Psychiatric disorder (or Mental disorder) is a kind of behavioral or mental pattern that causing significant distress or impairment of personal functioning. Increasing evidence reveals that the development of psychiatric disorder results from a complex interplay between genetic and environmental factors. Here, to address the global view of psychiatric disorder’s genetic complexity, we developed PDR (Psychiatric Disorder Repository,, a resource for psychiatric disorder research with manual literature curation, comprising genomics, epigenomics, transcriptomics and proteomics for disease-associated variations. The current version of PDR documents more than 60,000 multi-omics relationships in psychiatric disorders, involving more than 33,000 genes, more than 100 psychiatric disorders determined from DSM-5 and 5 species. PDR will be of help in uncovering the generic organizing principles of psychiatric disorder.

How to cite:
Yan Huang, Xiaodan Li, Yuncong Zhang ... Dong Wang, PDR: a resource for psychiatric disorder research. 2018.

What's New?

  • PDR update
    June 2018
  • PDR construction
    November 2017
  • Data collection
    September 2017