Gene ontology terms enriched for interacted genes |
GO terms | GO terms description | target genes enrich in GO term | p-value |
|
GO:0007389
|
pattern specification process |
TCF7L1,HOXB5,EP300,BMI1,NOTCH1,FLT1,GATA4,ZEB2,RNF2,VEGFA,TGFBR1,ZEB1,SMAD2, |
4.68E-12 |
GO:0035295
|
tube development |
BCL2,VEGFA,EP300,NOTCH1,FLT1,KDR,ZFPM2,GATA4,TGFBR1,ZEB2,SMAD2, |
3.34E-10 |
GO:0003002
|
regionalization |
RNF2,TCF7L1,HOXB5,BMI1,EP300,NOTCH1,GATA4,TGFBR1,ZEB2,SMAD2, |
2.77E-9 |
GO:0009952
|
anterior/posterior pattern formation |
RNF2,TCF7L1,HOXB5,EP300,NOTCH1,GATA4,TGFBR1,ZEB2,SMAD2, |
4.04E-9 |
GO:0045935
|
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
TCF7L1,SHC1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
7.04E-9 |
|
GO:0051173
|
positive regulation of nitrogen compound metabolic process |
TCF7L1,SHC1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
1.02E-8 |
GO:0042127
|
regulation of cell proliferation |
BCL2,SHC1,BMI1,NOTCH1,FLT1,KDR,GATA4,E2F3,VEGFA,BAP1,KLF11,ETS1,TGFBR1,ZEB1,SMAD2, |
1.18E-8 |
GO:0010557
|
positive regulation of macromolecule biosynthetic process |
TCF7L1,SHC1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
1.23E-8 |
GO:0031328
|
positive regulation of cellular biosynthetic process |
TCF7L1,SHC1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
2.14E-8 |
GO:0045941
|
positive regulation of transcription |
TCF7L1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
2.46E-8 |
GO:0009891
|
positive regulation of biosynthetic process |
TCF7L1,SHC1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
2.55E-8 |
GO:0010628
|
positive regulation of gene expression |
TCF7L1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
3.41E-8 |
GO:0010604
|
positive regulation of macromolecule metabolic process |
BCL2,TCF7L1,SHC1,EP300,NOTCH1,GATA4,CREB1,E2F3,VEGFA,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
3.49E-8 |
GO:0045893
|
positive regulation of transcription, DNA-dependent |
VEGFA,TCF7L1,EP300,NOTCH1,NFAT5,ETS1,ZFPM2,CREB1,GATA4,E2F3,ZEB1,SMAD2, |
4.74E-8 |
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter |
VEGFA,TCF7L1,EP300,NOTCH1,NFAT5,ETS1,ZFPM2,CREB1,GATA4,ZEB1,SMAD2, |
5.08E-8 |
GO:0051254
|
positive regulation of RNA metabolic process |
VEGFA,TCF7L1,EP300,NOTCH1,NFAT5,ETS1,ZFPM2,CREB1,GATA4,E2F3,ZEB1,SMAD2, |
5.16E-8 |
GO:0030324
|
lung development |
VEGFA,EP300,NOTCH1,KDR,ZFPM2,TGFBR1,SMAD2, |
3.01E-7 |
GO:0030323
|
respiratory tube development |
VEGFA,EP300,NOTCH1,KDR,ZFPM2,TGFBR1,SMAD2, |
3.59E-7 |
GO:0006357
|
regulation of transcription from RNA polymerase II promoter |
TCF7L1,EP300,NOTCH1,GATA4,CREB1,RNF2,VEGFA,KLF11,NFAT5,ETS1,ZFPM2,ZEB1,SMAD2, |
