Detail: | |
ncRNA Symmbol: | miR-184 |
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ncRNA Category: | miRNA |
Interaction Gene Symbol: | MYC |
Death Pathway: | apoptosis |
Expression Direction of ncRNA: | up |
Species: | Homo sapiens |
Tissue: | Squamous Cell |
PMID: | 18451220 |
Detail Description: | Inhibition of miR-184 in tongue SCC cell lines could reduce cell proliferation rate. Down-regulation of c-Myc was observed in two cell lines in response to miR-184 inhibitor. Suppressing miR-184 could induce apoptosis in all three cell lines. Overexpression of miR-184 might play an oncogenic role in the antiapoptotic and proliferative processes of tongue SCC. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.