Gene ontology terms enriched for interacted genes |
GO terms | GO terms description | target genes enrich in GO term | p-value |
|
GO:0009719
|
response to endogenous stimulus |
ERBB4,CCND1,PTEN,PIK3R3,KAT2B,NR4A2,TNF,PTENP1,TGFBR2,SOCS1,ESR1,IL6, |
4.86E-8 |
GO:0010033
|
response to organic substance |
ERBB4,CCND1,PTEN,PIK3R3,KAT2B,VPS4B,PTENP1,TNF,ESR1,SOCS1,NR4A2,TGFBR2,TLR2,IL6, |
1.28E-7 |
GO:0009725
|
response to hormone stimulus |
ERBB4,CCND1,PTEN,PIK3R3,KAT2B,TNF,PTENP1,TGFBR2,SOCS1,ESR1,IL6, |
2.73E-7 |
GO:0042127
|
regulation of cell proliferation |
ERBB4,CCND1,BMPR2,PTEN,KAT2B,SUZ12,PTENP1,HIF1A,TNF,CUL5,MYCN,SMAD4,TGFBR2,IL6, |
3.32E-7 |
GO:0048545
|
response to steroid hormone stimulus |
ERBB4,CCND1,PTEN,TNF,PTENP1,TGFBR2,SOCS1,ESR1,IL6, |
4.99E-7 |
|
GO:0042325
|
regulation of phosphorylation |
CCND1,BMPR2,PTEN,TNF,ATXN1,PTENP1,SMAD4,TGFBR2,SOCS1,IL6, |
1.93E-5 |
GO:0019220
|
regulation of phosphate metabolic process |
CCND1,BMPR2,PTEN,TNF,ATXN1,PTENP1,SMAD4,TGFBR2,SOCS1,IL6, |
2.58E-5 |
GO:0051174
|
regulation of phosphorus metabolic process |
CCND1,BMPR2,PTEN,TNF,ATXN1,PTENP1,SMAD4,TGFBR2,SOCS1,IL6, |
2.58E-5 |
GO:0006357
|
regulation of transcription from RNA polymerase II promoter |
MYCN,MECP2,RNF4,SUZ12,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
7.10E-5 |
GO:0008284
|
positive regulation of cell proliferation |
ERBB4,CCND1,MYCN,SUZ12,HIF1A,TNF,TGFBR2,IL6, |
7.65E-5 |
GO:0001932
|
regulation of protein amino acid phosphorylation |
CCND1,BMPR2,TNF,SMAD4,SOCS1,IL6, |
7.67E-5 |
GO:0001934
|
positive regulation of protein amino acid phosphorylation |
CCND1,BMPR2,TNF,SMAD4,IL6, |
7.84E-5 |
GO:0042327
|
positive regulation of phosphorylation |
CCND1,BMPR2,TNF,SMAD4,IL6, |
1.09E-4 |
GO:0010562
|
positive regulation of phosphorus metabolic process |
CCND1,BMPR2,TNF,SMAD4,IL6, |
1.23E-4 |
GO:0045937
|
positive regulation of phosphate metabolic process |
CCND1,BMPR2,TNF,SMAD4,IL6, |
1.23E-4 |
GO:0032722
|
positive regulation of chemokine production |
HIF1A,TNF,IL6, |
1.35E-4 |
GO:0043627
|
response to estrogen stimulus |
CCND1,PTEN,PTENP1,TGFBR2,SOCS1,ESR1, |
1.49E-4 |
GO:0042493
|
response to drug |
ERBB4,CCND1,PTEN,PTENP1,TGFBR2,SOCS1,TLR2, |
2.17E-4 |
GO:0007167
|
enzyme linked receptor protein signaling pathway |
ERBB4,BMPR2,PTEN,PIK3R3,RPS6KA5,PTENP1,SMAD4,TGFBR2, |
2.18E-4 |
GO:0035295
|
tube development |
BMPR2,HOXA5,MYCN,SMAD4,TGFBR2,BCL2L11, |
2.37E-4 |
GO:0010604
|
positive regulation of macromolecule metabolic process |
CCND1,BMPR2,RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,ESR1,IL6, |
2.49E-4 |
GO:0006355
|
regulation of transcription, DNA-dependent |
HOXA5,MECP2,KAT2B,SUZ12,RPS6KA5,HIF1A,ATXN1,TNF,ESR1,MYCN,RNF4,NR4A2,SMAD4,IL6, |
2.87E-4 |
GO:0008285
|
negative regulation of cell proliferation |
PTEN,KAT2B,TNF,PTENP1,SMAD4,CUL5,TGFBR2,IL6, |
2.92E-4 |
GO:0035239
|
tube morphogenesis |
HOXA5,MYCN,SMAD4,TGFBR2,BCL2L11, |
3.09E-4 |
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter |
RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
3.38E-4 |
GO:0051252
|
regulation of RNA metabolic process |
HOXA5,MECP2,KAT2B,SUZ12,RPS6KA5,HIF1A,ATXN1,TNF,ESR1,MYCN,RNF4,NR4A2,SMAD4,IL6, |
3.59E-4 |
GO:0051240
|
positive regulation of multicellular organismal process |
ERBB4,BMPR2,HIF1A,TNF,TLR2,IL6, |
3.82E-4 |
GO:0010628
|
positive regulation of gene expression |
RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,ESR1,IL6, |
6.11E-4 |
GO:0048754
|
branching morphogenesis of a tube |
HOXA5,MYCN,SMAD4,TGFBR2, |
6.20E-4 |
GO:0032642
|
regulation of chemokine production |
HIF1A,TNF,IL6, |
6.68E-4 |
GO:0051094
|
positive regulation of developmental process |
BMPR2,HIF1A,TNF,SMAD4,TGFBR2,IL6, |
6.92E-4 |
GO:0031399
|
regulation of protein modification process |
CCND1,BMPR2,TNF,SMAD4,SOCS1,IL6, |
9.04E-4 |
GO:0001763
|
morphogenesis of a branching structure |
HOXA5,MYCN,SMAD4,TGFBR2, |
9.06E-4 |
GO:0045935
|
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
RNF4,ABCA1,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
9.33E-4 |
GO:0032755
|
positive regulation of interleukin-6 production |
TNF,TLR2,IL6, |
1.08E-2 |
GO:0051173
|
positive regulation of nitrogen compound metabolic process |
RNF4,ABCA1,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
1.12E-2 |
GO:0045449
|
regulation of transcription |
HOXA5,MECP2,KAT2B,SUZ12,RPS6KA5,TNF,HIF1A,ATXN1,PRMT5,ESR1,MYCN,RNF4,NR4A2,SMAD4,TLR2,IL6, |
1.13E-2 |
GO:0001817
|
regulation of cytokine production |
HIF1A,TNF,SMAD4,TLR2,IL6, |
1.17E-2 |
GO:0045893
|
positive regulation of transcription, DNA-dependent |
RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
1.26E-2 |
GO:0051254
|
positive regulation of RNA metabolic process |
RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
1.32E-2 |
GO:0031401
|
positive regulation of protein modification process |
CCND1,BMPR2,TNF,SMAD4,IL6, |
1.32E-2 |
GO:0010647
|
positive regulation of cell communication |
ERBB4,HIF1A,TNF,SMAD4,ESR1,IL6, |
1.47E-2 |
GO:0001819
|
positive regulation of cytokine production |
HIF1A,TNF,TLR2,IL6, |
1.59E-2 |
GO:0031328
|
positive regulation of cellular biosynthetic process |
RNF4,ABCA1,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
1.60E-2 |
GO:0009891
|
positive regulation of biosynthetic process |
RNF4,ABCA1,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
1.74E-2 |
GO:0030324
|
lung development |
BMPR2,HOXA5,MYCN,TGFBR2, |
2.09E-2 |
GO:0030323
|
respiratory tube development |
BMPR2,HOXA5,MYCN,TGFBR2, |
2.28E-2 |
GO:0009991
|
response to extracellular stimulus |
CCND1,BMPR2,PTEN,NR4A2,PTENP1,TGFBR2, |
2.39E-2 |
GO:0007169
|
transmembrane receptor protein tyrosine kinase signaling pathway |
ERBB4,BMPR2,PTEN,PIK3R3,RPS6KA5,PTENP1, |
2.56E-2 |
GO:0060541
|
respiratory system development |
BMPR2,HOXA5,MYCN,TGFBR2, |
2.68E-2 |
GO:0045597
|
positive regulation of cell differentiation |
BMPR2,HIF1A,SMAD4,TGFBR2,IL6, |
2.77E-2 |
GO:0048661
|
positive regulation of smooth muscle cell proliferation |