3.93E-7 |
GO:0060541
|
respiratory system development |
VEGFA,EP300,NOTCH1,KDR,ZFPM2,TGFBR1,SMAD2, |
5.04E-7 |
GO:0035239
|
tube morphogenesis |
BCL2,VEGFA,NOTCH1,FLT1,KDR,GATA4,ZEB2, |
1.31E-6 |
GO:0007167
|
enzyme linked receptor protein signaling pathway |
VEGFA,ERBB2IP,SHC1,FLT1,KDR,CREB1,TGFBR1,SMAD2,PTPRD, |
3.87E-6 |
GO:0051272
|
positive regulation of cell motion |
BCL2,VEGFA,FLT1,ETS1,KDR,TGFBR1, |
7.47E-6 |
GO:0006355
|
regulation of transcription, DNA-dependent |
TCF7L1,HOXB5,EP300,NOTCH1,RERE,GATA4,CREB1,E2F3,ZEB2,RNF2,VEGFA,KLF11,NFAT5,ETS1,ZFPM2,ZEB1,SMAD2, |
9.12E-6 |
GO:0051252
|
regulation of RNA metabolic process |
TCF7L1,HOXB5,EP300,NOTCH1,RERE,GATA4,CREB1,E2F3,ZEB2,RNF2,VEGFA,KLF11,NFAT5,ETS1,ZFPM2,ZEB1,SMAD2, |
1.21E-5 |
GO:0008284
|
positive regulation of cell proliferation |
BCL2,VEGFA,BMI1,SHC1,NOTCH1,FLT1,KDR,TGFBR1,E2F3, |
1.56E-5 |
GO:0048598
|
embryonic morphogenesis |
RNF2,HOXB5,NOTCH1,GATA4,TGFBR1,ZEB2,ZEB1,SMAD2, |
1.99E-5 |
GO:0048754
|
branching morphogenesis of a tube |
BCL2,VEGFA,NOTCH1,FLT1,KDR, |
3.16E-5 |
GO:0043009
|
chordate embryonic development |
HOXB5,EP300,ZFPM2,GATA4,TGFBR1,ZEB2,ZEB1,SMAD2, |
3.23E-5 |
GO:0009792
|
embryonic development ending in birth or egg hatching |
HOXB5,EP300,ZFPM2,GATA4,TGFBR1,ZEB2,ZEB1,SMAD2, |
3.42E-5 |
GO:0001763
|
morphogenesis of a branching structure |
BCL2,VEGFA,NOTCH1,FLT1,KDR, |
5.28E-5 |
GO:0045449
|
regulation of transcription |
TCF7L1,HOXB5,EP300,BMI1,NOTCH1,RERE,CREB1,GATA4,E2F3,ZEB2,RNF2,VEGFA,KLF11,NFAT5,ETS1,ZFPM2,TGFBR1,ZEB1,SMAD2, |
7.78E-5 |
GO:0006350
|
transcription |
TCF7L1,HOXB5,EP300,BMI1,NOTCH1,RERE,GATA4,CREB1,E2F3,ZEB2,RNF2,KLF11,NFAT5,ETS1,ZFPM2,ZEB1,SMAD2, |
7.87E-5 |
GO:0043193
|
positive regulation of gene-specific transcription |
NOTCH1,ETS1,CREB1,GATA4,SMAD2, |
9.96E-5 |
GO:0048568
|
embryonic organ development |
VEGFA,HOXB5,ZFPM2,GATA4,TGFBR1,ZEB1, |
1.12E-4 |
GO:0048565
|
gut development |
BCL2,NOTCH1,GATA4,TGFBR1, |
1.36E-4 |
GO:0051270
|
regulation of cell motion |
BCL2,VEGFA,FLT1,ETS1,KDR,TGFBR1, |
1.92E-4 |
GO:0048514
|
blood vessel morphogenesis |
VEGFA,NOTCH1,FLT1,KDR,ZFPM2,TGFBR1, |
2.90E-4 |
GO:0007507
|
heart development |
EP300,NOTCH1,ZFPM2,GATA4,TGFBR1,SMAD2, |
3.16E-4 |
GO:0035282
|
segmentation |
TCF7L1,BMI1,EP300,ZEB2, |
3.24E-4 |
GO:0001666
|
response to hypoxia |
BCL2,VEGFA,EP300,FLT1,TGFBR1, |
5.23E-4 |
GO:0032583
|
regulation of gene-specific transcription |
NOTCH1,ETS1,CREB1,GATA4,SMAD2, |
5.23E-4 |
GO:0001568
|
blood vessel development |
VEGFA,NOTCH1,FLT1,KDR,ZFPM2,TGFBR1, |
5.76E-4 |
GO:0045165
|
cell fate commitment |
BCL2,NOTCH1,KDR,TGFBR1,SMAD2, |
6.00E-4 |
GO:0070482
|
