The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-15b
ncRNA Category:miRNA
Interaction Gene Symbol: Bcl2l2
Death Pathway:autophagy
Expression Direction of ncRNA:
Species:Mus musculus
Tissue:neuroectodermal tissues
PMID: 21770019
Detail Description:

MicroRNAs miR-16-1 (miR-16) and miR-15b have been reported to function as tumor suppressors and negative regulators of cell growth. A number of studies support the existence of a complex interplay between autophagy, cell growth and apoptosis required for mammalian neural tube development. Bcl2 and the Bcl2-like anti-apoptotic proteins BCL2-associated athanogene 5 (Bag5) and BCL2-like 2 (Blc2l2) are targets of miR-16 and miR-15a (miRDB).  

Select the ncRNA symbol and transcript of gene
Mature of miR-15b    Transcript of Bcl2l2    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.