ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-25

MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0004498 hsa-miR-25-5p	AGGCGGAGACUUGGGCAAUUG
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0000081 hsa-miR-25-3p	CAUUGCACUUGUCUCGGUCUGA
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0004498 hsa-miR-25-5p	AGGCGGAGACUUGGGCAAUUG
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0000081 hsa-miR-25-3p	CAUUGCACUUGUCUCGGUCUGA
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0004498 hsa-miR-25-5p	AGGCGGAGACUUGGGCAAUUG
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0000081 hsa-miR-25-3p	CAUUGCACUUGUCUCGGUCUGA
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0004498 hsa-miR-25-5p	AGGCGGAGACUUGGGCAAUUG
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0000081 hsa-miR-25-3p	CAUUGCACUUGUCUCGGUCUGA
MI0000082	MIPF0000013	GGCCAGUGUUGAGAGGCGGAGACUUGGGCAAUUGCUGGACGCUGCCCUGGGCAUUGCACUUGUCUCGGUCUGACAGUGCCGGCC	MIMAT0000081 hsa-miR-25-3p	CAUUGCACUUGUCUCGGUCUGA

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

RECK,EXOC6B,ANXA11,KAT2B,PDXP,TRAP1,ACSS1,TMEM173,EP300,FNBP1,CEP85,KATNB1,TUBB,EZH2,EIF4B
more » RECK,EXOC6B,ANXA11,KAT2B,PDXP,TRAP1,ACSS1,TMEM173,EP300,FNBP1,CEP85,KATNB1,TUBB,EZH2,EIF4B,ATN1,BTBD7,CCL26,ETFA,CDK4,ITM2B,PKDCC,CTSE,ZNF682,DDX23,NDUFAF3,HNRNPA1,CDKN1C,AIM1,EIF5A,NDNL2,SUPT16H,SLC4A7,SMAP2,HIST2H2BF,ARPC3,TLN1,RBM27,ZNF557,ARPC5L,CHCHD10,RCOR1,GPBP1,HSPA8,WDR11,DNM1L,HIST2H2AA3,DKK4,PRMT5,PRRC2A,SEMA4D,NDE1,PEX5,EIF5A2,CCDC96,TSHZ3,DENND5A,PHKA1,KIAA0528,TMUB1,EIF4G2,NSMAF,PDK2,UBR1,CTC1,SMAP1,MLEC,RPS3A,NAT1,PGRMC1,ZDHHC8,SETD1B,SNTB2,ELF4,WDR4,KIF23,NOTCH2,COPS3,TUSC3,BPTF,TNPO2,WDR85,ACP1,PRPF8,ANKRD18A,PHTF1,HYAL1,KIF22,ACTL6A,KIAA0284,SLC12A4,FECH,MBD1,PLEKHA5,KCTD15,PARL,EIF2C1,PELO,SNPH,NPM1,LOXHD1,SRRM2,TRAF3IP1,CLSPN,ROBO1,DHX9,RAPGEF1,STAG1,SCAF4,CDH1,GAPDH,CDKN1A,SYNPR,PHB2,SMAD7,C2orf29,GPR157,TP53,ARHGAP17,SERTAD3,KLF4,PDGFRL,DENND4A,EME2,RPS14,EMD,SREBF1,BCL2L11,RPL26,CABIN1,BZW1,RNASEH2A,MARCH6,PRKAR1A,DEAF1,SBNO2,CCNE2,NVL,NHP2,PCDH7,C10orf118,SSRP1,STXBP1,RYR2,TUBB4B,ANKIB1,DCTN1,AP3M1,RPS2,XPC,RNGTT,DDX49,TSFM,ASS1,NRN1,UBAP2L,EZR,CHRAC1,FNDC3B,VMP1,FAM18B1,HMBS,MDM2,RPSA,ZNF346,RPS28,HSP90AA1,PSMB4,ZBTB8OS,TRAPPC2,NOL12,ITGB1,ADAMTSL1,MPP6,EEF1A1,TUBGCP4,YBX1,RPL7A,CLIC1,SRPR,CTNNBL1

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa05130	Pathogenic Escherichia coli infection	TUBB4B,EZR,ITGB1,ARPC5L,ARPC3,TUBB,CDH1,	9.71E-5
hsa04110	Cell cycle	CCNE2,STAG1,EP300,CDK4,MDM2,CDKN1C,CDKN1A,TP53,	1.28E-2
hsa05219	Bladder cancer	CDK4,MDM2,CDKN1A,TP53,CDH1,	2.23E-2
hsa03010	Ribosome	RPL7A,RPS3A,RPL26,RPSA,RPS2,RPS28,	5.84E-2
hsa05215	Prostate cancer	CCNE2,HSP90AA1,EP300,MDM2,CDKN1A,TP53,	6.42E-2

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0006414	translational elongation	TSFM,RPL7A,RPS3A,RPL26,EEF1A1,RPSA,RPS14,RPS2,RPS28,	1.02E-5
GO:0006412	translation	PELO,RPL7A,RPL26,RPS3A,EEF1A1,RPS14,RPS2,RPS28,EIF4G2,TSFM,EIF4B,EIF5A,EIF5A2,RPSA,	4.21E-5
GO:0007049	cell cycle	CLSPN,PELO,NOTCH2,KAT2B,EP300,NPM1,CDK4,MDM2,CDKN1C,KIF22,PSMB4,CDKN1A,TP53,EIF4G2,CCNE2,ITGB1,DCTN1,STAG1,NDE1,KIF23,TUBB,KATNB1,	5.23E-5
GO:0022402	cell cycle process	NOTCH2,KAT2B,NPM1,CDK4,MDM2,KIF22,CDKN1C,PSMB4,CDKN1A,TP53,EIF4G2,ITGB1,DCTN1,STAG1,NDE1,KIF23,TUBB,KATNB1,	8.10E-5
GO:0006325	chromatin organization	EZH2,CABIN1,KAT2B,EP300,NPM1,SETD1B,PRMT5,CHRAC1,SUPT16H,RCOR1,HIST2H2BF,HIST2H2AA3,BPTF,ACTL6A,	1.61E-4

