ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-29

MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045
MI0000087	MIPF0000009	AUGACUGAUUUCUUUUGGUGUUCAGAGUCAAUAUAAUUUUCUAGCACCAUCUGAAAUCGGUUAU	MIMAT0000086 hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	miR-29a was previously know as miR-29 here and in . The maturesequence shown here represents the most commonly cloned form fromlarge-scale cloning studies .
MI0000107	MIPF0000009	CUUCUGGAAGCUGGUUUCACAUGGUGGCUUAGAUUUUUCCAUCUUUGUAUCUAGCACCAUUUGAAAUCAGUGUUUUAGGAG	MIMAT0000100 hsa-miR-29b-3p	UAGCACCAUUUGAAAUCAGUGUU	This sequence was named mir-102-1 in reference . Human miR-102 is ahomologue of mouse miR-29b (MIR:MI0000143) and so has been renamed herefor consistency.
MI0000735	MIPF0000009	AUCUCUUACACAGGCUGACCGAUUUCUCCUGGUGUUCAGAGUCUGUUUUUGUCUAGCACCAUUUGAAAUCGGUUAUGAUGUAGGGGGA	MIMAT0000681 hsa-miR-29c-3p	UAGCACCAUUUGAAAUCGGUUA	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
	MIPF0001858		MIMAT00045

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

ZBTB10,FGG,SKI,TFAP2C,CYTB,C15orf52,PPM1D,FAM133A,SFPQ,HMGA2,PLAG1,CD276,BACE1,EZH2,HUWE1
more » ZBTB10,FGG,SKI,TFAP2C,CYTB,C15orf52,PPM1D,FAM133A,SFPQ,HMGA2,PLAG1,CD276,BACE1,EZH2,HUWE1,NID1,ZC3H18,PIK3R1,ITIH5,VEGFA,NUMB,IRGQ,MYCN,ESR1,BCAP31,SUV420H2,IFNG,VDAC1,MORF4L1,COL5A3,NKIRAS2,DDX21,COL7A1,DKK1,FBN1,IMPDH1,IGF1,USP22,BMP1,ELN,MYC,MMP2,MMP15,CDV3,ADAMTS7,COL4A1,HDAC4,ABL1,NAV3,PDGFC,SH3GLB1,TRIM68,PAN2,CCT4,CDC42,DNMT3B,TIMM44,U2SURP,NNT,C1QTNF6,MEG3,FAM105B,LRP10,PSMA2,MRPS35,PDHX,BCL11A,CHIC2,SP1,KDM5B,FAM102B,IGFBP1,TMTC3,RSL24D1,KIAA1671,HMGCR,NCOA3,TDG,RNF19A,HNRNPM,CALU,FAM126B,DHX40,PXDN,AKT3,TPT1,EIF3E,PDGFB,RAN,R3HDM4,COL4A3BP,TET1,GNB4,ZNF45,SARS,KIAA0895,NUS1,SPIN4,S100B,COL4A2,CTC1,UROS,ADAM12,TPD52L2,MKI67,PTER,ADO,COL4A4,FAM123B,DNMT3A,PPP1R13B,MMS19,CCNT2,TCL1A,C14orf43,BCKDHA,FREM2,DICER1,MKL2,PIGN,BCL2,HP1BP3,WNT4,KCTD15,BACH2,EIF2C1,FAM59B,RET,OAZ1,XK,TXNDC16,COL1A2,ITGA11,KIAA1549,GAPDH,COL21A1,RPS4X,CCDC14,RAB30,DUSP2,ZFP91,C9orf140,CTNNBIP1,MMP24,DNAJB11,SCAF8,GLUL,COL4A3,CDK13,FGA,TP53,RRAGC,OIP5,PPT1,C1orf96,DAG1,LPL,CPEB4,CDC42SE1,SPARC,SRSF10,PRKAA1,TBX21,CCND2,MTHFD2,CECR