response to oxygen levels |
BCL2,VEGFA,EP300,FLT1,TGFBR1, |
6.33E-4 |
GO:0001944
|
vasculature development |
VEGFA,NOTCH1,FLT1,KDR,ZFPM2,TGFBR1, |
6.43E-4 |
GO:0048547
|
gut morphogenesis |
BCL2,NOTCH1,GATA4, |
1.01E-2 |
GO:0051094
|
positive regulation of developmental process |
BCL2,NOTCH1,ETS1,BAD,GATA4,SMAD2, |
1.01E-2 |
GO:0010464
|
regulation of mesenchymal cell proliferation |
VEGFA,KDR,ZEB1, |
1.14E-2 |
GO:0006351
|
transcription, DNA-dependent |
KLF11,NFAT5,ETS1,CREB1,GATA4,E2F3, |
1.26E-2 |
GO:0032774
|
RNA biosynthetic process |
KLF11,NFAT5,ETS1,CREB1,GATA4,E2F3, |
1.34E-2 |
GO:0045927
|
positive regulation of growth |
BCL2,EP300,CREB1,TGFBR1, |
1.44E-2 |
GO:0055123
|
digestive system development |
BCL2,NOTCH1,GATA4, |
1.56E-2 |
GO:0048546
|
digestive tract morphogenesis |
BCL2,NOTCH1,GATA4, |
1.56E-2 |
GO:0048729
|
tissue morphogenesis |
BCL2,TCF7L1,NOTCH1,ZEB2,SMAD2, |
1.57E-2 |
GO:0051674
|
localization of cell |
FLT1,ETS1,KDR,FN1,TGFBR1,ZEB2, |
1.58E-2 |
GO:0048870
|
cell motility |
FLT1,ETS1,KDR,FN1,TGFBR1,ZEB2, |
1.58E-2 |
GO:0016481
|
negative regulation of transcription |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
1.62E-2 |
GO:0030335
|
positive regulation of cell migration |
BCL2,VEGFA,FLT1,KDR, |
1.96E-2 |
GO:0040008
|
regulation of growth |
BCL2,EP300,SHC1,CREB1,GATA4,TGFBR1, |
2.50E-2 |
GO:0008361
|
regulation of cell size |
BCL2,ERBB2IP,EP300,CREB1,TGFBR1, |
2.57E-2 |
GO:0040017
|
positive regulation of locomotion |
BCL2,VEGFA,FLT1,KDR, |
2.58E-2 |
GO:0010629
|
negative regulation of gene expression |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
2.59E-2 |
GO:0045934
|
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
2.80E-2 |
GO:0030856
|
regulation of epithelial cell differentiation |
NOTCH1,TGFBR1,ZEB1, |
2.97E-2 |
GO:0051172
|
negative regulation of nitrogen compound metabolic process |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
3.00E-2 |
GO:0045892
|
negative regulation of transcription, DNA-dependent |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB1,SMAD2, |
3.01E-2 |
GO:0009798
|
axis specification |
RNF2,TCF7L1,SMAD2, |
3.18E-2 |
GO:0008285
|
negative regulation of cell proliferation |
BCL2,BAP1,KLF11,ETS1,ZEB1,SMAD2, |
3.20E-2 |
GO:0051253
|
negative regulation of RNA metabolic process |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB1,SMAD2, |
3.24E-2 |
GO:0007169
|
transmembrane receptor protein tyrosine kinase signaling pathway |
VEGFA,ERBB2IP,SHC1,FLT1,KDR, |
3.47E-2 |
GO:0060429
|
epithelium development |
BCL2,VEGFA,HOXB5,KDR,ZEB2, |
3.64E-2 |
GO:0045597
|
positive regulation of cell differentiation |
BCL2,NOTCH1,ETS1,BAD,SMAD2, |
