKT1,TP53,	5.46E-2
GO:0051253	negative regulation of RNA metabolic process	ARID4A,NR2F2,TP63,TP53,	5.55E-2
GO:0007568	aging	CCL5,TP63,TP53,	5.59E-2
GO:0045926	negative regulation of growth	TP63,CDKN1A,TP53,	5.59E-2
GO:0000278	mitotic cell cycle	CCND1,CDK4,CDKN1A,AKT1,	5.90E-2
GO:0042592	homeostatic process	CCL5,TAC1,ABCA1,AKT1,TP53,	6.02E-2
GO:0006974	response to DNA damage stimulus	CCND1,TP63,CDKN1A,TP53,	6.03E-2
GO:0014070	response to organic cyclic substance	CCND1,TAC1,CDKN1A,	6.73E-2
GO:0007049	cell cycle	CCND1,CDK4,CDKN1A,AKT1,TP53,	6.77E-2
GO:0022403	cell cycle phase	CCND1,CDK4,CDKN1A,AKT1,	8.05E-2
GO:0045737	positive regulation of cyclin-dependent protein kinase activity	CCND1,AKT1,	8.25E-2
GO:0030857	negative regulation of epithelial cell differentiation	CCND1,TP63,	8.25E-2
GO:0043065	positive regulation of apoptosis	TP63,CDKN1A,AKT1,TP53,	8.93E-2
GO:0043068	positive regulation of programmed cell death	TP63,CDKN1A,AKT1,TP53,	9.11E-2
GO:0010942	positive regulation of cell death	TP63,CDKN1A,AKT1,TP53,	9.22E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value