2,IFIH1,COL1A1,VDAC2,SMARCC1,PURG,B4GALT5,FAM109B,HBP1,FOS,NOB1,HHAT,SLC16A1,SFRP2,CIT,SERPINB9,SOWAHC,COL4A5,C12orf76,CDK6,MCL1,PPP1R14C,TRIM63,JUN,PDPN,IRF2BP2,RPS6KA3,ANKRD13C,ADAMTS9,CLDN1,TIPRL,BCL7A,TNFAIP3,GNB2L1,KLHL28,FGB,C5orf13,DCAF12,BFAR,TRPC5,STK19,LAMC1,SYNCRIP,CEP68,CPEB3,PRKAB2,DNMT1,WBSCR16,COL15A1,WSB2,COL3A1,RUNDC3B,SCAF11,YY1,CRKL,CDC23,PTEN,HDGF,GRN,TGFB3,RAX,DIABLO,SP2,KREMEN2,NASP

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa04510	Focal adhesion	JUN,PTEN,COL3A1,BCL2,COL4A1,PDGFB,COL4A2,COL4A4,PDGFC,IGF1,CRKL,AKT3,VEGFA,LAMC1,COL5A3,COL1A1,CCND2,COL1A2,ITGA11,PIK3R1,CDC42,	3.10E-11
hsa05200	Pathways in cancer	JUN,MMP2,PTEN,BCL2,COL4A1,PDGFB,COL4A2,COL4A4,IGF1,ABL1,TP53,CDK6,RET,CRKL,AKT3,VEGFA,LAMC1,WNT4,FOS,PIK3R1,CDC42,MYC,TGFB3,	5.98E-9
hsa05222	Small cell lung cancer	CDK6,PTEN,BCL2,AKT3,COL4A1,COL4A2,LAMC1,COL4A4,PIK3R1,TP53,MYC,	8.01E-7
hsa04512	ECM-receptor interaction	COL3A1,COL4A1,COL4A2,LAMC1,COL5A3,COL4A4,COL1A1,COL1A2,ITGA11,DAG1,	7.21E-6
hsa05211	Renal cell carcinoma	JUN,CRKL,AKT3,VEGFA,PDGFB,PIK3R1,CDC42,TGFB3,	1.25E-4

hsa05218	Melanoma	CDK6,PTEN,AKT3,PDGFB,PDGFC,IGF1,PIK3R1,TP53,	1.36E-4
hsa05220	Chronic myeloid leukemia	CDK6,CRKL,AKT3,ABL1,PIK3R1,TP53,MYC,TGFB3,	1.93E-4
hsa05210	Colorectal cancer	JUN,BCL2,AKT3,FOS,PIK3R1,TP53,MYC,TGFB3,	3.93E-4
hsa05214	Glioma	CDK6,PTEN,AKT3,PDGFB,IGF1,PIK3R1,TP53,	5.09E-4
hsa05215	Prostate cancer	PTEN,BCL2,AKT3,PDGFB,PDGFC,IGF1,PIK3R1,TP53,	5.60E-4
hsa04722	Neurotrophin signaling pathway	JUN,RPS6KA3,CRKL,BCL2,AKT3,ABL1,PIK3R1,CDC42,TP53,	8.50E-4
hsa05212	Pancreatic cancer	CDK6,AKT3,VEGFA,PIK3R1,CDC42,TP53,TGFB3,	1.04E-2
hsa04150	mTOR signaling pathway	RPS6KA3,AKT3,VEGFA,PRKAA1,IGF1,PIK3R1,	1.46E-2
hsa04115	p53 signaling pathway	CDK6,PPM1D,PTEN,CCND2,IGF1,TP53,	4.78E-2
hsa05213	Endometrial cancer	PTEN,AKT3,PIK3R1,TP53,MYC,	9.85E-2
hsa04010	MAPK signaling pathway	JUN,RPS6KA3,DUSP2,CRKL,AKT3,PDGFB,FOS,CDC42,TP53,MYC,TGFB3,	1.09E-1
hsa04310	Wnt signaling pathway	JUN,CTNNBIP1,WNT4,CCND2,DKK1,SFRP2,TP53,MYC,	1.11E-1
hsa05410	Hypertrophic cardiomyopathy (HCM)	PRKAB2,PRKAA1,IGF1,ITGA11,DAG1,TGFB3,	1.21E-1
hsa04012	ErbB signaling pathway	JUN,CRKL,AKT3,ABL1,PIK3R1,MYC,	1.33E-1