3.75E-2 |
GO:0010558
|
negative regulation of macromolecule biosynthetic process |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
3.89E-2 |
GO:0006366
|
transcription from RNA polymerase II promoter |
KLF11,NFAT5,ETS1,GATA4,E2F3, |
4.06E-2 |
GO:0031327
|
negative regulation of cellular biosynthetic process |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
4.40E-2 |
GO:0009890
|
negative regulation of biosynthetic process |
RNF2,KLF11,TCF7L1,ZFPM2,ZEB2,ZEB1,SMAD2, |
4.88E-2 |
GO:0006796
|
phosphate metabolic process |
BCL2,PTPN12,SHC1,FLT1,KDR,CREB1,TGFBR1,SMAD2,PTPRD, |
4.89E-2 |
GO:0006793
|
phosphorus metabolic process |
BCL2,PTPN12,SHC1,FLT1,KDR,CREB1,TGFBR1,SMAD2,PTPRD, |
4.89E-2 |
GO:0007049
|
cell cycle |
SEPT7,RNF2,CCNE2,BCL2,ERBB2IP,EP300,E2F3,RASSF2, |
5.27E-2 |
GO:0051147
|
regulation of muscle cell differentiation |
BCL2,NOTCH1,ZEB1, |
5.33E-2 |
GO:0022604
|
regulation of cell morphogenesis |
VEGFA,KDR,FN1,SMAD2, |
5.84E-2 |
GO:0001541
|
ovarian follicle development |
BCL2,VEGFA,KDR, |
5.88E-2 |
GO:0001570
|
vasculogenesis |
VEGFA,KDR,ZFPM2, |
5.88E-2 |
GO:0048534
|
hemopoietic or lymphoid organ development |
BCL2,VEGFA,BMI1,KDR,TGFBR1, |
5.89E-2 |
GO:0048562
|
embryonic organ morphogenesis |
HOXB5,GATA4,TGFBR1,ZEB1, |
6.09E-2 |
GO:0042981
|
regulation of apoptosis |
BCL2,VEGFA,NOTCH1,ETS1,BAD,CREB1,XIAP,TGFBR1, |
6.38E-2 |
GO:0043067
|
regulation of programmed cell death |
BCL2,VEGFA,NOTCH1,ETS1,BAD,CREB1,XIAP,TGFBR1, |
6.73E-2 |
GO:0032535
|
regulation of cellular component size |
BCL2,ERBB2IP,EP300,CREB1,TGFBR1, |
6.80E-2 |
GO:0010941
|
regulation of cell death |
BCL2,VEGFA,NOTCH1,ETS1,BAD,CREB1,XIAP,TGFBR1, |
6.86E-2 |
GO:0016477
|
cell migration |
FLT1,KDR,FN1,TGFBR1,ZEB2, |
7.25E-2 |
GO:0002520
|
immune system development |
BCL2,VEGFA,BMI1,KDR,TGFBR1, |
7.25E-2 |
GO:0001525
|
angiogenesis |
VEGFA,NOTCH1,FLT1,KDR, |
8.18E-2 |
GO:0016202
|
regulation of striated muscle tissue development |
BCL2,NOTCH1,GATA4, |
8.64E-2 |
GO:0014031
|
mesenchymal cell development |
BCL2,NOTCH1,ZEB2, |
8.98E-2 |
GO:0048634
|
regulation of muscle development |
BCL2,NOTCH1,GATA4, |
8.98E-2 |
GO:0048762
|
mesenchymal cell differentiation |
BCL2,NOTCH1,ZEB2, |
8.98E-2 |
GO:0060485
|
mesenchyme development |
BCL2,NOTCH1,ZEB2, |
9.32E-2 |
GO:0042325
|
regulation of phosphorylation |
CCNE2,BCL2,SHC1,FLT1,TGFBR1,ZEB2, |
9.33E-2 |
GO:0008360
|
regulation of cell shape |
VEGFA,KDR,FN1, |
1.00E-1 |
GO:0006468
|
protein amino acid phosphorylation |
BCL2,SHC1,FLT1,KDR,CREB1,TGFBR1,SMAD2, |
1.00E-1 |
GO:0006928
|
cell motion |
FLT1,ETS1,KDR,FN1,TGFBR1,ZEB2, |
1.00E-1 |
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