ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-26a

MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0000082 hsa-miR-26a-5p	UUCAAGUAAUCCAGGAUAGGCU	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000083	MIPF0000043	GUGGCCUCGUUCAAGUAAUCCAGGAUAGGCUGUGCAGGUCCCAAUGGGCCUAUUCUUGGUUACUUGCACGGGGACGC	MIMAT0004499 hsa-miR-26a-1-3p	CCUAUUCUUGGUUACUUGCACG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0004681 hsa-miR-26a-2-3p	CCUAUUCUUGAUUACUUGUUUC	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0000082 hsa-miR-26a-5p	UUCAAGUAAUCCAGGAUAGGCU	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000083	MIPF0000043	GUGGCCUCGUUCAAGUAAUCCAGGAUAGGCUGUGCAGGUCCCAAUGGGCCUAUUCUUGGUUACUUGCACGGGGACGC	MIMAT0004499 hsa-miR-26a-1-3p	CCUAUUCUUGGUUACUUGCACG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0000082 hsa-miR-26a-5p	UUCAAGUAAUCCAGGAUAGGCU	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000083	MIPF0000043	GUGGCCUCGUUCAAGUAAUCCAGGAUAGGCUGUGCAGGUCCCAAUGGGCCUAUUCUUGGUUACUUGCACGGGGACGC	MIMAT0004499 hsa-miR-26a-1-3p	CCUAUUCUUGGUUACUUGCACG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0000082 hsa-miR-26a-5p	UUCAAGUAAUCCAGGAUAGGCU	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000083	MIPF0000043	GUGGCCUCGUUCAAGUAAUCCAGGAUAGGCUGUGCAGGUCCCAAUGGGCCUAUUCUUGGUUACUUGCACGGGGACGC	MIMAT0004499 hsa-miR-26a-1-3p	CCUAUUCUUGGUUACUUGCACG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0000082 hsa-miR-26a-5p	UUCAAGUAAUCCAGGAUAGGCU	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000083	MIPF0000043	GUGGCCUCGUUCAAGUAAUCCAGGAUAGGCUGUGCAGGUCCCAAUGGGCCUAUUCUUGGUUACUUGCACGGGGACGC	MIMAT0004499 hsa-miR-26a-1-3p	CCUAUUCUUGGUUACUUGCACG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000750	MIPF0000043	GGCUGUGGCUGGAUUCAAGUAAUCCAGGAUAGGCUGUUUCCAUCUGUGAGGCCUAUUCUUGAUUACUUGUUUCUGGAGGCAGCU	MIMAT0000082 hsa-miR-26a-5p	UUCAAGUAAUCCAGGAUAGGCU	miR-26a was cloned from HeLa cells . Two predicted hairpin precursorsequences are present on chromosome 3 (MIR:MI0000083) and 12(MIR:MI0000750), each with homologues in mouse (MIR:MI0000573 andMIR:MI0000706). The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies .
