The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-181
ncRNA Category:miRNA
Interaction Gene Symbol: Yy1
Death Pathway:apoptosis
Expression Direction of ncRNA:down
Species:Mus musculus
Tissue:cervical cancer cell
PMID: 25672374
Detail Description:

In addition, miR-181 also suppressed tumor growth in the nude mice. At the molecular level, it was found that Yin Yang 1, an oncogene in several types of human cancer, was negatively regulated by miR-181. Therefore, the findings of the present study suggest that exogenous overexpression of miR-181 may be a potential approach for the treatment of CC in the future. 

Select the ncRNA symbol and transcript of gene
Mature of miR-181    Transcript of Yy1    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.