hsa04110	Cell cycle	CDK6,CDC23,CCND2,ABL1,TP53,MYC,TGFB3,	1.57E-1
hsa05219	Bladder cancer	MMP2,VEGFA,TP53,MYC,	3.04E-1
hsa04660	T cell receptor signaling pathway	JUN,IFNG,AKT3,FOS,PIK3R1,CDC42,	3.08E-1
hsa04914	Progesterone-mediated oocyte maturation	RPS6KA3,AKT3,CDC23,IGF1,PIK3R1,	5.11E-1
hsa05223	Non-small cell lung cancer	CDK6,AKT3,PIK3R1,TP53,	5.73E-1
hsa05216	Thyroid cancer	RET,TP53,MYC,	8.04E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0008283	cell proliferation	S100B,ELN,PTEN,BCL2,PDGFB,CTNNBIP1,COL4A3,CDV3,NUMB,IGF1,GLUL,COL4A3BP,IMPDH1,TP53,CD276,MORF4L1,PDPN,VEGFA,MKI67,NASP,HDGF,MYC,	4.99E-7
GO:0010604	positive regulation of macromolecule metabolic process	JUN,CDC23,SMARCC1,PDGFC,IGF1,ESR1,DNMT1,NCOA3,CD276,PSMA2,DNMT3B,IFNG,VEGFA,MMS19,USP22,TGFB3,BCL2,MKL2,TBX21,PDGFB,HDAC4,SP1,RAN,TP53,ZFP91,CCND2,FOS,RPS4X,MYC,BCKDHA,	4.65E-6
GO:0008284	positive regulation of cell proliferation	JUN,BCL2,PDGFB,PDGFC,HDAC4,IGF1,CD276,ZFP91,CDK13,CDK6,IFNG,MYCN,VEGFA,LAMC1,GRN,CCND2,RPS4X,MYC,	5.04E-5
GO:0042127	regulation of cell proliferation	JUN,PDGFC,IGF1,SPARC,CD276,CDK13,IFNG,MYCN,VEGFA,TPD52L2,GRN,SKI,TGFB3,PPM1D,PTEN,BCL2,PDGFB,COL4A3,HDAC4,TP53,ZFP91,CDK6,LAMC1,CCND2,RPS4X,MYC,	6.43E-5
GO:0043066	negative regulation of apoptosis	PTEN,BCL2,SH3GLB1,IGF1,ESR1,PPT1,TP53,MCL1,ZFP91,VEGFA,TPT1,TNFAIP3,SERPINB9,BFAR,MYC,TGFB3,	9.99E-5

GO:0051054	positive regulation of DNA metabolic process	JUN,IFNG,TBX21,PDGFB,PDGFC,IGF1,TGFB3,	1.07E-4
GO:0043069	negative regulation of programmed cell death	PTEN,BCL2,SH3GLB1,IGF1,ESR1,PPT1,TP53,MCL1,ZFP91,VEGFA,TPT1,TNFAIP3,SERPINB9,BFAR,MYC,TGFB3,	1.16E-4
GO:0060548	negative regulation of cell death	PTEN,BCL2,SH3GLB1,IGF1,ESR1,PPT1,TP53,MCL1,ZFP91,VEGFA,TPT1,TNFAIP3,SERPINB9,BFAR,MYC,TGFB3,	1.20E-4
GO:0051052	regulation of DNA metabolic process	JUN,IFNG,TBX21,PDGFB,PDGFC,IGF1,TP53,MYC,TGFB3,	1.62E-4
GO:0001944	vasculature development	JUN,COL15A1,PTEN,MMP2,COL3A1,MKL2,CRKL,VEGFA,PDPN,NUS1,DICER1,COL1A1,COL1A2,	1.66E-4
GO:0031399	regulation of protein modification process	JUN,BCL2,PDGFB,CDC23,PDGFC,HDAC4,IGF1,DNMT1,DNMT3B,PSMA2,ZFP91,IFNG,CCND2,TGFB3,	2.00E-4