MI0000083	MIPF0000043	GUGGCCUCGUUCAAGUAAUCCAGGAUAGGCUGUGCAGGUCCCAAUGGGCCUAUUCUUGGUUACUUGCACGGGGACGC	MIMAT0004499 hsa-miR-26a-1-3p	CCUAUUCUUGGUUACUUGCACG	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

MYH10,C17orf51,RPS27A,OGT,GSK3B,SMAD1,FASN,MTRF1,TRAP1,CEPT1,SLC25A30,HMGA2,DCAF7,PLAG1,EZH2
more » MYH10,C17orf51,RPS27A,OGT,GSK3B,SMAD1,FASN,MTRF1,TRAP1,CEPT1,SLC25A30,HMGA2,DCAF7,PLAG1,EZH2,RND2,CDC6,PTENP1,STRADB,ESR1,USP7,KCTD5,RAB18,CCDC43,BBX,LSM14A,SLC35A4,MYC,RPS24,SFMBT1,WWP2,E2F7,DDB1,ACTL8,MTDH,HNRNPU,BTBD3,C16orf57,SPTBN1,ABCA1,C14orf37,MFHAS1,COX1,PNMA2,TXNL1,CDK8,ASCC2,HSPA8,MTRF1L,HIST2H2AA3,ANO3,TFAM,RPL13,SERBP1,COX3,MYO10,ZNF207,ABCB9,HIST4H4,GIT2,C6orf47,TTN,SARS,ATP5A1,CTBP1,ARCN1,EEF1B2,CTC1,FRAT2,ATP1A1,HIST1H4J,GLG1,RBM39,CTGF,RPL13A,PIKFYVE,RASA1,OLA1,TBC1D16,ARL4C,TMCC3,CCND3,IL6,CPEB2,TXLNG,RRM2,UBTF,ACTN4,CNTD2,NKX2-5,MCM3AP,FER,MRPL51,CAMKV,HIST1H4E,EIF2C1,FAM134A,PCYT1A,EPG5,PSMA3,CCNE1,KDM5C,ATP7B,BTBD9,TYW1,HOXC8,PTTG1,OBFC2A,COPB1,LYST,AURKAIP1,CLIC4,FAM20B,ARHGEF1,UBE2A,ABCB7,MSL3,SYCE1,TUT1,CTR9,LRP6,CSRP2BP,SETD2,UBA2,SMAD4,CPEB4,PPP1CC,TXNDC11,LIF,GDAP1,CNBP,CCND2,PIGT,SEC31A,IFNB1,HIAT1,TKT,PPIA,MSH6,DST,COASY,RHOBTB1,NUP205,TPGS2,ELOVL6,CCNE2,ZNF506,SHC2,ALG10B,UBR4,AHR,WEE1,TUBG1,CDK6,MCL1,NUAK1,SDCBP,LINS,BDNF,HMGA1,CHEK1,RB1,ZNF233,CPEB3,GGA2,SLC35B4,SET,YWHAE,DNMT1,SLC25A5,WBSCR16,AHRR,TP53INP1,CFLAR,KIAA1704,SCRN1,TCP1,ZNF703,FOXO3,PTEN,MAP3K2,DHX15,RPS26,CA2,NOS2,ZNF814,BAG4

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa04110	Cell cycle	CHEK1,GSK3B,WEE1,RB1,PTTG1,CCNE2,CDK6,CDC6,SMAD4,CCND2,YWHAE,CCNE1,MYC,CCND3,	3.09E-8
hsa04115	p53 signaling pathway	CDK6,CCNE2,PTEN,CHEK1,PTENP1,CCND2,RRM2,CCNE1,CCND3,	6.40E-5
hsa05222	Small cell lung cancer	CDK6,CCNE2,PTEN,NOS2,PTENP1,RB1,CCNE1,MYC,	1.57E-2
hsa05220	Chronic myeloid leukemia	CTBP1,CDK6,SHC2,SMAD4,RB1,MYC,	5.27E-2
hsa04310	Wnt signaling pathway	CTBP1,LRP6,GSK3B,CCND2,SMAD4,FRAT2,MYC,CCND3,	7.48E-2

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0007049	cell cycle	STRADB,GSK3B,HMGA2,AHR,PSMA3,DST,E2F7,MSH6,TTN,TUBG1,SYCE1,CHEK1,WEE1,RB1,RPS27A,PTTG1,CDK6,CCNE2,TP53INP1,CSRP2BP,PPP1CC,CDC6,MYH10,CCND2,CCNE1,MYC,CCND3,	8.10E-7