GO:0051276	chromosome organization	EZH2,PELO,CABIN1,KAT2B,EP300,NPM1,SETD1B,PRMT5,CHRAC1,TP53,SUPT16H,RCOR1,HIST2H2BF,HIST2H2AA3,BPTF,ACTL6A,	1.61E-4
GO:0000278	mitotic cell cycle	KIF22,CDKN1C,MDM2,CDK4,PSMB4,CDKN1A,ITGB1,DCTN1,STAG1,KIF23,NDE1,TUBB,KATNB1,	4.91E-4
GO:0018205	peptidyl-lysine modification	KAT2B,EIF5A,EP300,EIF5A2,	6.77E-4
GO:0043933	macromolecular complex subunit organization	NPM1,MDM2,PRMT5,TNPO2,MPP6,RPS14,TP53,SUPT16H,PEX5,TUBB4B,NDUFAF3,TUBGCP4,HSP90AA1,HIST2H2BF,TUBB,HIST2H2AA3,DDX23,CDH1,	1.14E-2
GO:0034621	cellular macromolecular complex subunit organization	SUPT16H,TUBB4B,NDUFAF3,HSP90AA1,HIST2H2BF,NPM1,HIST2H2AA3,TUBB,PRMT5,TNPO2,RPS14,DDX23,	1.27E-2
GO:0065003	macromolecular complex assembly	NPM1,MDM2,PRMT5,TNPO2,MPP6,RPS14,TP53,PEX5,TUBB4B,NDUFAF3,TUBGCP4,HIST2H2BF,HSP90AA1,TUBB,HIST2H2AA3,DDX23,CDH1,	1.52E-2
GO:0010608	posttranscriptional regulation of gene expression	EIF4G2,EIF5A,EIF4B,EIF5A2,EIF2C1,CDK4,DHX9,SMAD7,YBX1,	1.65E-2
GO:0006396	RNA processing	SRRM2,RNGTT,RPL26,ZNF346,PRMT5,DHX9,RPS14,RPS28,HNRNPA1,PRPF8,NHP2,WDR4,DDX23,SCAF4,YBX1,	1.71E-2
GO:0034622	cellular macromolecular complex assembly	TUBB4B,NDUFAF3,HSP90AA1,HIST2H2BF,NPM1,HIST2H2AA3,TUBB,PRMT5,TNPO2,RPS14,DDX23,	1.82E-2
GO:0043243	positive regulation of protein complex disassembly	EIF5A,EIF5A2,KATNB1,	2.18E-2
GO:0016568	chromatin modification	RCOR1,EZH2,CABIN1,KAT2B,EP300,SETD1B,PRMT5,BPTF,CHRAC1,ACTL6A,	2.29E-2
GO:0051726	regulation of cell cycle	CCNE2,ITGB1,NPM1,PRMT5,CDK4,MDM2,CDKN1C,HSPA8,CDKN1A,XPC,TP53,	2.44E-2
GO:0022613	ribonucleoprotein complex biogenesis	RPL7A,NPM1,NHP2,RPL26,PRMT5,RPS14,DDX23,RPS28,	2.78E-2
GO:0022406	membrane docking	STXBP1,EZR,SNPH,EXOC6B,	4.02E-2
GO:0022403	cell cycle phase	ITGB1,DCTN1,STAG1,NDE1,KIF23,TUBB,KATNB1,CDK4,MDM2,CDKN1C,KIF22,CDKN1A,	4.03E-2
GO:0007006	mitochondrial membrane organization	PEX5,HSP90AA1,DNM1L,TP53,	4.40E-2
GO:0007050	cell cycle arrest	EIF4G2,NOTCH2,KAT2B,CDKN1C,CDKN1A,TP53,	4.43E-2
GO:0016071	mRNA metabolic process	SRRM2,HSPA1B,HNRNPA1,EIF2C1,PRPF8,RNGTT,PRMT5,DHX9,SCAF4,DDX23,YBX1,	5.37E-2
GO:0042274	ribosomal small subunit biogenesis	NPM1,RPS14,RPS28,	5.57E-2
GO:0006917	induction of apoptosis	TUBB4B,NOTCH2,EIF5A,ITM2B,TUBB,RPS3A,CDKN1A,RYR2,BCL2L11,TP53,	6.34E-2
GO:0012502	induction of programmed cell death	TUBB4B,NOTCH2,EIF5A,ITM2B,TUBB,RPS3A,CDKN1A,RYR2,BCL2L11,TP53,	6.46E-2
GO:0032535	regulation of cellular component size	NOTCH2,NPM1,ARPC5L,EP300,ARPC3,CDK4,SERTAD3,CDKN1A,TP53,	7.49E-2
GO:0042254	ribosome biogenesis	RPL7A,NPM1,NHP2,RPL26,RPS14,RPS28,	8.97E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value