TNF,TGFBR2,IL6, |
2.88E-2 |
GO:0032270
|
positive regulation of cellular protein metabolic process |
CCND1,BMPR2,TNF,SMAD4,IL6, |
2.95E-2 |
GO:0045941
|
positive regulation of transcription |
RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
2.95E-2 |
GO:0016192
|
vesicle-mediated transport |
RAB13,NPEPL1,VPS4B,ABCA1,KDELR2,TGFBR2,RAB14, |
3.28E-2 |
GO:0051247
|
positive regulation of protein metabolic process |
CCND1,BMPR2,TNF,SMAD4,IL6, |
3.43E-2 |
GO:0044093
|
positive regulation of molecular function |
CCND1,NR4A2,HIF1A,TNF,TGFBR2,TLR2,IL6, |
3.57E-2 |
GO:0016570
|
histone modification |
RPS6KA5,SUZ12,KAT2B,PRMT5, |
3.79E-2 |
GO:0007242
|
intracellular signaling cascade |
CCND1,RAB13,RNF4,RPS6KA5,ABCA1,TNF,SOCS1,TLR2,ESR1,RAB14, |
3.81E-2 |
GO:0032675
|
regulation of interleukin-6 production |
TNF,TLR2,IL6, |
3.87E-2 |
GO:0042981
|
regulation of apoptosis |
PTEN,NR4A2,TNF,PTENP1,CUL5,TLR2,ESR1,BCL2L11,IL6, |
3.97E-2 |
GO:0016569
|
covalent chromatin modification |
RPS6KA5,SUZ12,KAT2B,PRMT5, |
4.15E-2 |
GO:0043067
|
regulation of programmed cell death |
PTEN,NR4A2,TNF,PTENP1,CUL5,TLR2,ESR1,BCL2L11,IL6, |
4.19E-2 |
GO:0010941
|
regulation of cell death |
PTEN,NR4A2,TNF,PTENP1,CUL5,TLR2,ESR1,BCL2L11,IL6, |
4.28E-2 |
GO:0051092
|
positive regulation of NF-kappaB transcription factor activity |
TNF,TLR2,IL6, |
5.00E-2 |
GO:0032880
|
regulation of protein localization |
TNF,SMAD4,IL6,RAB14, |
5.35E-2 |
GO:0016477
|
cell migration |
PTEN,NR4A2,HIF1A,TNF,PTENP1,IL6, |
5.39E-2 |
GO:0010557
|
positive regulation of macromolecule biosynthetic process |
RNF4,NR4A2,HIF1A,TNF,ATXN1,SMAD4,IL6, |
6.10E-2 |
GO:0001775
|
cell activation |
TNF,TGFBR2,TLR2,IL6,IMPDH1, |
6.19E-2 |
GO:0046907
|
intracellular transport |
NPEPL1,VPS4B,ABCA1,KDELR2,TNF,ATXN1,RAB14, |
6.23E-2 |
GO:0048660
|
regulation of smooth muscle cell proliferation |
TNF,TGFBR2,IL6, |
6.26E-2 |
GO:0006468
|
protein amino acid phosphorylation |
ERBB4,CCND1,BMPR2,RPS6KA5,TNF,TGFBR2,GRK6, |
6.70E-2 |
GO:0009967
|
positive regulation of signal transduction |
HIF1A,TNF,SMAD4,ESR1,IL6, |
6.81E-2 |
GO:0032268
|
regulation of cellular protein metabolic process |
CCND1,BMPR2,TNF,SMAD4,SOCS1,IL6, |
7.04E-2 |
GO:0051098
|
regulation of binding |
TNF,SMAD4,TLR2,IL6, |
7.12E-2 |
GO:0010876
|
lipid localization |
VPS4B,ABCA1,TNF,PSAP, |
7.64E-2 |
GO:0051674
|
localization of cell |
PTEN,NR4A2,HIF1A,TNF,PTENP1,IL6, |
7.82E-2 |
GO:0048870
|
cell motility |
PTEN,NR4A2,HIF1A,TNF,PTENP1,IL6, |
7.82E-2 |
GO:0051241
|
negative regulation of multicellular organismal process |
BMPR2,TNF,TGFBR2,IL6, |
8.61E-2 |
GO:0006917
|
induction of apoptosis |
PTEN,TNF,PTENP1,CUL5,TLR2,BCL2L11, |
9.02E-2 |
GO:0012502
|
induction of programmed cell death |
PTEN,TNF,PTENP1,CUL5,TLR2,BCL2L11, |
9.12E-2 |
GO:0030334
|
regulation of cell migration |
ERBB4,PTEN,HIF1A,PTENP1,IL6, |
9.35E-2 |
GO:0016197
|
endosome transport |
VPS4B,ABCA1,RAB14, |
9.81E-2 |
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