GO:0022402	cell cycle process	TUBG1,CHEK1,GSK3B,SYCE1,WEE1,HMGA2,RB1,RPS27A,PSMA3,PTTG1,DST,CDK6,TP53INP1,CSRP2BP,CDC6,MYH10,CCND2,MSH6,TTN,CCNE1,MYC,	7.76E-6
GO:0051301	cell division	SYCE1,WEE1,HMGA2,RB1,PTTG1,RASA1,CCNE2,CDK6,CDC6,PPP1CC,MYH10,CCND2,CCNE1,CCND3,	3.71E-5
GO:0051726	regulation of cell cycle	AURKAIP1,PTEN,PTENP1,CHEK1,RB1,HSPA8,CCNE2,CDK6,LIF,CDC6,CCND2,DDB1,MYC,CCND3,OBFC2A,	1.19E-4
GO:0051276	chromosome organization	EZH2,KDM5C,HMGA2,RB1,HMGA1,DNMT1,PTTG1,UBE2A,MSL3,CSRP2BP,HIST4H4,SET,HIST2H2AA3,SETD2,MSH6,HIST1H4J,TTN,CTR9,HIST1H4E,	1.51E-4

GO:0046907	intracellular transport	SLC25A30,MCM3AP,STRADB,SEC31A,ABCA1,SPTBN1,GSK3B,COPB1,ARCN1,HSPA8,PIKFYVE,NUP205,DST,ATP7B,SDCBP,LYST,SET,MYH10,YWHAE,GGA2,	2.00E-4
GO:0006259	DNA metabolic process	MCM3AP,CHEK1,RRM2,HMGA1,PPIA,DNMT1,PTTG1,UBE2A,CCNE2,CDC6,SET,TFAM,CTGF,MSH6,DDB1,MYC,OBFC2A,	2.45E-4
GO:0008285	negative regulation of cell proliferation	CTBP1,PTEN,ADM,PTENP1,CHEK1,RB1,ATP5A1,CDK6,E2F7,IFNB1,CDC6,BDNF,SMAD4,IL6,SMAD1,	2.80E-4
GO:0045597	positive regulation of cell differentiation	LIF,CA2,ARHGEF1,FOXO3,BDNF,SMAD4,RB1,CCNE1,NKX2-5,IL6,SMAD1,	3.22E-4
GO:0000079	regulation of cyclin-dependent protein kinase activity	CCNE2,PTEN,CDC6,CHEK1,PTENP1,CCND2,CCND3,	3.83E-4
GO:0006325	chromatin organization	EZH2,KDM5C,HMGA2,RB1,HMGA1,DNMT1,UBE2A,MSL3,CSRP2BP,HIST4H4,SET,HIST2H2AA3,SETD2,HIST1H4J,CTR9,HIST1H4E,	4.35E-4
GO:0006916	anti-apoptosis	BAG4,STRADB,CFLAR,GSK3B,BDNF,ESR1,NKX2-5,RPS27A,MYC,MCL1,	6.40E-4
GO:0042127	regulation of cell proliferation	CTBP1,PTEN,ADM,NOS2,CHEK1,PTENP1,RB1,ATP5A1,UBE2A,CDK6,E2F7,IFNB1,LIF,CDC6,BDNF,CCND2,SMAD4,IL6,NKX2-5,CNBP,SMAD1,MYC,	7.20E-4
GO:0010605	negative regulation of macromolecule metabolic process	WWP2,CTBP1,HOXC8,EIF2C1,RPS26,RB1,DNMT1,RPS27A,PSMA3,MTDH,IFNB1,CDC6,SET,MSH6,SMAD4,YWHAE,IL6,NKX2-5,SMAD1,MYC,	7.91E-4
GO:0043066	negative regulation of apoptosis	STRADB,BAG4,PTEN,GSK3B,PTENP1,ESR1,RPS27A,RASA1,MCL1,CFLAR,BDNF,NKX2-5,IL6,MYC,	8.21E-4
GO:0034621	cellular macromolecular complex subunit organization	MTRF1L,MTRF1,TUBG1,TCP1,HMGA1,NUP205,HIST4H4,SET,HIST2H2AA3,TFAM,HIST1H4J,SMAD4,TTN,HIST1H4E,SMAD1,	8.84E-4
GO:0045767	regulation of anti-apoptosis	ADM,SERBP1,IL6,SMAD1,RASA1,	9.25E-4
