Accumulated evidences suggest diverse non-coding RNAs (ncRNAs) involved in a wide variety of diseases progression. Hence, we have updated the MNDR v2.0 database by integrating experimental and prediction diverse ncRNA-disease associations from manual literatures curation and other resources under one common framework. The new developments in MNDR v2.0 include (1) over 220-fold ncRNA-disease associations enhancement than previous version (including lncRNA, miRNA, piRNA, snoRNA and more than 1,400 diseases); (2) integrating experimental and prediction evidence from 14 resources and prediction algorithms for each ncRNA-disease association; (3) mapping disease name to the Disease Ontology and Medical Subject Headings (MeSH); (4) providing a confidence score for each ncRNA-disease association; and (5) an increase of species coverage to 6 mammals.
How to cite :
MNDR v2.0: an updated resource of ncRNA-disease associations in mammals. Nucleic Acids Research. 2018. 46(D1):D371-D374. Link to pubmed
Mammalian ncRNA-disease repository: a global view of ncRNA-mediated disease network. Cell Death and Disease. 2013. 4:e765. Link to pubmed