GO:0031401	positive regulation of protein modification process	ZFP91,IFNG,BCL2,CDC23,HDAC4,CCND2,IGF1,DNMT1,PSMA2,TGFB3,DNMT3B,	2.39E-4
GO:0010033	response to organic substance	JUN,PTEN,COL3A1,BCL2,PDGFB,COL4A3,HDAC4,GNB4,GLUL,ESR1,MCL1,IFNG,IGFBP1,UROS,MMS19,DICER1,COL1A1,CCND2,FOS,PIK3R1,MYC,BCKDHA,TGFB3,	3.20E-4
GO:0032270	positive regulation of cellular protein metabolic process	ZFP91,IFNG,BCL2,CDC23,HDAC4,CCND2,IGF1,RPS4X,DNMT1,PSMA2,TGFB3,DNMT3B,	3.46E-4
GO:0010628	positive regulation of gene expression	JUN,SMARCC1,MKL2,HDAC4,IGF1,ESR1,DNMT1,SP1,NCOA3,RAN,TP53,DNMT3B,IFNG,VEGFA,MMS19,USP22,FOS,MYC,BCKDHA,TGFB3,	3.59E-4
GO:0016568	chromatin modification	EZH2,SMARCC1,HDAC4,DNMT1,SUV420H2,DNMT3A,DNMT3B,MORF4L1,HUWE1,CECR2,USP22,NASP,KDM5B,	3.72E-4
GO:0010810	regulation of cell-substrate adhesion	CDK6,PTEN,BCL2,NID1,COL1A1,PIK3R1,	3.84E-4
GO:0001501	skeletal system development	MMP2,COL3A1,BCL2,BMP1,HDAC4,IGF1,SP1,SPARC,RPS6KA3,COL1A1,COL1A2,MYC,TGFB3,FBN1,	4.20E-4
GO:0051247	positive regulation of protein metabolic process	ZFP91,IFNG,BCL2,CDC23,HDAC4,CCND2,IGF1,RPS4X,DNMT1,PSMA2,TGFB3,DNMT3B,	4.94E-4
GO:0009891	positive regulation of biosynthetic process	JUN,SMARCC1,MKL2,PDGFB,PDGFC,HDAC4,IGF1,NCOA3,SP1,RAN,TP53,CD276,IFNG,VEGFA,MMS19,PRKAA1,USP22,FOS,RPS4X,MYC,BCKDHA,TGFB3,	5.02E-4
GO:0006916	anti-apoptosis	BCL2,VEGFA,TPT1,TNFAIP3,SH3GLB1,SERPINB9,BFAR,IGF1,ESR1,MYC,MCL1,	5.22E-4
GO:0045740	positive regulation of DNA replication	JUN,PDGFB,PDGFC,IGF1,TGFB3,	5.25E-4
GO:0001568	blood vessel development	JUN,COL15A1,COL3A1,PTEN,MMP2,CRKL,VEGFA,MKL2,NUS1,DICER1,COL1A1,COL1A2,	5.28E-4
GO:0030198	extracellular matrix organization	ELN,COL3A1,NID1,COL4A2,LAMC1,COL5A3,COL1A1,COL1A2,	5.37E-4
GO:0006259	DNA metabolic process	PDGFB,IGF1,ABL1,PPT1,DNMT1,RAN,TDG,DNMT3A,TP53,SFPQ,DNMT3B,MORF4L1,CECR2,MMS19,NASP,POLD3,FOS,MYC,	5.46E-4
GO:0010557	positive regulation of macromolecule biosynthetic process	JUN,SMARCC1,MKL2,PDGFB,PDGFC,HDAC4,IGF1,NCOA3,SP1,RAN,TP53,CD276,IFNG,VEGFA,MMS19,USP22,FOS,RPS4X,MYC,BCKDHA,TGFB3,	5.90E-4
GO:0051726	regulation of cell cycle	JUN,PTEN,BCL2,CDC23,IGF1,PPP1R13B,TP53,CDK13,CDK6,USP22,CCND2,CCNT2,MYC,CDC42,	6.04E-4