GO:0043069	negative regulation of programmed cell death	STRADB,BAG4,PTEN,GSK3B,PTENP1,ESR1,RPS27A,RASA1,MCL1,CFLAR,BDNF,NKX2-5,IL6,MYC,	9.28E-4
GO:0042981	regulation of apoptosis	AHRR,STRADB,BAG4,PTEN,FOXO3,GSK3B,PTENP1,ESR1,RPS27A,MCL1,RASA1,TP53INP1,IFNB1,CFLAR,LYST,BDNF,MSH6,ACTN4,YWHAE,IL6,NKX2-5,MYC,	9.38E-4
GO:0060548	negative regulation of cell death	STRADB,BAG4,PTEN,GSK3B,PTENP1,ESR1,RPS27A,RASA1,MCL1,CFLAR,BDNF,NKX2-5,IL6,MYC,	9.50E-4
GO:0043067	regulation of programmed cell death	AHRR,STRADB,BAG4,PTEN,FOXO3,GSK3B,PTENP1,ESR1,RPS27A,MCL1,RASA1,TP53INP1,IFNB1,CFLAR,LYST,BDNF,MSH6,ACTN4,YWHAE,IL6,NKX2-5,MYC,	1.05E-2
GO:0010941	regulation of cell death	AHRR,STRADB,BAG4,PTEN,FOXO3,GSK3B,PTENP1,ESR1,RPS27A,MCL1,RASA1,TP53INP1,IFNB1,CFLAR,LYST,BDNF,MSH6,ACTN4,YWHAE,IL6,NKX2-5,MYC,	1.10E-2
GO:0032268	regulation of cellular protein metabolic process	AURKAIP1,CPEB2,MTRF1,EIF2C1,DNMT1,RPS27A,PSMA3,LIF,SET,CCND2,SMAD4,YWHAE,MAP3K2,IL6,CCND3,	1.17E-2
GO:0045637	regulation of myeloid cell differentiation	CDK6,LIF,CA2,FOXO3,HIST4H4,HIST1H4J,RB1,HIST1H4E,	1.26E-2
GO:0051094	positive regulation of developmental process	LIF,CA2,ARHGEF1,FOXO3,BDNF,SMAD4,RB1,CCNE1,NKX2-5,IL6,SMAD1,	1.43E-2
GO:0006260	DNA replication	MCM3AP,CCNE2,CDC6,SET,CHEK1,TFAM,CTGF,RRM2,HMGA1,	1.61E-2
GO:0031399	regulation of protein modification process	LIF,SET,CCND2,SMAD4,YWHAE,DNMT1,MAP3K2,IL6,PSMA3,RPS27A,CCND3,	2.22E-2
GO:0022403	cell cycle phase	TUBG1,SYCE1,CHEK1,WEE1,HMGA2,RB1,PTTG1,CDK6,CDC6,MSH6,CCND2,TTN,CCNE1,	3.06E-2
GO:0022411	cellular component disassembly	MTRF1L,MTRF1,SET,HMGA1,MYC,	3.21E-2
GO:0032984	macromolecular complex disassembly	MTRF1L,MTRF1,SET,HMGA1,	3.21E-2
GO:0034623	cellular macromolecular complex disassembly	MTRF1L,MTRF1,SET,HMGA1,	3.21E-2
GO:0000278	mitotic cell cycle	CDK6,CDC6,CHEK1,CCND2,TTN,HMGA2,WEE1,RB1,CCNE1,PSMA3,RPS27A,PTTG1,	3.74E-2
GO:0006917	induction of apoptosis	AHRR,PTEN,TP53INP1,IFNB1,CFLAR,LYST,FOXO3,PTENP1,MSH6,YWHAE,RPS27A,MYC,	3.98E-2
GO:0000075	cell cycle checkpoint	CCNE2,CDC6,CHEK1,RB1,DDB1,OBFC2A,	4.01E-2
GO:0019220	regulation of phosphate metabolic process	STRADB,PTEN,PTENP1,CHEK1,RB1,CCNE2,LIF,CDC6,CCND2,SMAD4,TTN,YWHAE,MAP3K2,IL6,CCND3,	4.05E-2
GO:0051174	regulation of phosphorus metabolic process	STRADB,PTEN,PTENP1,CHEK1,RB1,CCNE2,LIF,CDC6,CCND2,SMAD4,TTN,YWHAE,MAP3K2,IL6,CCND3,	4.05E-2
