Detail: | |
ncRNA Symmbol: | miR-207 |
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ncRNA Category: | miRNA |
Interaction Gene Symbol: | Akt3 |
Death Pathway: | apoptosis |
Expression Direction of ncRNA: | down |
Species: | Mus musculus |
Tissue: | cochlea hair cell |
PMID: | 25275594 |
Detail Description: | MicroRNA-207 enhances radiation-induced apoptosis by directly targeting Akt3 in cochlea hair cells.MicroRNA-207 enhances radiation-induced apoptosis by directly targeting Akt3 in cochlea hair cells. Furthermore, Akt3 was confirmed to be a direct target of miR-207. Downregulation of Akt3 mimics the effects of miR-207. MiR-207 enhances IR-induced apoptosis by directly targeting Akt3 and anti-miR-207 may have a potential role in protecting cochlea hair cells from IR. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.