GO:0006325	chromatin organization	EZH2,SMARCC1,HDAC4,HMGA2,SUV420H2,DNMT1,DNMT3A,DNMT3B,MORF4L1,HUWE1,CECR2,USP22,NASP,KDM5B,HP1BP3,	6.65E-4
GO:0032268	regulation of cellular protein metabolic process	JUN,BCL2,PDGFB,CDC23,EIF2C1,PDGFC,HDAC4,IGF1,DNMT1,DNMT3B,PSMA2,ZFP91,IFNG,CCND2,RPS4X,EIF3E,TGFB3,	7.57E-4
GO:0008637	apoptotic mitochondrial changes	JUN,BCL2,SH3GLB1,TP53,MYC,	7.82E-4
GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	JUN,SMARCC1,MKL2,PDGFB,TBX21,PDGFC,HDAC4,IGF1,NCOA3,SP1,RAN,TP53,IFNG,VEGFA,MMS19,USP22,FOS,MYC,BCKDHA,TGFB3,	8.56E-4
GO:0051276	chromosome organization	EZH2,SMARCC1,CDC23,HDAC4,HMGA2,SUV420H2,DNMT1,DNMT3A,TP53,DNMT3B,MORF4L1,HUWE1,CECR2,USP22,NASP,KDM5B,HP1BP3,	9.65E-4
GO:0001503	ossification	MMP2,BCL2,BMP1,COL1A1,IGF1,SP1,SPARC,TGFB3,	9.78E-4
GO:0006304	DNA modification	FOS,DNMT1,TDG,DNMT3A,DNMT3B,	9.95E-4
GO:0031328	positive regulation of cellular biosynthetic process	JUN,SMARCC1,MKL2,PDGFB,PDGFC,HDAC4,IGF1,NCOA3,SP1,RAN,TP53,CD276,IFNG,VEGFA,MMS19,USP22,FOS,RPS4X,MYC,BCKDHA,TGFB3,	1.04E-2
GO:0051173	positive regulation of nitrogen compound metabolic process	JUN,SMARCC1,MKL2,PDGFB,TBX21,PDGFC,HDAC4,IGF1,NCOA3,SP1,RAN,TP53,IFNG,VEGFA,MMS19,USP22,FOS,MYC,BCKDHA,TGFB3,	1.24E-2
GO:0048145	regulation of fibroblast proliferation	CDK6,PDGFB,PDGFC,IGF1,TP53,	1.24E-2
GO:0007179	transforming growth factor beta receptor signaling pathway	JUN,COL3A1,PDGFB,COL1A2,FOS,TGFB3,	1.31E-2
GO:0042981	regulation of apoptosis	JUN,IFIH1,PTEN,BCL2,COL4A3,SH3GLB1,IGF1,ABL1,ESR1,PPT1,PPP1R13B,TP53,MCL1,ZFP91,DIABLO,IFNG,VEGFA,TPT1,TNFAIP3,SERPINB9,BFAR,MYC,TGFB3,	1.36E-2
GO:0043523	regulation of neuron apoptosis	JUN,ZFP91,BCL2,PPT1,ESR1,TP53,TGFB3,	1.41E-2
GO:0060348	bone development	MMP2,BCL2,BMP1,COL1A1,IGF1,SP1,SPARC,TGFB3,	1.44E-2
GO:0006275	regulation of DNA replication	JUN,PDGFB,PDGFC,IGF1,TP53,TGFB3,	1.52E-2
GO:0043067	regulation of programmed cell death	JUN,IFIH1,PTEN,BCL2,COL4A3,SH3GLB1,IGF1,ABL1,ESR1,PPT1,PPP1R13B,TP53,MCL1,ZFP91,DIABLO,IFNG,VEGFA,TPT1,TNFAIP3,SERPINB9,BFAR,MYC,TGFB3,	1.54E-2
GO:0010941	regulation of cell death	JUN,IFIH1,PTEN,BCL2,COL4A3,SH3GLB1,IGF1,ABL1,ESR1,PPT1,PPP1R13B,TP53,MCL1,ZFP91,DIABLO,IFNG,VEGFA,TPT1,TNFAIP3,SERPINB9,BFAR,MYC,TGFB3,	1.62E-2