GO:0012502	induction of programmed cell death	AHRR,PTEN,TP53INP1,IFNB1,CFLAR,LYST,FOXO3,PTENP1,MSH6,YWHAE,RPS27A,MYC,	4.07E-2
GO:0045768	positive regulation of anti-apoptosis	ADM,IL6,SMAD1,RASA1,	4.86E-2
GO:0051130	positive regulation of cellular component organization	ARHGEF1,GSK3B,SMAD4,AHR,ACTN4,DNMT1,NKX2-5,SMAD1,	4.99E-2
GO:0032270	positive regulation of cellular protein metabolic process	AURKAIP1,LIF,CCND2,SMAD4,DNMT1,IL6,PSMA3,RPS27A,CCND3,	5.62E-2
GO:0031401	positive regulation of protein modification process	LIF,CCND2,SMAD4,DNMT1,IL6,PSMA3,RPS27A,CCND3,	5.96E-2
GO:0044087	regulation of cellular component biogenesis	PTEN,SPTBN1,GSK3B,PTENP1,AHR,NKX2-5,RPS27A,RASA1,	6.03E-2
GO:0006414	translational elongation	RPS24,RPL13,EEF1B2,RPL13A,RPS26,RPS27A,	6.23E-2
GO:0045639	positive regulation of myeloid cell differentiation	LIF,CA2,FOXO3,RB1,	6.36E-2
GO:0051329	interphase of mitotic cell cycle	CDK6,CDC6,CHEK1,CCND2,RB1,CCNE1,	6.76E-2
GO:0055006	cardiac cell development	MYH10,TTN,NKX2-5,	6.78E-2
GO:0055013	cardiac muscle cell development	MYH10,TTN,NKX2-5,	6.78E-2
GO:0048545	response to steroid hormone stimulus	PTEN,ADM,CA2,PTENP1,CCND2,ESR1,CCNE1,NKX2-5,IL6,	6.87E-2
GO:0051247	positive regulation of protein metabolic process	AURKAIP1,LIF,CCND2,SMAD4,DNMT1,IL6,PSMA3,RPS27A,CCND3,	7.18E-2
GO:0010628	positive regulation of gene expression	FOXO3,RB1,AHR,HMGA1,ESR1,DNMT1,RPS27A,LIF,SMAD4,NKX2-5,CNBP,IL6,CCNE1,SMAD1,MYC,	7.30E-2
GO:0043627	response to estrogen stimulus	PTEN,CA2,PTENP1,CCND2,ESR1,CCNE1,NKX2-5,	7.32E-2
GO:0051325	interphase	CDK6,CDC6,CHEK1,CCND2,RB1,CCNE1,	7.62E-2
GO:0042325	regulation of phosphorylation	STRADB,PTEN,PTENP1,CHEK1,RB1,CCNE2,LIF,CDC6,SMAD4,CCND2,TTN,MAP3K2,IL6,CCND3,	7.74E-2
GO:0007242	intracellular signaling cascade	STRADB,ADM,RAB18,ABCA1,RHOBTB1,GSK3B,ESR1,HIST4H4,HIST1H4J,MSH6,HIST1H4E,NOS2,CHEK1,RB1,PIKFYVE,FER,RASA1,SHC2,ARHGEF1,SDCBP,CTGF,ARL4C,YWHAE,MAP3K2,CCNE1,SMAD1,RND2,	9.35E-2
GO:0010604	positive regulation of macromolecule metabolic process	AURKAIP1,FOXO3,RB1,AHR,HMGA1,ESR1,DNMT1,RPS27A,PSMA3,LIF,CCND2,SMAD4,CCNE1,NKX2-5,CNBP,IL6,SMAD1,MYC,CCND3,	9.86E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value