GO:0016569	covalent chromatin modification	HUWE1,EZH2,MORF4L1,USP22,HDAC4,SUV420H2,DNMT3A,DNMT3B,	1.66E-2
GO:0035239	tube morphogenesis	RET,BCL2,MYCN,PDPN,VEGFA,DICER1,WNT4,IGF1,	1.74E-2
GO:0042325	regulation of phosphorylation	JUN,PTEN,BCL2,PDGFB,PDGFC,IGF1,PPP1R14C,ZFP91,DUSP2,IFNG,PRKAA1,HMGCR,CCND2,CCNT2,CDC42,TGFB3,	1.76E-2
GO:0001775	cell activation	ZFP91,COL3A1,BCL2,FGB,BCL11A,FGG,HDAC4,PIK3R1,FGA,IMPDH1,TP53,CD276,	1.90E-2
GO:0010035	response to inorganic substance	JUN,PXDN,PTEN,BCL2,UROS,FGB,COL1A1,FGG,FOS,FGA,	1.97E-2
GO:0048008	platelet-derived growth factor receptor signaling pathway	PTEN,VEGFA,PDGFB,PDGFC,	2.04E-2
GO:0045893	positive regulation of transcription, DNA-dependent	JUN,SMARCC1,MKL2,HDAC4,IGF1,SP1,NCOA3,RAN,TP53,IFNG,VEGFA,MMS19,FOS,MYC,TGFB3,BCKDHA,	2.21E-2
GO:0050679	positive regulation of epithelial cell proliferation	VEGFA,LAMC1,GRN,CCND2,IGF1,	2.26E-2
GO:0051254	positive regulation of RNA metabolic process	JUN,SMARCC1,MKL2,HDAC4,IGF1,SP1,NCOA3,RAN,TP53,IFNG,VEGFA,MMS19,FOS,MYC,TGFB3,BCKDHA,	2.39E-2
GO:0043414	biopolymer methylation	EZH2,FOS,SUV420H2,DNMT1,DNMT3A,DNMT3B,	2.45E-2
GO:0051591	response to cAMP	JUN,COL1A1,CCND2,FOS,BCKDHA,	2.47E-2
GO:0001932	regulation of protein amino acid phosphorylation	JUN,ZFP91,IFNG,BCL2,PDGFB,PDGFC,CCND2,IGF1,TGFB3,	2.51E-2
GO:0007167	enzyme linked receptor protein signaling pathway	JUN,PTEN,COL3A1,PDGFB,PDGFC,RET,VEGFA,IGFBP1,FOS,SKI,COL1A2,PIK3R1,TGFB3,	2.51E-2
GO:0051174	regulation of phosphorus metabolic process	JUN,PTEN,BCL2,PDGFB,PDGFC,IGF1,PPP1R14C,ZFP91,DUSP2,IFNG,PRKAA1,HMGCR,CCND2,CCNT2,CDC42,TGFB3,	2.59E-2
GO:0019220	regulation of phosphate metabolic process	JUN,PTEN,BCL2,PDGFB,PDGFC,IGF1,PPP1R14C,ZFP91,DUSP2,IFNG,PRKAA1,HMGCR,CCND2,CCNT2,CDC42,TGFB3,	2.59E-2
GO:0060395	SMAD protein signal transduction	JUN,SKI,FOS,	2.66E-2
GO:0014911	positive regulation of smooth muscle cell migration	BCL2,PDGFB,IGF1,	2.66E-2
GO:0044093	positive regulation of molecular function	BCL2,CDC23,PDGFB,COL4A3,PDGFC,HDAC4,ABL1,NCOA3,TP53,PSMA2,DIABLO,IFNG,PRKAA1,CCND2,SKI,CDC42,MYC,TGFB3,	2.66E-2
GO:0001836	release of cytochrome c from mitochondria	JUN,BCL2,TP53,MYC,	2.74E-2
GO:0050678	regulation of epithelial cell proliferation	CDK6,VEGFA,LAMC1,GRN,CCND2,IGF1,	2.77E-2
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	JUN,COL3A1,PDGFB,COL1A2,SKI,FOS,TGFB3,	2.80E-2
GO:0045596	negative regulation of cell differentiation	EZH2,ZFP91,CDK6,DICER1,WNT4,HDAC4,IGF1,SKI,TCL1A,TP53,	2.80E-2
GO:0035295	tube development	RET,BCL2,MYCN,PDPN,VEGFA,DICER1,WNT4,IGF1,SP1,TGFB3,	3.17E-2
GO:0051130	positive regulation of cellular component organization	ZFP91,NUMB,IGF1,PPT1,DNMT1,PIK3R1,CDC42,TGFB3,DNMT3B,	3.32E-2
GO:0048660	regulation of smooth muscle cell proliferation	JUN,IFNG,VEGFA,PDGFB,IGF1,	3.46E-2
GO:0006915	apoptosis	JUN,RRAGC,PTEN,BCL2,COL4A3,SH3GLB1,VDAC1,PPT1,PPP1R13B,TP53,MCL1,CECR2,DIABLO,IFNG,TNFAIP3,BFAR,MYC,BCAP31,	3.51E-2
GO:0009719	response to endogenous stimulus	PTEN,BCL2,PDGFB,GNB4,ESR1,IGFBP1,MMS19,UROS,COL1A1,CCND2,FOS,PIK3R1,TGFB3,BCKDHA,	3.63E-2
GO:0032259	methylation	EZH2,FOS,SUV420H2,DNMT1,DNMT3A,DNMT3B,	3.73E-2
GO:0040029	regulation of gene expression, epigenetic	DICER1,EIF2C1,FOS,DNMT1,DNMT3A,DNMT3B,	3.95E-2
GO:0030183	B cell differentiation	BCL2,BCL11A,HDAC4,PIK3R1,TP53,	4.04E-2
GO:0006305	DNA alkylation	FOS,DNMT1,DNMT3A,DNMT3B,	4.05E-2
GO:0006306	DNA methylation	FOS,DNMT1,DNMT3A,DNMT3B,	4.05E-2
GO:0012501	programmed cell death	JUN,RRAGC,PTEN,BCL2,COL4A3,SH3GLB1,VDAC1,PPT1,PPP1R13B,TP53,MCL1,CECR2,DIABLO,IFNG,TNFAIP3,BFAR,MYC,BCAP31,	4.07E-2
GO:0006730	one-carbon metabolic process	EZH2,MTHFD2,FOS,SUV420H2,DNMT1,DNMT3A,DNMT3B,	4.24E-2
GO:0045941	positive regulation of transcription	JUN,SMARCC1,MKL2,HDAC4,IGF1,SP1,NCOA3,RAN,TP53,IFNG,VEGFA,MMS19,USP22,FOS,MYC,TGFB3,BCKDHA,	4.39E-2
GO:0034097	response to cytokine stimulus	JUN,COL3A1,BCL2,HDAC4,FOS,MCL1,	4.41E-2
GO:0009725	response to hormone stimulus	PTEN,BCL2,PDGFB,GNB4,ESR1,IGFBP1,MMS19,COL1A1,CCND2,FOS,PIK3R1,TGFB3,BCKDHA,	4.43E-2
GO:0007346	regulation of mitotic cell cycle	CDK13,BCL2,CDC23,USP22,IGF1,CDC42,TP53,MYC,	4.73E-2
GO:0048545	response to steroid hormone stimulus	PTEN,BCL2,PDGFB,COL1A1,CCND2,FOS,ESR1,TGFB3,BCKDHA,	4.76E-2
GO:0051960	regulation of nervous system development	ZFP91,IFNG,BCL2,COL4A4,NUMB,CCND2,IGF1,TP53,DNMT3B,	4.76E-2
GO:0006357	regulation of transcription from RNA polymerase II promoter	JUN,TFAP2C,YY1,SMARCC1,CTNNBIP1,MKL2,HDAC4,IGF1,ABL1,DNMT1,SP1,DNMT3A,TP53,SP2,MYCN,VEGFA,FOS,SKI,MYC,TGFB3,	4.78E-2
GO:0048146	positive regulation of fibroblast proliferation	CDK6,PDGFB,PDGFC,IGF1,	5.11E-2
GO:0001952	regulation of cell-matrix adhesion	CDK6,PTEN,BCL2,PIK3R1,	5.69E-2
GO:0043062	extracellular structure organization	ELN,COL3A1,NID1,COL4A2,LAMC1,COL5A3,COL1A1,COL1A2,	6.88E-2
GO:0043588	skin development	COL3A1,COL5A3,COL1A1,COL1A2,	6.97E-2
GO:0030199	collagen fibril organization	COL3A1,COL5A3,COL1A1,COL1A2,	6.97E-2
GO:0060284	regulation of cell development	ZFP91,BCL2,COL4A4,NUMB,HDAC4,CCND2,TP53,TGFB3,DNMT3B,	7.00E-2
GO:0051301	cell division	CECR2,CDK13,CDK6,OIP5,CDC23,CCND2,HMGA2,CCNT2,CIT,RAN,CDC42,	7.17E-2
GO:0030335	positive regulation of cell migration	BCL2,PDPN,VEGFA,PDGFB,IGF1,PIK3R1,	7.28E-2
GO:0001934	positive regulation of protein amino acid phosphorylation	ZFP91,IFNG,BCL2,CCND2,IGF1,TGFB3,	7.28E-2
GO:0034330	cell junction organization	BCL2,LAMC1,NUMB,CDC42,TGFB3,	7.46E-2
GO:0045449	regulation of transcription	JUN,EZH2,TFAP2C,SMARCC1,ZNF45,BCL11A,IGF1,ESR1,SFPQ,MYCN,MMS19,PLAG1,SKI,BCL7A,TBX21,CTNNBIP1,MKL2,EIF2C1,ABL1,SUV420H2,ZFP91,KDM5B,MYC,ZBTB10,HMGA2,NCOA3,DNMT1,DNMT3A,DNMT3B,IRF2BP2,IFNG,VEGFA,USP22,SRSF10,TGFB3,YY1,C14orf43,HDAC4,RAX,HBP1,SP1,RAN,TP53,SP2,MORF4L1,BACH2,FOS,CCNT2,HDGF,BCKDHA,	8.40E-2
GO:0048661	positive regulation of smooth muscle cell proliferation	JUN,VEGFA,PDGFB,IGF1,	8.41E-2
GO:0051153	regulation of striated muscle cell differentiation	EZH2,BCL2,COL4A4,HDAC4,	9.18E-2
GO:0030168	platelet activation	COL3A1,FGB,FGG,FGA,	9.18E-2
GO:0048534	hemopoietic or lymphoid organ development	CDK6,CRKL,BCL2,VEGFA,BCL11A,HDAC4,SP1,PIK3R1,CDC42,TP53,	9.24E-2
GO:0010812	negative regulation of cell-substrate adhesion	PTEN,COL1A1,PIK3R1,	9.33E-2
GO:0007049	cell cycle	PPM1D,BCL2,CDC23,HBP1,HMGA2,ABL1,RAN,CIT,TP53,PSMA2,CDK6,IFNG,OIP5,PDPN,MKI67,USP22,CCND2,NASP,CCNT2,MYC,	9.39E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value